@article{palsson_gibson_2004, title={Association between nudeotide variation in Egfr and wing shape in Drosophild melanogaster}, volume={167}, ISSN={["1943-2631"]}, DOI={10.1534/genetics.103.021766}, abstractNote={Abstract}, number={3}, journal={GENETICS}, author={Palsson, A and Gibson, G}, year={2004}, month={Jul}, pages={1187–1198} }
 @article{palsson_rouse_riley-berger_dworkin_gibson_2004, title={Nucleotide variation in the Egfr locus of Drosophila melanogaster}, volume={167}, ISSN={["1943-2631"]}, DOI={10.1534/genetics.104.026252}, abstractNote={Abstract}, number={3}, journal={GENETICS}, author={Palsson, A and Rouse, A and Riley-Berger, R and Dworkin, I and Gibson, G}, year={2004}, month={Jul}, pages={1199–1212} }
 @article{dworkin_palsson_birdsall_gibson_2003, title={Evidence that Egfr contributes to cryptic genetic variation for photoreceptor determination in natural populations of Drosophila melanogaster}, volume={13}, ISSN={["1879-0445"]}, DOI={10.1016/j.cub.2003.10.001}, abstractNote={One objective of quantitative genetics is to identify the nucleotide variants within genes that contribute to phenotypic variation and susceptibility [1Stern D.L. Perspective evolutionary developmental biology and the problem of variation.Evolution. 2000; 54: 1079-1091PubMed Google Scholar]. In an evolutionary context, this means characterizing the molecular polymorphisms that modify the penetrance and expressivity of perturbed traits. A survey of association between 267 SNPs in almost 11 kb of the D. melanogaster Egfr and the degree of eye roughening due to a gain-of-function EgfrE1 allele crossed into 210 isogenic wild-type lines provides evidence that a handful of synonymous substitutions supply cryptic variation for photoreceptor determination. Ten sites exceed Bonferroni threshold for association in two sets of crosses to different EgfrE1 backgrounds including a particularly significant cluster of sites in tight linkage disequilibrium toward the 3′ end of the coding region. Epistatic interaction of this cluster with one other site enhances the expressivity of this haplotype. Replication of the strongest associations with an independent sample of 302 phenotypically extreme individuals derived from 1000 crosses of EgfrE1 to freshly trapped males was achieved using modified case-control and transmission-disequilibrium tests. A tendency for the rarer alleles to have more disrupted eye development suggests that mutation-selection balance is a possible mechanism contributing to maintaining cryptic variation for Egfr.}, number={21}, journal={CURRENT BIOLOGY}, author={Dworkin, I and Palsson, A and Birdsall, K and Gibson, G}, year={2003}, month={Oct}, pages={1888–1893} }
 @article{gibson_palsson_2001, title={Evolution: A complement for evolutionary genetics}, volume={11}, ISSN={["0960-9822"]}, DOI={10.1016/S0960-9822(01)00014-8}, abstractNote={Developmental geneticists' contribution to the study of the evolution of morphological divergence has proceeded along two lines: comparative analysis of gene expression and quantitative genetics. Recent studies highlight how complementation tests between species can bridge the gap between these approaches.}, number={2}, journal={CURRENT BIOLOGY}, author={Gibson, G and Palsson, A}, year={2001}, month={Jan}, pages={R74–R76} }
 @article{palsson_gibson_2000, title={Quantitative developmental genetic analysis reveals that the ancestral dipteran wing vein prepattern is conserved in Drosophila melanogaster}, volume={210}, ISSN={["0949-944X"]}, DOI={10.1007/s004270000107}, abstractNote={Quantitative complementation tests provide a quick test of the hypothesis that a particular gene contributes to segregating phenotypic variation. A set of wild-type alleles is assayed for variation in their ability to complement the degree of dominance of the quantitative effect of a loss of function allele. Analysis of 15 loci known to be involved in wing patterning in Drosophila melanogaster suggests that the genes decapentaplegic, thickveins, EGFR, argos and hedgehog, each of which are involved in secreted growth factor signaling, may contribute to wing shape variation. The phenotype of one deficiency, Df(2R)Px2, which removes blistered/Plexate, is also highly sensitive to the wild-type genetic background and at intermediate expressivity reveals six ectopic veins. These form in the same locations as a projection of the ancestral pattern of dipteran wing veins on- to the D. melanogaster wing. This atavistic phenotype indicates that the wing vein prepatterning mechanism can be conserved in highly derived species, and implies that homoplasic venation patterns may be produced by derepression of vein primordia.}, number={12}, journal={DEVELOPMENT GENES AND EVOLUTION}, author={Palsson, A and Gibson, G}, year={2000}, month={Dec}, pages={617–622} }
 @article{zimmerman_palsson_gibson_2000, title={Quantitative trait loci affecting components of wing shape in Drosophila melanogaster}, volume={155}, number={2}, journal={Genetics}, author={Zimmerman, E. and Palsson, A. and Gibson, G.}, year={2000}, pages={671–683} }