@article{anderson_hauser_martin_scott_ashley-koch_kim_monks_haynes_speer_pericak-vance_1999, title={Complete genomic screen for disease susceptibility loci innuclear families}, volume={17}, DOI={10.1002/gepi.1370170776}, abstractNote={AbstractWe performed genome‐wide model dependent and independent analyses on a simulated data set of 400 families segregating for a rare disorder. Regions on chromosomes 1, 3, and 5 were consistently indicated across the various analyses performed. Follow‐up analyses included stratification for locus heterogeneity and clinical phenotype and studies of gene×gene and gene×environment interaction. The region around D1G024 was most notable, showing strong association and linkage with the trait. We also identified regions D3G043–46 and D5G037–39 by strong linkage and association findings and region D1G001–09 by linkage analysis. A complex statistical interaction was suggested between D1G024, D3G046 and environmental factor 1. This report suggests that traditional methods of analysis can be implemented to analyze and describe the mechanisms that may underlie the more complex genetic disorders.}, number={Suppl.1}, journal={Genetic Epidemiology}, author={Anderson, J. L. and Hauser, E. R. and Martin, E. R. and Scott, W. K. and Ashley-Koch, A. and Kim, K. J. and Monks, S. A. and Haynes, C. S. and Speer, M. C. and Pericak-Vance, M. A.}, year={1999}, pages={S473–478} }
 @article{monks_martin_umbach_kaplan_1999, title={Two tests of association for a susceptibility locus for families of variable size: An example using two sampling strategies}, volume={17}, number={Suppl.1}, journal={Genetic Epidemiology}, author={Monks, S. A. and Martin, E. R. and Umbach, D. M. and Kaplan, N. L.}, year={1999}, pages={S655–660} }
 @article{monks_kaplan_weir_1998, title={A comparative study of sibship tests of linkage and/or association}, volume={63}, ISSN={["0002-9297"]}, DOI={10.1086/302104}, abstractNote={Population-based tests of association have used data from either case-control studies or studies based on trios (affected child and parents). Case-control studies are more prone to false-positive results caused by inappropriate controls, which can occur if, for example, there is population admixture or stratification. An advantage of family-based tests is that cases and controls are well matched, but parental data may not always be available, especially for late-onset diseases. Three recent family-based tests of association and linkage utilize unaffected siblings as surrogates for untyped parents. In this paper, we propose an extension of one of these tests. We describe and compare the four tests in the context of a complex disease for both biallelic and multiallelic markers, as well as for sibships of different sizes. We also examine the consequences of having some parental data in the sample.}, number={5}, journal={AMERICAN JOURNAL OF HUMAN GENETICS}, author={Monks, SA and Kaplan, NL and Weir, BS}, year={1998}, month={Nov}, pages={1507–1516} }