Ling-Jie Kong

Works (6)

Updated: July 5th, 2023 16:02

2004 journal article

A novel motif in geminivirus replication proteins interacts with the plant retinoblastoma-related protein

JOURNAL OF VIROLOGY, 78(9), 4817–4826.

By: G. Arguello-Astorga n, L. Lopez-Ochoa n, L. Kong n, B. Orozco n, S. Settlage n & L. Hanley-Bowdoin n 

MeSH headings : Amino Acid Motifs; Amino Acid Sequence; DNA-Binding Proteins / chemistry; DNA-Binding Proteins / genetics; DNA-Binding Proteins / metabolism; Geminiviridae / metabolism; Geminiviridae / pathogenicity; Solanum lycopersicum / virology; Molecular Sequence Data; Mutation; Plant Diseases / virology; Plant Leaves / virology; Plant Proteins / metabolism; Retinoblastoma Protein / metabolism; Tobacco / virology; Two-Hybrid System Techniques; Viral Proteins / chemistry; Viral Proteins / genetics; Viral Proteins / metabolism; Virus Replication
TL;DR: Results suggest that helix 4 and the conserved leucine residue are part of a pRBR-binding interface in begomovirus replication proteins. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
13. Climate Action (Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2004 patent

Geminivirus resistant transgenic plants

Washington, DC: U.S. Patent and Trademark Office.

By: L. Hanley-Bowdoin , B. Orozco, L. Kong & W. Gruissem

Source: NC State University Libraries
Added: August 6, 2018

2004 journal article

Interaction between a geminivirus replication protein and the plant sumoylation system

JOURNAL OF VIROLOGY, 78(6), 2758–2769.

By: A. Castillo *, L. Kong n, L. Hanley-Bowdoin n  & E. Bejarano *

MeSH headings : Amino Acid Sequence; Base Sequence; Geminiviridae / metabolism; Geminiviridae / pathogenicity; Geminiviridae / physiology; Molecular Sequence Data; Plants, Genetically Modified; Sequence Analysis, DNA; Tobacco / genetics; Tobacco / virology; Two-Hybrid System Techniques; Ubiquitin-Conjugating Enzymes / genetics; Ubiquitin-Conjugating Enzymes / metabolism; Viral Proteins / genetics; Viral Proteins / metabolism; Virus Replication
TL;DR: Effects on geminivirus replication were observed in transgenic plants with altered levels of SUMO, the substrate for UBC9, and the host cell sumoylation enzyme, NbSCE1 (N. benthamiana SUMO-conjugating enzyme, homolog to Saccharomyces cerevisiae U BC9), was found to interact specifically with RepAC1. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
13. Climate Action (Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2002 journal article

A geminivirus replication protein interacts with a protein kinase and a motor protein that display different expression patterns during plant development and infection

PLANT CELL, 14(8), 1817–1832.

By: L. Kong n & L. Hanley-Bowdoin n 

MeSH headings : Animals; Arabidopsis / genetics; Arabidopsis / growth & development; Arabidopsis / virology; Arabidopsis Proteins / genetics; Arabidopsis Proteins / isolation & purification; Arabidopsis Proteins / metabolism; Biological Transport / physiology; DNA, Viral / genetics; Geminiviridae / genetics; Geminiviridae / growth & development; Gene Expression Regulation, Developmental; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Plant; Histones / metabolism; In Situ Hybridization; Kinesins / genetics; Kinesins / metabolism; Microtubule Proteins / metabolism; Mitosis / genetics; Mitosis / physiology; Molecular Sequence Data; Phosphorylation; Protein Binding; Protein Interaction Mapping; Protein Kinases / genetics; Protein Kinases / isolation & purification; Protein Kinases / metabolism; Protein Serine-Threonine Kinases / metabolism; Tobacco / virology; Two-Hybrid System Techniques; Viral Proteins / genetics; Viral Proteins / metabolism
TL;DR: The results establish that AL1 interacts with host proteins involved in plant cell division and development, including a Ser/Thr kinase, a kinesin, and histone H3 as AL1 partners. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
13. Climate Action (Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2000 journal article

A geminivirus replication protein interacts with the retinoblastoma protein through a novel domain to determine symptoms and tissue specificity of infection in plants

EMBO JOURNAL, 19(13), 3485–3495.

By: L. Kong n, B. Orozco, J. Roe, S. Nagar, S. Ou, H. Feiler, T. Durfee, A. Miller ...

author keywords: AL1; cell cycle; differentiation; plant DNA virus; pRb
MeSH headings : Antigens, Polyomavirus Transforming / metabolism; Base Sequence; DNA Primers; Geminiviridae / isolation & purification; Geminiviridae / metabolism; Geminiviridae / physiology; Plants / virology; Protein Binding; Retinoblastoma Protein / metabolism; Viral Proteins / metabolism; Virus Replication
TL;DR: The pRBR binding domain of AL1 is mapped between amino acids 101 and 180 and two mutants are identified that are differentially impacted for AL1–pRBR interactions during geminivirus infection of plants. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
13. Climate Action (Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2000 journal article

The multifunctional character of a geminivirus replication protein is reflected by its complex oligomerization properties

JOURNAL OF BIOLOGICAL CHEMISTRY, 275(9), 6114–6122.

By: B. Orozco n, L. Kong n, L. Batts n, S. Elledge n & L. Hanley-Bowdoin n 

MeSH headings : Amino Acid Sequence; Animals; Conserved Sequence; DNA / metabolism; DNA-Binding Proteins / chemistry; Geminiviridae / chemistry; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Protein Conformation; Spodoptera / genetics; Transcription, Genetic; Transfection; Viral Proteins / chemistry; Viral Proteins / genetics; Virus Replication; Yeasts
TL;DR: Results suggested that different AL1 complexes mediate viral replication and transcriptional regulation and that replication interference involves multiple domains of the AL1 protein. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
13. Climate Action (Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

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