@article{moore_muñana_papich_nettifee osborne_2011, title={The pharmacokinetics of levetiracetam in healthy dogs concurrently receiving phenobarbital}, volume={34}, ISSN={0140-7783}, url={http://dx.doi.org/10.1111/j.1365-2885.2010.01188.x}, DOI={10.1111/j.1365-2885.2010.01188.x}, abstractNote={Moore, S.A., Muñana, K.R., Papich, M.G., Nettifee‐Osborne, J.A. The pharmacokinetics of levetiracetam in healthy dogs concurrently receiving phenobarbital.J. vet. Pharmacol. Therap.34, 31–34.}, number={1}, journal={Journal of Veterinary Pharmacology and Therapeutics}, publisher={Wiley}, author={Moore, S.A. and Muñana, K.R. and Papich, M.G. and Nettifee Osborne, J.A.}, year={2011}, month={Jan}, pages={31–34} } @article{azizoglu_osborne_wilson_kathariou_2009, title={Role of Growth Temperature in Freeze-Thaw Tolerance of Listeria spp.}, volume={75}, ISSN={["1098-5336"]}, DOI={10.1128/AEM.00458-09}, abstractNote={ABSTRACT}, number={16}, journal={APPLIED AND ENVIRONMENTAL MICROBIOLOGY}, author={Azizoglu, Reha O. and Osborne, J. and Wilson, S. and Kathariou, S.}, year={2009}, month={Aug}, pages={5315–5320} } @article{torbati_totapally_raszynski_osborne_zyl_kalomiris_wolfsdorf_2008, title={Age and Sex Differences in Brain Gene Expression in Neonatal Rats}, volume={39}, ISSN={0174-304X 1439-1899}, url={http://dx.doi.org/10.1055/s-0028-1105923}, DOI={10.1055/s-0028-1105923}, abstractNote={& Gene expression in the central nervous system is highly region-speci fi c. We tested the hypothesis that certain developmental biomarkers could be detected in the whole brain or in cortical, subcortical or cerebellar structures. Brain gene expressions of male and female rats at birth, 3 days, and 10 days of age were measured by micro-array technique ( (cid:1) 10 K genes; n = 9 / category). We found 53 signi fi cantly up-regulated and 8 down-regulated genes at 10 days}, number={04}, journal={Neuropediatrics}, publisher={Georg Thieme Verlag KG}, author={Torbati, D. and Totapally, B. and Raszynski, A. and Osborne, J. and Zyl, L. van and Kalomiris, S. and Wolfsdorf, J.}, year={2008}, month={Aug}, pages={219–225} } @article{adomas_heller_olson_osborne_karlsson_nahalkova_van zyl_sederoff_stenlid_finlay_et al._2008, title={Comparative analysis of transcript abundance in Pinus sylvestris after challenge with a saprotrophic, pathogenic or mutualistic fungus}, volume={28}, ISSN={["1758-4469"]}, DOI={10.1093/treephys/28.6.885}, abstractNote={To investigate functional differences in the recognition and response mechanisms of conifer roots to fungi with different trophic strategies, Pinus sylvestris L. was challenged with a saprotrophic fungus Trichoderma aureoviride Rifai. The results were compared with separate studies investigating pine interactions with a pathogen, Heterobasidion annosum (Fr.) Bref. sensu stricto and an ectomycorrhizal symbiont, Laccaria bicolor Maire (Orton). Global changes in the expression of 2109 conifer genes were assayed 1, 5 and 15 days after inoculation. Gene expression data from a cDNA microarray were analyzed by the 2-interconnected mixed linear model statistical approach. The total number of genes differentially expressed compared with the uninfected control was similar after challenge with the pathogen and the ectomycorrhizal symbiont, but the number of differentially expressed genes increased over time for H. annosum, and decreased for L. bicolor. Inoculation of pine roots with T. aureoviride resulted overall in a much lower number of genes with changed transcript levels compared with inoculation with H. annosum or L. bicolor. Functional classification of the differentially expressed genes revealed that the ectomycorrhizal fungus triggered transient induction of defence-related genes. The response and induction of defence against the pathogen was delayed and the magnitude increased over time. Thus, there were specific transcriptional responses depending on whether the conifer roots were challenged with mutualistic, saprotrophic or pathogenic fungi. This suggests that pine trees are able to recognize diverse fungal species and specifically distinguish whether they are pathogenic, neutral or beneficial microbial agents.