Yuan Liao

Works (7)

Updated: July 5th, 2023 16:02

2004 journal article

The effect of substitution patterns on the release rates of opioid peptides DADLE and [Leu(5)]-enkephalin from coumarin prodrug moieties

BIOORGANIC CHEMISTRY, 32(2), 109–123.

By: L. Zych n, W. Yang n, Y. Liao n, K. Griffin n & B. Wang n

author keywords: coumarin; cyclic prodrug; opioid peptide; esterase; structural effect
MeSH headings : Coumarins / chemistry; Coumarins / metabolism; Enkephalin, Leucine-2-Alanine / analogs & derivatives; Enkephalin, Leucine-2-Alanine / chemical synthesis; Enkephalin, Leucine-2-Alanine / chemistry; Enkephalin, Leucine-2-Alanine / metabolism; Enkephalins / chemical synthesis; Enkephalins / chemistry; Enkephalins / metabolism; Esterases / metabolism; Kinetics; Molecular Structure; Prodrugs / chemical synthesis; Prodrugs / chemistry; Prodrugs / metabolism
TL;DR: Aimed at further understanding the structure-release rate relationship of the coumarin-based cyclic prodrugs, a series of substituted coumarinic acid derivatives of opioid peptides, DADLE, and [Leu(5)]-enkephalin are synthesized and examined. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2003 journal article

A neural network model with bounded-weights for pattern classification

Computers & Operations Research, 31(9), 1411–1426.

By: Y. Liao n, S. Fang n  & H. L.W. Nuttle n

author keywords: pattern classification; neural networks; multi-layer perceptrons; radial basis function networks; support vector machines
TL;DR: A new neural network model is proposed based on the concepts of multi-layer perceptrons, radial basis functions, and support vector machines, which does not require that kernel functions satisfy Mercer's condition, and it can be readily extended to multi-class classification. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2003 journal article

Relaxed conditions for radial-basis function networks to be universal approximators

NEURAL NETWORKS, 16(7), 1019–1028.

By: Y. Liao n, S. Fang n  & H. Nuttle n

author keywords: universal approximation; radial-basis function networks
MeSH headings : Neural Networks, Computer
TL;DR: It is shown that RBFs are not required to be integrable for the REF networks to be universal approximators, and can uniformly approximate any continuous function on a compact set provided that the radial basis activation function is continuous almost everywhere, locally essentially bounded, and not a polynomial. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2000 journal article

The effect of phenyl substituents on the release rates of esterase-sensitive coumarin-based prodrugs

Chemical & Pharmaceutical Bulletin, 48(8), 1138–1147.

By: Y. Liao, S. Hendrata, S. Bae & B. Wang

Source: NC State University Libraries
Added: August 6, 2018

1999 journal article

Building fluorescent sensors by template polymerization: The preparation of a fluorescent sensor for L-tryptophan

BIOORGANIC CHEMISTRY, 27(6), 463–476.

By: Y. Liao n, W. Wang n & B. Wang n

TL;DR: A new way of making polymeric fluorescent sensors using template polymerization or molecular imprinting techniques is studied, which does not require the de novo design of the complementary binding site and does not rely on any specific structural features of the template molecule or prior knowledge of its three-dimensional structure. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

1999 journal article

Substituted coumarins as esterase-sensitive prodrug moieties with improved release rates

Bioorganic & Medicinal Chemistry Letters, 9(13), 1795–1800.

By: Y. Liao & B. Wang

Source: NC State University Libraries
Added: August 6, 2018

1998 journal article

Enantioselective polymeric transporters for tryptophan, phenylalanine, and histidine prepared using molecular imprinting techniques

BIOORGANIC CHEMISTRY, 26(6), 309–322.

By: Y. Liao n, W. Wang n & B. Wang n

TL;DR: Polymeric molecular transporters prepared using molecular imprinting techniques with D -tryptophan, D -phenylalanine, and D -histidine as the templates were found to be able to transport the template amino acids across a hydrophobic chloroform layer in a U-tube at rates that were 1.34- to 3.8-fold higher than the transport of their L -enantiomers. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
16. Peace, Justice and Strong Institutions (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

Citation Index includes data from a number of different sources. If you have questions about the sources of data in the Citation Index or need a set of data which is free to re-distribute, please contact us.

Certain data included herein are derived from the Web of Science© and InCites© (2025) of Clarivate Analytics. All rights reserved. You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.