Derek Adrian Brown

Works (3)

Updated: July 5th, 2023 15:59

2012 journal article

A resonance Raman enhancement mechanism for axial vibrational modes in the pyridine adduct of myoglobin proximal cavity mutant (H93G)

Journal of Physical Chemistry. B, Condensed Matter, Materials, Surfaces, Interfaces & Biophysical, 116(35), 10514–10521.

By: S. Franzen, D. Brown, J. Gaff & B. Delley

Source: NC State University Libraries
Added: August 6, 2018

2002 journal article

Formation of thiolate and phosphonate adlayers on indium-tin oxide: Optical and electronic characterization

Langmuir, 18(18), 6857–6865.

By: S. Brewer, D. Brown & S. Franzen 

Sources: NC State University Libraries, NC State University Libraries
Added: August 6, 2018

2002 journal article

Proximal ligand motions in H93G myoglobin

EUROPEAN JOURNAL OF BIOCHEMISTRY, 269(19), 4879–4886.

By: S. Franzen n , E. Peterson*, D. Brown n, J. Friedman*, M. Thomas * & S. Boxer *

author keywords: resonance Raman; heme; myoglobin; hemoglobin; ligand switch
MeSH headings : Animals; Heme / chemistry; Hydrogen Bonding; In Vitro Techniques; Ligands; Myoglobin / chemistry; Myoglobin / genetics; Photochemistry; Photolysis; Point Mutation; Protein Conformation; Recombinant Proteins / chemistry; Recombinant Proteins / genetics; Spectrum Analysis, Raman; Whales
TL;DR: The data presented here further substantiate the conclusion that a conformationally driven ligand switch exists in photolyzed H93G-*CO and suggest that ligand conformational changes in response to dynamic motions of the globin on the nanosecond and longer time scales are a general feature of the H 93G proximal cavity mutant. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

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