Works (3)

Updated: July 5th, 2023 16:02

2002 journal article

Efficacy of monoclonal antibodies against defined antigens for passive immunotherapy of chronic gastrointestinal cryptosporidiosis


By: M. Riggs n, D. Schaefer n, S. Kapil n, L. Barley-Maloney n & L. Perryman n

MeSH headings : Animals; Antibodies, Monoclonal / therapeutic use; Bioreactors; Body Weight / drug effects; Chronic Disease; Cryptosporidiosis / drug therapy; Cryptosporidiosis / parasitology; Cryptosporidium parvum / drug effects; Disease Models, Animal; Feces / parasitology; Female; Gastrointestinal Diseases / drug therapy; Gastrointestinal Diseases / parasitology; Immunization, Passive; Mice; Mice, SCID; Oocytes; Treatment Outcome
TL;DR: The results indicate that anti-CSL MAb 3E2 has highly significant efficacy in reducing, but not eliminating, persistent C. parvum infection. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2001 journal article

Targeted disruption of CSL ligand-host cell receptor interaction in treatment of Cryptosporidium parvum infection

Journal of Eukaryotic Microbiology, (2001), 44S–46.

By: M. Riggs, D. Schaefer, S. Kapil, L. Barley-Maloney, L. Perryman & M. McNeil

Source: NC State University Libraries
Added: August 6, 2018

1999 journal article

Protection of calves against cryptosporidiosis with immune bovine colostrum induced by a Cryptosporidium parvum recombinant protein

VACCINE, 17(17), 2142–2149.

By: L. Perryman n, S. Kapil n, M. Jones n & E. Hunt n

author keywords: cryptosporidiosis; Cryptosporidium parvum; recombinant protein; colostrum; protection
MeSH headings : Animals; Antibodies, Protozoan / blood; Antigens, Protozoan / immunology; Cattle; Cattle Diseases / parasitology; Cattle Diseases / prevention & control; Colostrum / immunology; Cryptosporidiosis / parasitology; Cryptosporidiosis / prevention & control; Cryptosporidiosis / veterinary; Cryptosporidium parvum / genetics; Cryptosporidium parvum / immunology; Feces / parasitology; Female; Male; Pregnancy; Protozoan Vaccines / genetics; Protozoan Vaccines / immunology; Vaccines, Synthetic / immunology
TL;DR: The absence of diarrhea and 2.8%) reduction in oocyst excretion indicates that immune bovine colostrum induced by immunization with C. parvum recombinant protein rC7 provided substantial protection against cryptosporidiosis in neonatal calves. (via Semantic Scholar)
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Source: Web Of Science
Added: August 6, 2018

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