Darell W. McCoy

Works (6)

Updated: July 5th, 2023 16:00

2003 article

A chicken mRNA similar to heterogeneous nuclear ribonucleoprotein H1

Mozdziak, P. E., Giamario, C., Dibner, J. J., & McCoy, D. W. (2003, December 24). Comparative Biochemistry and Physiology Part B Biochemistry and Molecular Biology, Vol. 137, pp. 89–94.

By: P. Mozdziak n , C. Giamario n, J. Dibner & D. McCoy n

Contributors: P. Mozdziak n , C. Giamario n, J. Dibner & D. McCoy n

author keywords: avian; RNA binding proteins; poultry; sequencing; RACE; chicken; amino acid; hnRNP
MeSH headings : Amino Acid Sequence; Animals; Base Sequence; Blotting, Northern; Chickens; Cloning, Molecular; DNA, Complementary; Gene Expression; Heterogeneous-Nuclear Ribonucleoproteins / genetics; Molecular Sequence Data; RNA, Messenger / genetics; Sequence Alignment
topics (OpenAlex): RNA Research and Splicing; RNA and protein synthesis mechanisms; RNA modifications and cancer
TL;DR: The objective of these experiments was to clone a cDNA for a chicken protein similar to other previously reported heterogeneous ribonucleoproteins for other species, and the deduced amino acid sequence was approximately 86% identical to corresponding regions of human, mouse, or zebrafish proteins similar to heterogeneous nuclear ribon nucleoprotein H1. (via Semantic Scholar)
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Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2003 article

Development of transgenic chickens expressing bacterial β‐galactosidase

Mozdziak, P. E., Borwornpinyo, S., McCoy, D. W., & Petitte, J. N. (2003, February 6). Developmental Dynamics, Vol. 226, pp. 439–445.

By: P. Mozdziak n , S. Borwornpinyo n, D. McCoy n & J. Petitte n 

Contributors: P. Mozdziak n , S. Borwornpinyo n, D. McCoy n & J. Petitte n 

author keywords: lacZ; myoblast; muscle; embryo; E. coli
MeSH headings : Animals; Animals, Genetically Modified; Chick Embryo; Chickens; Female; Gene Expression; Gene Transfer Techniques; Lac Operon; Male; Retroviridae / genetics; beta-Galactosidase / genetics
topics (OpenAlex): Animal Genetics and Reproduction; CRISPR and Genetic Engineering; Virus-based gene therapy research
TL;DR: The replication‐defective retroviral SNTZ vector carrying the lacZ gene with a nuclear localized signal was injected into the subgerminal cavity of freshly laid eggs, and the chickens were screened for the LacZ gene by using the polymerase chain reaction. (via Semantic Scholar)
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Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2003 article

Glyceraldehyde-3-Phosphate Dehydrogenase Expression Varies With Age and Nutrition Status

Mozdziak, P. E., Dibner, J. J., & McCoy, D. W. (2003, April 25). Nutrition, Vol. 19, pp. 438–440.

By: P. Mozdziak n , J. Dibner & D. McCoy n

Contributors: P. Mozdziak n , J. Dibner & D. McCoy n

author keywords: skeletal muscle; northern analysis; nutrition; starvation; avian
MeSH headings : Age Factors; Animal Nutritional Physiological Phenomena; Animals; Animals, Newborn; Blotting, Northern; Chickens / growth & development; Chickens / metabolism; Food Deprivation; Gene Expression Regulation, Enzymologic; Glyceraldehyde-3-Phosphate Dehydrogenases / genetics; Glyceraldehyde-3-Phosphate Dehydrogenases / metabolism; Male; Nutritional Status; Pectoralis Muscles / enzymology; RNA / analysis; Random Allocation
topics (OpenAlex): Molecular Biology Techniques and Applications; Muscle Physiology and Disorders; Virus-based gene therapy research
TL;DR: GAPDH expression changes with age and nutrition status in the early posthatch chick, suggesting that GAPDH is not a proper internal standard for muscle studies using quantitative northern analysis. (via Semantic Scholar)
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2. Zero Hunger (OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2002 article

Early Posthatch Starvation Induces Myonuclear Apoptosis in Chickens

Mozdziak, P. E., Evans, J. J., & McCoy, D. W. (2002, May 1). Journal of Nutrition.

