Guilin Qiao

Works (10)

Updated: February 10th, 2025 14:29

2001 article

Pharmacokinetics of sarafloxacin in pigs and broilers following intravenous, intramuscular, and oral single‐dose applications

Ding, H. Z., Zeng, Z. L., Fung, K. F., Chen, Z. L., & Qiao, G. L. (2001, October 11). Journal of Veterinary Pharmacology and Therapeutics.

By: H. Ding *, Z. Zeng *, K. Fung*, Z. Chen* & G. Qiao n

MeSH headings : Administration, Oral; Animals; Anti-Infective Agents / administration & dosage; Anti-Infective Agents / blood; Anti-Infective Agents / pharmacokinetics; Area Under Curve; Biological Availability; Chickens; Chromatography, High Pressure Liquid; Ciprofloxacin / administration & dosage; Ciprofloxacin / analogs & derivatives; Ciprofloxacin / blood; Ciprofloxacin / pharmacokinetics; Fluoroquinolones; Half-Life; Injections, Intramuscular; Injections, Intravenous; Male; Metabolic Clearance Rate; Species Specificity; Swine; Tissue Distribution
topics (OpenAlex): Antibiotics Pharmacokinetics and Efficacy; Antibiotic Resistance in Bacteria; Pneumonia and Respiratory Infections
TL;DR: Sarafloxacin was demonstrated to be more rapidly absorbed, more extensively distributed, and more quickly eliminated in broilers than in pigs and to maintain effective plasma concentrations with bacteria infections, in which MIC90 are <0.25 microg/mL. (via Semantic Scholar)
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Source: Web Of Science
Added: August 6, 2018

2000 article

Dermal Absorption and Tissue Disposition of 3,3′,14,4′-Tetrachloro biphenyl (TCB) in an Ex-vivo Pig Model: Assessing the Impact of Dermal Exposure Variables

Qiao, G., & Riviere, J. E. (2000, April 1). International Journal of Occupational and Environmental Health.

By: G. Qiao* & J. Riviere*

MeSH headings : Animals; Female; Linear Models; Pharmaceutical Vehicles; Pharmacokinetics; Polychlorinated Biphenyls / metabolism; Skin / drug effects; Skin Absorption; Soil Pollutants / metabolism; Swine
topics (OpenAlex): Animal testing and alternatives; Contact Dermatitis and Allergies; Pesticide Exposure and Toxicity
TL;DR: Dermal absorption data from liquid-organic or aqueousorganic mixtures may underestimate the risk of exposure to TCB-contaminated soil. (via Semantic Scholar)
Source: NC State University Libraries
Added: August 6, 2018

1997 journal article

Cutaneous toxicity of the benzidine dye direct red 28 applied as mechanistically-defined chemical mixtures (MDCM) in perfused porcine skin

Toxicology Letters, 93(2-3), 159–169.

By: R. Baynes n , N. Monteiro-Riviere n , G. Qiao n & J. Riviere n

Contributors: R. Baynes n , N. Monteiro-Riviere n , G. Qiao n & J. Riviere n

author keywords: chemical mixtures; cutaneous toxicity; benzidine dye
MeSH headings : Animals; Benzidines / pharmacokinetics; Benzidines / toxicity; Biomarkers; Coloring Agents / pharmacokinetics; Coloring Agents / toxicity; Dermotoxins / adverse effects; Dermotoxins / pharmacokinetics; Hazardous Waste / adverse effects; In Vitro Techniques; Perfusion; Skin Absorption; Solvents / pharmacokinetics; Solvents / toxicity; Surface-Active Agents / pharmacokinetics; Surface-Active Agents / toxicity; Swine; Toxicity Tests
topics (OpenAlex): Animal testing and alternatives; Skin Protection and Aging; Contact Dermatitis and Allergies
TL;DR: It is demonstrated that various mixtures, especially those containing SLS alter the epidermal barrier differently with complex interactions occurring simultaneously. (via Semantic Scholar)
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6. Clean Water and Sanitation (OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018

1997 article

Pentachlorophenol Dermal Absorption and Disposition from Soil in Swine: Effects of Occlusion and Skin Microorganism Inhibition

QIAO, G., BROOKS, J., & RIVIERE, J. (1997, December 1). Toxicology and Applied Pharmacology.

By: G. Qiao n, J. Brooks n & J. Riviere n

MeSH headings : Animals; Anti-Bacterial Agents / pharmacology; Carbon Radioisotopes; Female; Pentachlorophenol / metabolism; Pesticides / metabolism; Skin / drug effects; Skin / metabolism; Skin / microbiology; Skin Absorption; Soil; Soil Pollutants / metabolism; Swine
topics (OpenAlex): Effects and risks of endocrine disrupting chemicals; Toxic Organic Pollutants Impact; Animal testing and alternatives
TL;DR: Significant dermal absorption and extensive tissue persistence of PCP after soil exposure is demonstrated and exposure-specific PCP absorption and disposition profiles must be taken into consideration in risk analysis. (via Semantic Scholar)
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15. Life on Land (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

1997 article

Percutaneous Absorption of Volatile Chemicals

Riviere, J. E., Brooks, J. D., Qiao, G. L., & Monteiro-Riviere, N. A. (1997, November 1). (NTIS Report AFOSR G49620-95-1-0017), pp. 1–23.