}, number={6}, journal={TREE PHYSIOLOGY}, author={Adomas, Aleksandra and Heller, Gregory and Olson, Ake and Osborne, Jason and Karlsson, Magnus and Nahalkova, Jarmila and Van Zyl, Len and Sederoff, Ron and Stenlid, Jan and Finlay, Roger and et al.}, year={2008}, month={Jun}, pages={885–897} } @article{flammer_nettifee osborne_webb_foster_dillard_davis_2008, title={Pharmacokinetics of voriconazole after oral administration of single and multiple doses in African grey parrots (Psittacus erithacus timneh)}, volume={69}, ISSN={0002-9645}, url={http://dx.doi.org/10.2460/ajvr.69.1.114}, DOI={10.2460/ajvr.69.1.114}, abstractNote={Abstract}, number={1}, journal={American Journal of Veterinary Research}, publisher={American Veterinary Medical Association (AVMA)}, author={Flammer, Keven and Nettifee Osborne, Julie A. and Webb, Donna J. and Foster, Laura E. and Dillard, Stacy L. and Davis, Jennifer L.}, year={2008}, month={Jan}, pages={114–121} } @article{lund_osborne_2004, title={Validity and reliability of the neonatal skin condition score}, volume={33}, ISSN={["0884-2175"]}, DOI={10.1177/0884217504265174}, abstractNote={OBJECTIVE To demonstrate the validity and reliability of the Neonatal Skin Condition Scale (NSCS) used in the Association of Women's Health, Obstetric and Neonatal Nurses (AWHONN) and the National Association of Neonatal Nurses (NANN) neonatal skin care evidence-based practice project. SETTING NICU and well-baby units in 27 hospitals located throughout the United States. PARTICIPANTS Site coordinators (N = 27) and neonates (N = 1,006) observed during both the pre and postimplementation phases of the original neonatal skin care project. METHOD To assess reliability, two consecutive NSCS assessments on a single infant were analyzed. Site coordinators were contacted after the original project was concluded. Sites indicating that a single nurse scored all infant skin observations provided data that were used to evaluate intrarater reliability. Sites using more than one nurse to score skin observations provided data that were used to assess interrater reliability. To assess validity, the following variables were used from the original data set: the Neonatal Skin Condition Scale (NSCS), with three subscales for dryness, erythema, and breakdown; birth weight in grams; number of skin score observations for each infant; and the prevalence of infection, defined as a positive blood culture. RESULTS For intrarater reliability, 16 sites used a single nurse for all NSCS assessments; total NSCS assessments 475. For interrater reliability, 11 sites used multiple raters; total assessments 531. The NSCS demonstrated adequate reliability for each of the three subscales and for the total score, with the percent agreement between scores ranging from 68.7% to 85.4% (intrarater) and 65.9% to 89% (interrater); all Kappas were significant at p < .001 and were in the moderate range for reliability. The validity of the NSCS was demonstrated by the findings that smaller infants were 6 times more likely to have erythema (chi2(6) = 109.55, p < .0001), and approximately twice as likely to have the most severe breakdown (chi2(6) = 108.01, p < .0001). Infants with more observations (longer length of stay) had higher skin scores (odds ratio = 1.21, p < .0001), and an increased probability of infection was noted for infants with higher skin scores (odds ratio = 2.25, p < .0001). CONCLUSIONS The Neonatal Skin Condition Score (NSCS) is reliable when used by single and multiple raters to assess neonatal skin condition, even across weight groups and racial groups. Validity of the NSCS was demonstrated by confirmation of the relationship of the skin condition scores with birth weight, number of observations, and prevalence of infection.}, number={3}, journal={JOGNN-JOURNAL OF OBSTETRIC GYNECOLOGIC AND NEONATAL NURSING}, author={Lund, CH and Osborne, JW}, year={2004}, pages={320–327} } @article{osborne_2000, title={Seizing control of the situation: A guide to treating seizures in companion animals}, volume={21}, number={3}, journal={Veterinary Technician}, author={Osborne, J. N.}, year={2000}, pages={134} }