@article{hu_li_2003, title={On migration load of seeds and pollen grains in a local population}, volume={90}, ISSN={["1365-2540"]}, DOI={10.1038/sj.hdy.6800212}, abstractNote={We have extended Wright's model of migration load to hermaphrodite plants showing variation at a single locus with two alleles. The model incorporates independent migration of seeds and pollen grains, the selection at both the haploid gametophyte and the diploid sporophyte stages, and a mixed mating system. The analytical relations between migration load and migration rate of seeds and pollen grains are explicitly formulated. The results show that under certain conditions, seed flow can have a more effect on migration load than pollen flow. Pollen selection at the gametophyte stage cannot substantially affect the migration load at the sporophyte stage. Selection at the diploid sporophyte stage is critical in determining the migration load of pollen grains. The relative migration loads of pollen versus seeds can be approximately estimated in predominantly outcrossing populations by the ratio of pollen flow to twice the seed flow, when the selection coefficient (s(T)) is greater than, or approximately equal to, the migration rate (m).}, number={2}, journal={HEREDITY}, author={Hu, XS and Li, BL}, year={2003}, month={Feb}, pages={162–168} } @article{hu_li_2002, title={Linking evolutionary quantitative genetics to the conservation of genetic resources in natural forest populations}, volume={51}, number={5-6}, journal={Silvae Genetica}, author={Hu, X. S. and Li, B.}, year={2002}, pages={177–183} } @article{hu_li_2002, title={Seed and pollen flow and cline discordance among genes with different modes of inheritance}, volume={88}, DOI={10.1038/sj/hdy/6800030}, abstractNote={The relationships between seed and pollen flow and cline discordance/concordance between cytoplasmic and nuclear genes, with the incorporation of the effects of natural selection, are formulated for one locus with two alleles, under assumptions of random mating, no drift and no mutation. Results show that under certain conditions, the relative roles of seed and pollen flow in shaping cline discordance/ concordance are very similar to their roles in influencing population differentiation for selectively neutral markers with different modes of inheritance. Where the disequilibria between cytoplasmic and nuclear genes are of the order similar to selection coefficient, cline discordance/concordance can be predicted from the relative values of the ratio of pollen to seed flow and the ratio of selection coefficients. Where the disequilibria attained by seed and pollen flow are significant, the integrated cytonuclear data are recommended for cline analysis. In both cases, the relative rates of selection coefficients between cytoplasmic and nuclear genes can be roughly estimated according to their characteristic length.}, number={2002 Mar}, journal={Heredity}, author={Hu, X. S. and Li, B.}, year={2002}, pages={212–217} } @article{hu_li_2001, title={Assessment of the ratio of pollen to seed flow in a cline for genetic variation in a quantitative trait}, volume={87}, ISSN={["1365-2540"]}, DOI={10.1046/j.1365-2540.2001.00876.x}, abstractNote={A dispersal–selection cline model is analysed to evaluate the role of the ratio of pollen to seed flow (r) in spatial genetic variation, with a focus on clines in additive and dominant variances of major genes affecting a quantitative trait, assuming one locus with two alleles, no genetic drift and no mutation. It is shown that under weak selection, steady-state departures from the value at Hardy–Weinberg equilibrium (HWE) for genotype frequency (D) and additive variance (ΔVa) generally display a small value on one side of the selection boundary point, a high value around the point, and a moderate value on the other side of the boundary point. A large value of r can enhance formation of this pattern. However, this is not the case for clines in the average effect of a gene substitution (Δα) or in dominance variance (ΔVd), where large values of r can eradicate the clines. Direct use of their values at HWE to approximate the real case is acceptable. There is an expected turning point that divides clines of either additive variance or dominance variance into two subclines, each with a shorter width than that of allele frequency. Integration of these properties can help to indicate the existence of major genes affecting a quantitative trait.}, journal={HEREDITY}, author={Hu, XS and Li, B}, year={2001}, month={Oct}, pages={400–409} } @misc{wu_hu_han_2000, title={Molecular genetics and developmental physiology: Implications for designing better forest crops}, volume={19}, ISSN={["1549-7836"]}, DOI={10.1016/S0735-2689(00)80024-6}, abstractNote={ABSTRACT Current tree biology related to tree genetics and breeding has two important developments that have not well been integrated in the literature. The first is the physiological and biochemical dissection of plant yield, whereas the second is the genetic mapping based on molecular markers, such as RFLPs, RAPDs, AFLPs, and microsatellites. Genetic mapping has revolutionized traditional quantitative genetic analysis by which the genetic variation of a character is described in terms of its mean and (co)variance without the knowledge of the underlying genes. By integrating physiological and developmental studies of yield traits, genetic mapping can provide a unique means for detecting key QTL that play important roles in affecting tree growth and metabolism. The incorporation of these QTL into commercial populations through gene transformation or marker-assisted selection will move current breeding programs strictly based on an empirism to an approach that is mechanistically oriented. In this review, we discuss how plant physiology and development are merged with genetic mapping to formulate the strategy of molecular breeding in which superior forest crops are selected at the gene level. It is anticipated that this novel breeding strategy can potentially provide major breakthroughs for tree breeding.}, number={5}, journal={CRITICAL REVIEWS IN PLANT SCIENCES}, author={Wu, RL and Hu, XS and Han, YF}, year={2000}, pages={377–393} }