Works (9)

Updated: July 5th, 2023 16:02

2020 journal article

Mechanistic models of PLC/PKC signaling implicate phosphatidic acid as a key amplifier of chemotactic gradient sensing

PLOS COMPUTATIONAL BIOLOGY, 16(4).

By: J. Nosbisch n, A. Rahman n, K. Mohan n, T. Elston*, J. Bearโ€‰* & J. Haugh nโ€‰

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
MeSH headings : Animals; Chemotaxis / physiology; Diglycerides / metabolism; Fibroblasts / metabolism; Humans; Intracellular Signaling Peptides and Proteins / metabolism; Membrane Proteins / metabolism; Models, Theoretical; Myristoylated Alanine-Rich C Kinase Substrate / metabolism; Phosphatidic Acids / metabolism; Phosphatidic Acids / physiology; Phospholipase D / metabolism; Phosphorylation; Platelet-Derived Growth Factor / metabolism; Protein Kinase C / metabolism; Protein Kinase C / physiology; Signal Transduction / physiology; Type C Phospholipases / metabolism; Type C Phospholipases / physiology
Sources: Web Of Science, ORCID
Added: May 26, 2020

2004 journal article

Fluctuations in transcription factor binding can explain the graded and binary responses observed in inducible gene expression

JOURNAL OF THEORETICAL BIOLOGY, 226(1), 111โ€“121.

By: . Pirone n & T. Elston*

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: inducible gene expression; stochastic model; binary and graded response
MeSH headings : Animals; Cells / metabolism; DNA-Binding Proteins / metabolism; Gene Expression Regulation; Interleukin-2 / genetics; Models, Biological; NFATC Transcription Factors; Nuclear Proteins; Protein Binding; Signal Transduction / physiology; Transcription Factors / metabolism; Transcription, Genetic; beta-Galactosidase / genetics
Source: Web Of Science
Added: August 6, 2018

2002 journal article

The Brownian ratchet and power stroke models for posttranslational protein translocation into the endoplasmic reticulum

BIOPHYSICAL JOURNAL, 82(3), 1239โ€“1253.

By: T. Elston n

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
MeSH headings : Algorithms; Binding Sites; Biophysical Phenomena; Biophysics; Dose-Response Relationship, Drug; Endoplasmic Reticulum / metabolism; Least-Squares Analysis; Likelihood Functions; Models, Statistical; Models, Theoretical; Monte Carlo Method; Protein Binding; Protein Transport; Time Factors
Source: Web Of Science
Added: August 6, 2018

2001 journal article

A linear two-state model with complex dynamics

PHYSICS LETTERS A, 280(4), 204โ€“208.

By: T. Elston n & T. Kepler*

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
Source: Web Of Science
Added: August 6, 2018

2001 journal article

Stochasticity in transcriptional regulation: Origins, consequences, and mathematical representations

BIOPHYSICAL JOURNAL, 81(6), 3116โ€“3136.

By: T. Kepler n & T. Elston n

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
MeSH headings : Feedback, Physiological; Gene Expression Regulation; Models, Theoretical; Monte Carlo Method; Promoter Regions, Genetic; Stochastic Processes; Time Factors; Transcription, Genetic
Source: Web Of Science
Added: August 6, 2018

2000 journal article

A macroscopic description of biomolecular transport

JOURNAL OF MATHEMATICAL BIOLOGY, 41(3), 189โ€“206.

By: T. Elston n

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: diffusion coefficient; processive enzyme; stochastic process
MeSH headings : Algorithms; Biological Transport, Active; Diffusion; Kinetics; Models, Biological; Monte Carlo Method; Proteins / metabolism
Source: Web Of Science
Added: August 6, 2018

2000 journal article

Models of post-translational protein translocation

BIOPHYSICAL JOURNAL, 79(5), 2235โ€“2251.

By: T. Elston n

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
MeSH headings : Animals; Biological Transport, Active; Biophysical Phenomena; Biophysics; Endoplasmic Reticulum / metabolism; HSP70 Heat-Shock Proteins / chemistry; HSP70 Heat-Shock Proteins / metabolism; Kinetics; Mitochondria / metabolism; Models, Biological; Protein Conformation; Protein Processing, Post-Translational; Proteins / chemistry; Proteins / metabolism
Source: Web Of Science
Added: August 6, 2018

2000 journal article

Protein flexibility and the correlation ratchet

SIAM Journal on Applied Mathematics, 61(3), 842โ€“867.

By: T. Elston & C. Peskin

Source: NC State University Libraries
Added: August 6, 2018

2000 journal article

The role of protein flexibility in molecular motor function: Coupled diffusion in a tilted periodic potential

SIAM JOURNAL ON APPLIED MATHEMATICS, 60(3), 842โ€“867.

By: T. Elston* & C. Peskin

author keywords: biomolecular motors; Brownian ratchet; protein flexibility; stochastic processes; diffusion equation
Source: Web Of Science
Added: August 6, 2018

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