Sushila J. Kapil

Works (3)

Updated: July 5th, 2023 16:02

2002 journal article

Efficacy of monoclonal antibodies against defined antigens for passive immunotherapy of chronic gastrointestinal cryptosporidiosis

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 46(2), 275–282.

By: M. Riggs n, D. Schaefer n, S. Kapil n, L. Barley-Maloney n & L. Perryman n

MeSH headings : Animals; Antibodies, Monoclonal / therapeutic use; Bioreactors; Body Weight / drug effects; Chronic Disease; Cryptosporidiosis / drug therapy; Cryptosporidiosis / parasitology; Cryptosporidium parvum / drug effects; Disease Models, Animal; Feces / parasitology; Female; Gastrointestinal Diseases / drug therapy; Gastrointestinal Diseases / parasitology; Immunization, Passive; Mice; Mice, SCID; Oocytes; Treatment Outcome
TL;DR: The results indicate that anti-CSL MAb 3E2 has highly significant efficacy in reducing, but not eliminating, persistent C. parvum infection. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2001 journal article

Targeted disruption of CSL ligand-host cell receptor interaction in treatment of Cryptosporidium parvum infection

Journal of Eukaryotic Microbiology, (2001), 44S–46.

By: M. Riggs, D. Schaefer, S. Kapil, L. Barley-Maloney, L. Perryman & M. McNeil

Source: NC State University Libraries
Added: August 6, 2018

1999 journal article

Protection of calves against cryptosporidiosis with immune bovine colostrum induced by a Cryptosporidium parvum recombinant protein

VACCINE, 17(17), 2142–2149.

By: L. Perryman n, S. Kapil n, M. Jones n & E. Hunt n

author keywords: cryptosporidiosis; Cryptosporidium parvum; recombinant protein; colostrum; protection
MeSH headings : Animals; Antibodies, Protozoan / blood; Antigens, Protozoan / immunology; Cattle; Cattle Diseases / parasitology; Cattle Diseases / prevention & control; Colostrum / immunology; Cryptosporidiosis / parasitology; Cryptosporidiosis / prevention & control; Cryptosporidiosis / veterinary; Cryptosporidium parvum / genetics; Cryptosporidium parvum / immunology; Feces / parasitology; Female; Male; Pregnancy; Protozoan Vaccines / genetics; Protozoan Vaccines / immunology; Vaccines, Synthetic / immunology
TL;DR: The absence of diarrhea and 2.8%) reduction in oocyst excretion indicates that immune bovine colostrum induced by immunization with C. parvum recombinant protein rC7 provided substantial protection against cryptosporidiosis in neonatal calves. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

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