By: J. Riviere*, J. Brooks*, G. Qiao* & N. Monteiro-Riviere* 

topics (OpenAlex): Polymer Science and PVC; Animal testing and alternatives
TL;DR: These studies demonstrated dose-dependent absorption of CPFB and DCB in skin which was further modulated by concomitant exposure to vehicle, and could be used as direct input into a systemic risk assessment model. (via Semantic Scholar)
Sources: NC State University Libraries, NC State University Libraries
Added: August 6, 2018

1996 article

The Use of Mechanistically Defined Chemical Mixtures (MDCM) to Assess Component Effects on the Percutaneous Absorption and Cutaneous Disposition of Topically Exposed Chemicals.

Qiao, G. L., Brooks, J. D., Baynes, R. E., Monteiro-Riviere, N. A., Williams, P. L., & Riviere, J. E. (1996, December 1). Toxicology and Applied Pharmacology, Vol. 141, pp. 473–486.

By: G. Qiao*, J. Brooks n, R. Baynes n, N. Monteiro-Riviere n , P. Williams  n & J. Riviere n

Contributors: G. Qiao*, J. Brooks n, R. Baynes n, N. MonteiroRiviere n , P. Williams  n & J. Riviere n

MeSH headings : Animals; Dimethyl Sulfoxide / pharmacology; Female; Insecticides / pharmacokinetics; Parathion / pharmacokinetics; Perfusion; Risk Assessment; Skin / blood supply; Skin / metabolism; Skin Absorption; Surface-Active Agents / pharmacology; Swine
topics (OpenAlex): Animal testing and alternatives; Contact Dermatitis and Allergies; Effects and risks of endocrine disrupting chemicals
TL;DR: This study indicated multiple levels of interactive effects on PA absorption which must be incorporated into any effort to identify critical mechanisms which affect risk assessment of topically exposed mixtures. (via Semantic Scholar)
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UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

1996 article

The Use of Mechanistically Defined Chemical Mixtures (MDCM) to Assess Mixture Component Effects on the Percutaneous Absorption and Cutaneous Disposition of Topically Exposed Chemicals

Williams, P. L., Thompson, D., Qiao, G. L., Monteiro-Riviere, N. A., Baynes, R. L., & Riviere, J. E. (1996, December 1). Toxicology and Applied Pharmacology, Vol. 141, pp. 487–496.

By: P. Williams  n, D. Thompson n, G. Qiao n, N. Monteiro-Riviere n , R. Baynes & J. Riviere n

Contributors: P. Williams  n, D. Thompson n, G. Qiao n, N. MonteiroRiviere n  & J. Riviere n

MeSH headings : Animals; Models, Biological; Perfusion; Risk Assessment; Skin / metabolism; Skin Absorption; Swine
topics (OpenAlex): Contact Dermatitis and Allergies; Advancements in Transdermal Drug Delivery; Pesticide Exposure and Toxicity
TL;DR: This model supports the MDCM concept that defining and then simulating those components of a complex mixture that could have a significant impact on the absorption of a marker toxic compound would be a useful screening approach in the risk assessment of topical chemical mixtures. (via Semantic Scholar)
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Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

1995 journal article

Significant Effects of Application Site and Occlusion on the Pharmacokinetics of Cutaneous Penetration and Biotransformation of Parathion in Vivo in Swine

Journal of Pharmaceutical Sciences, 84(4), 425–432.

By: G. Qiao n & J. Riviere n

MeSH headings : Adipose Tissue / metabolism; Administration, Topical; Animals; Biotransformation; Epidermis / metabolism; Female; Half-Life; Injections, Intravenous; Models, Biological; Parathion / administration & dosage; Parathion / pharmacokinetics; Skin Absorption / physiology; Swine
topics (OpenAlex): Pesticide Exposure and Toxicity; Advancements in Transdermal Drug Delivery; Insect and Pesticide Research
TL;DR: Systemic bioavailability of PA was higher from the back than from the abdomen, and Occlusion not only increased the amount of 14C absorption and shortened the mean residence time in most compartments but also altered the systemic versus cutaneous biotransformation pattern. (via Semantic Scholar)
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Sources: Web Of Science, Crossref
Added: August 6, 2018

1994 journal article

Percutaneous absorption, biotransformation and systemic disposition of parathion in vivo in swine. I. Comprehensive pharmacokinetic model

Drug Metabolism and Disposition, 22, 459–471.

By: G. Qiao, P. Williams & J. Riviere

Source: NC State University Libraries
Added: August 6, 2018

1993 journal article

Effects of Anatomical Site and Occlusion on the Percutaneous Absorption and Residue Pattern of 2,6-(ring-14C)Parathion in Vivo in Pigs

Toxicology and Applied Pharmacology, 122(1), 131–138.

By: G. Qiao n, S. Chang n & J. Riviere n

MeSH headings : Abdomen; Administration, Topical; Animals; Back; Buttocks; Drug Residues; Feces / chemistry; Female; Injections, Intravenous; Parathion / administration & dosage; Parathion / pharmacokinetics; Parathion / toxicity; Shoulder; Skin Absorption; Swine; Tissue Distribution
topics (OpenAlex): Pesticide Residue Analysis and Safety; Pesticide Exposure and Toxicity; Insect and Pesticide Research
TL;DR: The effects of anatomical site and occlusion on the percutaneous absorption and residue pattern of total 14C were investigated following topical application of 2,6-[ring-14C]parathion onto four skin sites in weanling swine using occluded and nonoccluded dosing systems, with shoulder and buttocks being similar, and the back the highest. (via Semantic Scholar)
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Sources: Web Of Science, Crossref
Added: August 6, 2018

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