Works (3)
Updated: July 5th, 2023 16:00
2004 journal article
Comparison of Li-Wong and loglinear mixed models for the statistical analysis of oligonucleotide arrays
BIOINFORMATICS, 20(4), 500–506.
MeSH headings : Algorithms; Computer Simulation; DNA / chemistry; DNA / genetics; Gene Expression Profiling / methods; Linear Models; Models, Genetic; Models, Statistical; Oligonucleotide Array Sequence Analysis / methods; Reproducibility of Results; Sensitivity and Specificity
TL;DR:
An empirical comparison of the two analysis-of-variance-style mixed models for probe-level, oligonucleotide array data based on a multiplicative parametrization is provided, and finds the models perform quite similarly across most genes, but with some interesting and important distinctions.
(via Semantic Scholar)
open access via academic.oup.com (publisher PDF)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2004 journal article
Variation an transcript abundance during somatic embryogenesis in gymnosperms
TREE PHYSIOLOGY, 24(10), 1073–1085.
author keywords: embryo development; gene expression; hybridization; microarray; Picea abies; Pinus taeda
MeSH headings : Cycadopsida / genetics; Cycadopsida / physiology; Gene Expression Regulation, Plant / physiology; Genetic Variation / physiology; Oligonucleotide Array Sequence Analysis; Picea / genetics; Picea / physiology; Seeds / genetics; Seeds / physiology; Transcription, Genetic / physiology; Trees / genetics; Trees / physiology
TL;DR:
Comparison of transcript levels between successive stages of embryogenesis allowed us to identify several genes that showed unique expression responses during normal development, including proteins involved in detoxification processes, methionine synthesis and utilization, and carbohydrate metabolism.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2002 journal article
A systematic statistical linear modeling approach to oligonucleotide array experiments
MATHEMATICAL BIOSCIENCES, 176(1), 35–51.
author keywords: microarray; mixed model; split plot; probe
MeSH headings : Cells, Cultured; Humans; Models, Statistical; Oligonucleotide Array Sequence Analysis / methods; Radiation, Ionizing; Transcription, Genetic
TL;DR:
The approach employs classical linear mixed models and operates on a gene-by-gene basis and simultaneously considers the data across all chips in an experiment, which can accommodate complex experiments involving many kinds of treatments and test for their effects at the probe level.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018