Meredith Page Gooding
Works (5)
Updated: July 5th, 2023 16:02
2009 review
Environmental-endocrine control of reproductive maturation in gastropods: implications for the mechanism of tributyltin-induced imposex in prosobranchs
[Review of ]. ECOTOXICOLOGY, 19(1), 4–23.
author keywords: Mollusk; Endocrinology; Tributyltin; Imposex; Retinoid X-receptor
MeSH headings : Animal Nutritional Physiological Phenomena; Animals; Female; Male; Models, Biological; Photoperiod; Retinoid X Receptors / metabolism; Sex Characteristics; Sex Differentiation / drug effects; Signal Transduction / drug effects; Snails / drug effects; Snails / physiology; Temperature; Tretinoin / metabolism; Trialkyltin Compounds / metabolism; Trialkyltin Compounds / toxicity
TL;DR:
A cohesive model is provided for the environmental-endocrine regulation of reproduction in gastropods and it is proposed that TBT causes imposex through the inappropriate activation of this signaling pathway.
(via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2004 journal article
Seasonal variation in the regulation of testosterone levels in the eastern mud snail (Ilyanassa obsoleta)
Invertebrate Biology, 123(3), 237–243.
TL;DR:
This study provides compelling evidence that free testosterone levels in the mud snail are regulated through fatty acid esterification/de-esterification processes and this regulatory function contributes to seasonal fluctuations in freeosterone levels.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water
(OpenAlex)
Sources: NC State University Libraries, NC State University Libraries
Added: August 6, 2018
2002 journal article
The biocide tributyltin reduces the accumulation of testosterone as fatty acid esters in the mud snail (Ilyanassa obsoleta)
ENVIRONMENTAL HEALTH PERSPECTIVES, 111(4), 426–430.
author keywords: acyltransferase; fatty acid esters; Ilyanassa obsoleta; imposex; invertebrate endocrinology; mud snail; testosterone; tributyltin
MeSH headings : Animals; Disorders of Sex Development / chemically induced; Environmental Exposure; Esters; Fatty Acids / metabolism; Female; Male; Snails / physiology; Testosterone / blood; Testosterone / metabolism; Trialkyltin Compounds / adverse effects
TL;DR:
Results indicate that TBT elevates free testosterone levels in snails by decreasing the production or retention of testosterone-fatty acid esters, and may be a co-contributor to the testosterone fatty esterification process or a factor in the enhanced hydrolysis of the testosterone- fatty acid pool.
(via Semantic Scholar)
open access via europepmc.org (repository)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2001 journal article
Biotransformation and disposition of testosterone in the eastern mud snail Ilyanassa obsoleta
GENERAL AND COMPARATIVE ENDOCRINOLOGY, 122(2), 172–180.
author keywords: Ilyanassa obsoleta; mud snail; fatty acid conjugates; testosterone; imposex; invertebrate endocrinology; tributyltin
MeSH headings : Acyltransferases / metabolism; Animals; Biotransformation; Chromatography, Thin Layer; Disorders of Sex Development / metabolism; Fatty Acids, Nonesterified / blood; Hydrolysis; Snails / metabolism; Testosterone / pharmacokinetics
TL;DR:
Results indicate that AP1, which represents over 70% of the testosterone biotransformation products, is a fatty acid ester of testosterone, which might represent a target of TBT toxicity.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water
(OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
1999 journal article
Imposex in three marine gastropod species in Chile and potential impact on muriciculture
MARINE POLLUTION BULLETIN, 38(12), 1227–1231.
author keywords: imposex; gastropod; tributyltin; Chile; Chorus giganteus; Nucella
TL;DR:
Since sex of individuals in muriciculture is determined by the presence or absence of a penis, imposex may lead to erroneous classification of males and females and have a negative impact on sustainable cultivation and harvest of gastropods in Chile.
(via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
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