Detection of DNA Hybridization on Gold Surfaces by Polarization Modulation Infrared Reflection Absorption Spectroscopy
Brewer, S. H., Anthireya, S. J., Lappi, S. E., Drapcho, D. L., & Franzen, S. (2002, May 1). Langmuir, Vol. 18, pp. 4460–4464.
topics (OpenAlex): Advanced biosensing and bioanalysis techniques; Gold and Silver Nanoparticles Synthesis and Applications; DNA and Nucleic Acid Chemistry
TL;DR:
Polarization modulation infrared reflection absorption spectroscopy (PM-IRRAS) was used to detect DNA hybridization on gold surfaces and contained absorptive features indicative of DNA arising from the phosphodiester backbone and the purine and pyrimidine rings.
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