David V. Lieberman

Works (2)

Updated: July 5th, 2023 16:02

2004 article

Extraction of information on the buildup and consumption of reactive intermediates from quadruplex DNA assembly time courses

Lieberman, D. V., & Hardin, C. C. (2004, May 29). Biochimica Et Biophysica Acta (BBA) - Gene Structure and Expression.

By: D. Lieberman n & C. Hardin n

author keywords: intermediate species; quadruplex DNA assembly; time course
MeSH headings : Circular Dichroism; DNA / chemistry; Kinetics; Nucleic Acid Conformation
topics (OpenAlex): DNA and Nucleic Acid Chemistry; Advanced biosensing and bioanalysis techniques; RNA Interference and Gene Delivery
TL;DR: A method was developed to detect the time course of the overall presence of intermediate species during K+-induced DNA quadruplex assembly from single-stranded d(TG4) oligonucleotides in experiments in which only the combined circular dichroisms of all species present could be measured directly. (via Semantic Scholar)
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Added: August 6, 2018

1997 article

Allosteric Interactions between DNA Strands and Monovalent Cations in DNA Quadruplex Assembly:  Thermodynamic Evidence for Three Linked Association Pathways

Hardin, C. C., Corregan, M. J., Lieberman, D. V., & Brown, B. A. (1997, December 1). Biochemistry.

By: C. Hardin n, M. Corregan n, D. Lieberman n & B. Brown n

MeSH headings : Allosteric Regulation; Cations, Monovalent; Circular Dichroism; DNA / chemistry; Kinetics; Magnetic Resonance Spectroscopy; Nucleic Acid Conformation; Nucleic Acid Denaturation; Thermodynamics
topics (OpenAlex): DNA and Nucleic Acid Chemistry; Advanced biosensing and bioanalysis techniques; RNA Interference and Gene Delivery
TL;DR: It is proposed that, in addition to the more conventional assembly mechanisms involving duplex dimerization and stepwise strand addition, quadruplex formation can also proceed by triplex-triplex disproportionation. (via Semantic Scholar)
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Added: August 6, 2018

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