By: P. Mozdziak n , J. Evans n & D. McCoy n

author keywords: apoptosis; skeletal muscle; myonucleus; chickens; starvation
MeSH headings : Animals; Apoptosis / physiology; Chickens; Food Deprivation; Histocytochemistry; Male; Muscle Development; Muscle Fibers, Skeletal / pathology; Muscle Fibers, Skeletal / physiology; Muscle, Skeletal / growth & development; Muscle, Skeletal / pathology; Pectoralis Muscles / growth & development; Pectoralis Muscles / pathology; Starvation / pathology; Starvation / physiopathology
topics (OpenAlex): Muscle Physiology and Disorders; Animal Nutrition and Physiology; Calpain Protease Function and Regulation
TL;DR: It appears that apoptosis is a mechanism contributing to the smaller myofiber size observed when feed is not provided early posthatch, and this mechanism is likely to be responsible for reducing the total number of apoptotic nuclei in cells. (via Semantic Scholar)
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Source: Web Of Science
Added: August 6, 2018

2002 article

The effect of early posthatch nutrition on satellite cell mitotic activity

Mozdziak, P. E., Walsh, T. J., & McCoy, D. W. (2002, November 1). Poultry Science, Vol. 81, pp. 1703–1708.

By: P. Mozdziak n , T. Walsh n & D. McCoy n

Contributors: P. Mozdziak n , T. Walsh n & D. McCoy n

author keywords: turkey; oasis hatchling supplement; growth; skeletal muscle; myofiber
MeSH headings : Age Factors; Animal Nutritional Physiological Phenomena; Animals; Antimetabolites; Bromodeoxyuridine; Image Processing, Computer-Assisted; Immunohistochemistry / veterinary; Mitosis / physiology; Pectoralis Muscles / cytology; Pectoralis Muscles / growth & development; Pectoralis Muscles / metabolism; Random Allocation; Satellite Cells, Skeletal Muscle / cytology; Turkeys / growth & development
topics (OpenAlex): Animal Nutrition and Physiology; Animal Genetics and Reproduction; Aquaculture Nutrition and Growth
TL;DR: The results of the current study suggest that any improvements in meat yield through early nutritional supplementation do not appear to occur through a satellite cell pathway and that there is no compensatory response in the satellite cell population following refeeding after early posthatch starvation. (via Semantic Scholar)
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2. Zero Hunger (OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2002 article

The effect of early posthatch starvation on calpain mRNA levels

Mozdziak, P. E., Dibner, J. J., & McCoy, D. W. (2002, October 1). Comparative Biochemistry and Physiology Part B Biochemistry and Molecular Biology, Vol. 133, pp. 221–226.

By: P. Mozdziak n , J. Dibner & D. McCoy n

Contributors: P. Mozdziak n , J. Dibner & D. McCoy n

author keywords: chicken; muscle; myofiber; protease; yolk; myofibril; avian; Pectoralis thoracicus
MeSH headings : Age Factors; Animals; Animals, Newborn; Blotting, Northern; Calpain / genetics; Chickens; Down-Regulation; Food Deprivation; Male; Muscle, Skeletal / chemistry; Muscle, Skeletal / metabolism; RNA, Messenger / analysis; Starvation / genetics
topics (OpenAlex): Animal Nutrition and Physiology; Meat and Animal Product Quality; Calpain Protease Function and Regulation
TL;DR: In the early posthatch chicken, it appears that the calpain system may not be affected by the presence of oral nutrition, and that there is an age-related downregulation of p94 calpain mRNA expression. (via Semantic Scholar)
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UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

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