Works (2)

Updated: July 5th, 2023 15:59

2005 journal article

Diminished expression of C/EBP alpha in skin carcinomas is linked to oncogenic Ras and reexpression of C/EBP alpha in carcinoma cells inhibits proliferation

Cancer Research, 65(3), 861–867.

By: M. Shim, K. Powers, S. Ewing, S. Zhu & R. Smart

Source: NC State University Libraries
Added: August 6, 2018

2003 journal article

Lithium stabilizes the CCAAT/enhancer-binding protein alpha (C/EBP alpha) through a glycogen synthase kinase 3 (GSK3)-independent pathway involving direct inhibition of proteasomal activity


By: M. Shim n & R. Smart n

MeSH headings : Animals; CCAAT-Enhancer-Binding Protein-alpha / genetics; CCAAT-Enhancer-Binding Protein-alpha / metabolism; Cell Line; Cysteine Endopeptidases; Glycogen Synthase Kinases / genetics; Glycogen Synthase Kinases / metabolism; Lithium / pharmacology; Mice; Mice, Inbred BALB C; Multienzyme Complexes / antagonists & inhibitors; Mutagenesis, Site-Directed; Proteasome Endopeptidase Complex; Ubiquitin / metabolism
TL;DR: Results demonstrate C/EBPα is degraded via a ubiquitin-dependent proteasomal pathway, and LiCl stabilizes C/ EBPα through a GSK3-independent pathway involving direct inhibition of proteasome activity. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

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