Works (2)
Updated: July 5th, 2023 16:00
2002 journal article
Identification and quantification of protecting groups remaining in commercial oligonucleotide products using monoclonal antibodies
ANALYTICAL BIOCHEMISTRY, 306(1), 135–143.
author keywords: DNA; RNA; automated synthesis; protecting group detection; quality control
MeSH headings : Antibodies, Monoclonal / immunology; Antibody Specificity; Chromatography, High Pressure Liquid; DNA / chemistry; DNA / immunology; Enzyme-Linked Immunosorbent Assay; Immunoblotting / methods; Molecular Structure; Oligonucleotides / chemistry; Oligonucleotides / immunology; Quality Control; RNA / chemistry; RNA / immunology; Sensitivity and Specificity; Spectrum Analysis
TL;DR:
Monoclonal antibodies selectively identify and quantify picomoles of remaining protecting groups on antisense therapeutics and oligonucleotide diagnostics.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2002 personal communication
QC in antisense oligo synthesis
Source: NC State University Libraries
Added: August 6, 2018
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