@article{zheng_ballard_zheng_gao_ko_yang_brandt_lou_tai_lu_et al._2007, title={Design, synthesis, and evaluation of efflux substrate-metal chelator conjugates as potential antimicrobial agents}, volume={17}, ISSN={["1464-3405"]}, DOI={10.1016/j.bmcl.2006.10.094}, abstractNote={Maintaining a proper balance of metal concentrations is critical to the survival of bacteria. We have designed and synthesized a series of conjugates of metal chelators and efflux transporter substrates aimed at disrupting bacterial metal homeostasis to achieve bacterial killing. Biological studies showed that two of the compounds had very significant antimicrobial effect with an MIC value of 7.8 μg/mL against Gram-positive Bacillus subtilis.}, number={3}, journal={BIOORGANIC & MEDICINAL CHEMISTRY LETTERS}, author={Zheng, Yanling and Ballard, C. Eric and Zheng, Shi-Long and Gao, Xingming and Ko, Ko-Chun and Yang, Hsiuchin and Brandt, Gary and Lou, Xinhui and Tai, Phang C. and Lu, Chung-Dar and et al.}, year={2007}, month={Feb}, pages={707–711} }
 @article{yu_ballard_boyle_wang_2002, title={An inexpensive carbohydrate derivative used as a chiral auxiliary in the synthesis of alpha-hydroxy carboxylic acids}, volume={58}, ISSN={["0040-4020"]}, DOI={10.1016/S0040-4020(02)00871-2}, abstractNote={Protected α-hydroxy carboxylic acids were synthesized in moderate yield and high diastereoselectivity by alkylation of glycolate (α-hydroxy acetate) enolates using a d-fructose-derived chiral auxiliary. The new chiral center was assigned the R configuration based on comparisons of optical rotations and on one crystal structure analysis. This alkylation methodology is compatible with several hydroxyl protecting groups. The free hydroxy acids were obtained upon removal of the protecting group from the hydroxyl functionality followed by saponification.}, number={38}, journal={TETRAHEDRON}, author={Yu, HW and Ballard, CE and Boyle, PD and Wang, BH}, year={2002}, month={Sep}, pages={7663–7679} }
 @misc{ballard_yu_wang_2002, title={Recent developments in depsipeptide research}, volume={9}, ISSN={["1875-533X"]}, DOI={10.2174/0929867023371049}, abstractNote={This review focuses on the major developments in depsipeptide research since 1995. Depsipeptides are bio-oligomers composed of hydroxy and amino acids linked by amide and ester bonds. Many depsipeptides show very promising biological activities, including anticancer, antibacterial, antiviral, antifungal, anti-inflammatory, and anti-clotting or anti-antherogenic properties. In this report depsipeptides exhibiting these properties are discussed. Their isolation, structural determination, and notable structural features are discussed, but their biological properties and therapeutic potentials are emphasized. Depsipeptides have shown the greatest therapeutic potential as anticancer agents. Four depsipeptides have entered clinical trials for cancer treatment. Among the antiviral compounds discovered, the callipeltins and the quinoxapeptins are particularly promising due to their inhibitory activities against HIV. These compounds have the potential to be developed as anti-AIDS drugs or to serve as lead compounds for the discovery of structurally related anti-AIDS compounds. Antifungal compounds, such as the jaspamides, may lead to therapies against many of the opportunistic infections that accompany AIDS. Anti-inflammatory compounds such as SCH217048 act as neurokinin antagonists and may lead to anti-inflammatory treatments. Some depsipeptides such as micropeptins and A90720A have been found to be effective plasmin inhibitors, which have implications as treatments for cardiovascular diseases. Compounds such as SCH58149 help control the levels of HDL and LDL.}, number={4}, journal={CURRENT MEDICINAL CHEMISTRY}, author={Ballard, CE and Yu, H and Wang, B}, year={2002}, month={Feb}, pages={471–498} }
 @article{springsteen_ballard_gao_wang_wang_2001, title={The development of photometric sensors for boronic acids}, volume={29}, ISSN={["0045-2068"]}, DOI={10.1006/bioo.2001.1217}, abstractNote={Boronic acids bind certain 1,2- and 1,3-diols with high affinity through reversible formation of boronate esters. They have been utilized as the recognition moiety for artificial receptors, particularly receptors for carbohydrates that have cis-diol moieties. Therefore, sensors for boronic acids could serve as universal reporters for monitoring boronate formation. This paper reports the design and synthesis of a series of photometric chemosensors for phenylboronic acid using diethanolamine as the recognition moiety. Diethanolamine, which binds strongly to boronic acids, has been linked to three different types of optical reporters. A photoinduced electron transfer system based on the anthracene fluorophore has been used to create sensors that show up to a fivefold increase in fluorescent intensity in the presence of millimolar concentrations of phenylboronic acid. Sensor designs based on the restriction of free rotation of extended pi systems and on the perturbed electronic properties of azo dyes are also included. This work demonstrates that sensors based on several different designs can be used for the detection of boronic acids.}, number={5}, journal={BIOORGANIC CHEMISTRY}, author={Springsteen, G and Ballard, CE and Gao, S and Wang, W and Wang, BH}, year={2001}, month={Oct}, pages={259–270} }
 @article{shan_zheng_ballard_wang_borchardt_wang_2000, title={A facilitated cyclic ether formation and its potential application in solid-phase peptide and organic synthesis}, volume={48}, number={2}, journal={Chemical & Pharmaceutical Bulletin}, author={Shan, D. X. and Zheng, A. L. and Ballard, C. E. and Wang, W. and Borchardt, R. T. and Wang, B. H.}, year={2000}, pages={238–244} }
 @article{wang_jiang_ballard_wang_1999, title={Prodrug approaches to the improved delivery of peptide drugs}, volume={5}, number={4}, journal={Current Pharmaceutical Design}, author={Wang, W. and Jiang, J. and Ballard, C. E. and Wang, B.}, year={1999}, pages={265–287} }