Minsub Shim
Works (2)
Updated: July 5th, 2023 15:59
2005 journal article
Diminished expression of C/EBP alpha in skin carcinomas is linked to oncogenic Ras and reexpression of C/EBP alpha in carcinoma cells inhibits proliferation
Cancer Research, 65(3), 861–867.
Source: NC State University Libraries
Added: August 6, 2018
2003 journal article
Lithium stabilizes the CCAAT/enhancer-binding protein alpha (C/EBP alpha) through a glycogen synthase kinase 3 (GSK3)-independent pathway involving direct inhibition of proteasomal activity
JOURNAL OF BIOLOGICAL CHEMISTRY, 278(22), 19674–19681.
MeSH headings : Animals; CCAAT-Enhancer-Binding Protein-alpha / genetics; CCAAT-Enhancer-Binding Protein-alpha / metabolism; Cell Line; Cysteine Endopeptidases; Glycogen Synthase Kinases / genetics; Glycogen Synthase Kinases / metabolism; Lithium / pharmacology; Mice; Mice, Inbred BALB C; Multienzyme Complexes / antagonists & inhibitors; Mutagenesis, Site-Directed; Proteasome Endopeptidase Complex; Ubiquitin / metabolism
TL;DR:
Results demonstrate C/EBPα is degraded via a ubiquitin-dependent proteasomal pathway, and LiCl stabilizes C/ EBPα through a GSK3-independent pathway involving direct inhibition of proteasome activity.
(via Semantic Scholar)
open access via www.jbc.org (publisher PDF)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
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