@article{shimizu_reininga_caicedo_mays_moore_olsen_ruzsa_coop_bustamante_purugganan_2008, title={Darwinian selection on a selfing locus (vol 306, pg 2081, 2004)}, volume={320}, number={5873}, journal={Science}, author={Shimizu, K. K. and Reininga, J. M. and Caicedo, A. L. and Mays, C. A. and Moore, R. C. and Olsen, K. M. and Ruzsa, S. and Coop, G. and Bustamante, C. D. and Purugganan, M. D.}, year={2008}, pages={176–176} }
 @article{shimizu_cork_caicedo_mays_moore_olsen_ruzsa_coop_bustamante_awadalla_et al._2004, title={Darwinian selection on a selfing locus (Retracted Article. See vol 320, pg 176, 2008)}, volume={306}, ISSN={["1095-9203"]}, DOI={10.1126/science.1103776}, abstractNote={
            The shift to self-pollination is one of the most prevalent evolutionary transitions in flowering plants. In the selfing plant
            Arabidopsis thaliana
            , pseudogenes at the
            SCR
            and
            SRK
            self-incompatibility loci are believed to underlie the evolution of self-fertilization. Positive directional selection has driven the evolutionary fixation of pseudogene alleles of
            SCR
            , leading to substantially reduced nucleotide variation. Coalescent simulations indicate that this adaptive event may have occurred very recently and is possibly associated with the post-Pleistocene expansion of
            A. thaliana
            from glacial refugia. This suggests that ancillary morphological innovations associated with self-pollination can evolve rapidly after the inactivation of the self-incompatibility response.
          }, number={5704}, journal={SCIENCE}, author={Shimizu, KK and Cork, JM and Caicedo, AL and Mays, CA and Moore, RC and Olsen, KM and Ruzsa, S and Coop, G and Bustamante, CD and Awadalla, P and et al.}, year={2004}, month={Dec}, pages={2081–2084} }
 @article{ruzsa_scandalios_2003, title={Altered Cu metabolism and differential transcription of Cu/ZnSod genes in a Cu/ZnSOD-deficient mutant of maize: Evidence for a Cu-responsive transcription factor}, volume={42}, ISSN={["0006-2960"]}, DOI={10.1021/bi020551x}, abstractNote={Maize inbred line A351 exhibits extremely low levels of Cu/Zn superoxide dismutase (SOD) isozymes, three cytosolic and one chloroplastic, which are increased by supplying copper to near-toxic concentrations. Activities of the copper enzymes cytochrome c oxidase and ascorbate oxidase are also reduced. The level of expression of the maize copper chaperone for SOD is normal to elevated. The gene transcript encoding chloroplastic SOD-1 is present at normal levels, whereas RNA levels of the cytosolic SODs are low and increase with added copper, suggesting a promoter element and copper-dependent transcription factor common to the three genes. Although a reduced level of high-affinity copper transport in A351 cannot be ruled out, high transcript levels of a constitutively expressed metallothionein, suggesting increased copper chelation capacity and creating a general copper-deprivation effect, seem to be a likely cause of the reduced levels of copper enzyme activity and Cu/ZnSod gene transcripts. While exogenous copper does not affect the wild-type SOD activity or protein, it increases wild-type Cu/ZnSod transcript levels in a response similar to that of several yeast genes involved in copper sequestration and antioxidant defense. A sequence that is highly homologous to those of the copper-responsive transcription factors ACE1 (Saccharomyces cerevisiae) and AMT1 (Candida glabrata) is present in the promoters of three maize Cu/ZnSod genes.}, number={6}, journal={BIOCHEMISTRY}, author={Ruzsa, SM and Scandalios, JG}, year={2003}, month={Feb}, pages={1508–1516} }
 @article{scandalios_acevedo_ruzsa_2000, title={Catalase gene expression in response to chronic high temperature stress in maize}, volume={156}, ISSN={["0168-9452"]}, DOI={10.1016/S0168-9452(00)00235-1}, abstractNote={Catalase gene expression was characterized in the scutellum of maize seedlings grown at normal (25 degrees C) and elevated temperatures (35 and 40 degrees C). Chronic elevated temperatures reduce scutellar catalase activity most noticeably in the inbred lines W64A and R6-67, which express all three CAT isozymes (CAT-1, CAT-2, and CAT-3). The observed decline in catalase activity is primarily attributed to a decrease in the amount of CAT-2 isozyme, due to diminished levels of the Cat2 transcript. As CAT-2 activity levels are regulated by the trans-acting gene locus Car1, it is possible that the Car1 gene product is inhibited at the elevated temperatures. In maize lines null for CAT-2 or both CAT-2 and CAT-3, the relative levels of Cat1 transcript, although steady throughout the 10 days post-imbibition scutellar profile, are slightly higher with increasing temperatures. This might indicate that, in thermally stressed seedlings, the accumulation and/or stability of Cat1 mRNA might compensate for the lack of Cat2 transcript in a tissue where Cat2 mRNA normally accumulates during the developmental period examined. These observations, along with the drastic reduction in seed germination and seedling height at chronically elevated growth temperatures, suggest that developmental arrest, rather than oxidative stress, might be the cause for the observed results relative to Cat gene expression under such conditions.}, number={1}, journal={PLANT SCIENCE}, author={Scandalios, JG and Acevedo, A and Ruzsa, S}, year={2000}, month={Jul}, pages={103–110} }
 @article{ruzsa_mylona_scandalios_1999, title={Differential response of antioxidant genes in maize leaves exposed to ozone}, volume={4}, ISSN={["1743-2928"]}, DOI={10.1179/135100099101534774}, abstractNote={Antioxidant enzymes function to eliminate reactive oxygen species (ROS) produced as a consequence of normal metabolic functions as well as environmental stress. In these studies, the responses of catalase (Cat), superoxide dismutase (Sod) and glutathione S-transferase (Gst), as well as D-ribulose-1,5-bisphosphate carboxylase/oxygenase (RbcS) genes were analyzed in 9- and 15-day postimbibition maize seedlings exposed to various ozone (O3) concentrations and time periods. After a single (acute) 6 h exposure, or 3, 6 and 10 consecutive days (chronic) exposure to O3, Cat1, Cat3, Gst1, Sod3, Sod4 and Sod4A transcript levels generally increased, while Cat2, RbcS and Sod1 levels decreased. Such changes in mRNA levels do not necessarily reflect parallel changes in the protein products of these genes. Changes in transcript levels seemed to be correlated with the spatial location of the isozymes encoded by the genes. The results are discussed with respect to gene regulation and expression, and the localization and function of these antioxidant enzymes during ozone-mediated oxidative stress.}, number={3}, journal={REDOX REPORT}, author={Ruzsa, SM and Mylona, P and Scandalios, JG}, year={1999}, pages={95–103} }