@article{mccall_grillo_comins_2008, title={N-Acyldihydropyridones as Synthetic Intermediates. A Stereoselective Synthesis of Acyclic Amino Alcohols Containing Multiple Chiral Centers}, volume={73}, ISSN={["0022-3263"]}, DOI={10.1021/jo802029y}, abstractNote={Various multisubstituted piperidines containing a phenyl group at C-2 can be opened regio- and stereoselectively with cyanogen bromide. The ring-opened products contain useful cyanamide and benzylic bromide functional groups. The benzyl bromide can be cleanly reduced, or substituted with various nucleophiles via an S(N)2 process to add additional heteroatoms stereoselectively. This methodology is useful for the stereoselective synthesis of uniquely substituted alkylamine derivatives containing multiple chiral centers and various functionality. Diastereomerically pure amino alcohols containing three to five contiguous stereocenters were prepared using this strategy.}, number={24}, journal={JOURNAL OF ORGANIC CHEMISTRY}, author={McCall, W. Stephen and Grillo, Teresa Abad and Comins, Daniel L.}, year={2008}, month={Dec}, pages={9744–9751} } @article{mccall_grillo_comins_2008, title={Stereoselective synthesis of acyclic amino alcohols via von Braun ring opening of chiral piperidines}, volume={10}, ISSN={["1523-7052"]}, DOI={10.1021/ol801123x}, abstractNote={Multisubstituted piperidines containing a phenyl group at C-2 can be opened regio- and stereoselectively with cyanogen bromide. The ring-opened products contain useful cyanamide and benzylic bromide functional groups. This methodology is useful for the stereoselective synthesis of uniquely substituted alkylamine derivatives containing multiple chiral centers and various functionality.}, number={15}, journal={ORGANIC LETTERS}, author={McCall, W. Stephen and Grillo, Teresa Abad and Comins, Daniel L.}, year={2008}, month={Aug}, pages={3255–3257} } @article{williams_grillo_comins_2002, title={A novel free-radical ring contraction of a cyclic carbamate}, volume={67}, ISSN={["0022-3263"]}, DOI={10.1021/jo0163290}, abstractNote={During a study on iodocyclocarbamation reactions of 2-styryl-4-piperidones, a novel ring contraction was observed. Iodocyclocarbamation of 2-styryl-4-piperidone 3 gave the bicyclic carbamate 4. Reduction of 4 under free-radical conditions effected a stereoselective ring contraction to provide oxazolidinone 6. A three-electron-three-center mechanism is proposed.}, number={6}, journal={JOURNAL OF ORGANIC CHEMISTRY}, author={Williams, AL and Grillo, TA and Comins, DL}, year={2002}, month={Mar}, pages={1972–1973} } @article{comins_sandelier_grillo_2001, title={Asymmetric synthesis of (+)-deoxoprosopinine}, volume={66}, DOI={10.1021/jo015834u}, abstractNote={ADVERTISEMENT RETURN TO ISSUEPREVNoteNEXTAsymmetric Synthesis of (+)-DeoxoprosopinineDaniel L. Comins, Matthew J. Sandelier, and Teresa Abad GrilloView Author Information Department of Chemistry, North Carolina State University, Raleigh, North Carolina 27695-8204 [email protected]Cite this: J. Org. Chem. 2001, 66, 20, 6829–6832Publication Date (Web):September 6, 2001Publication History Received13 June 2001Published online6 September 2001Published inissue 1 October 2001https://doi.org/10.1021/jo015834uCopyright © 2001 American Chemical SocietyRequest reuse permissionsArticle Views843Altmetric-Citations44LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit Read OnlinePDF (53 KB) Get e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information SUBJECTS:Cyclization,Enantioselective synthesis,Materials,Organic compounds,Pharmaceuticals Get e-Alerts}, number={20}, journal={Journal of Organic Chemistry}, author={Comins, D. L. and Sandelier, M. J. and Grillo, T. A.}, year={2001}, pages={6829–6832} }