Weijuan Ni

Works (5)

Updated: July 5th, 2023 15:59

2004 journal article

Regulating the fluorescence intensity of an anthracene boronic acid system: a B-N bond or a hydrolysis mechanism?

BIOORGANIC CHEMISTRY, 32(6), 571–581.

By: W. Ni n, G. Kaur *, G. Springsteen n, B. Wang * & S. Franzen n 

author keywords: anthracene-based fluorescent boronic acid; B-N bond; PET
MeSH headings : Anthracenes / chemistry; Boron / chemistry; Boron Compounds / chemistry; Boronic Acids / chemistry; Carbohydrates / chemistry; Fluorescence; Hydrogen-Ion Concentration; Hydrolysis; Nitrogen / chemistry
TL;DR: This work suggests a possible alternative mechanism for the fluorescence change upon the formation of a boronic acid (1a) complex with diols, which results in the protonation of the amine nitrogen if the reactions are carried out in a protic solvent such as water. (via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (OpenAlex)
Sources: Web Of Science, ORCID
Added: August 6, 2018

2004 journal article

The design of boronic acid spectroscopic reporter compounds by taking advantage of the pK(a)-lowering effect of diol binding: Nitrophenol-based color reporters for diols

JOURNAL OF ORGANIC CHEMISTRY, 69(6), 1999–2007.

By: W. Ni n, H. Fang  n, G. Springsteen n & B. Wang  n

MeSH headings : Boronic Acids / chemical synthesis; Carbohydrates / analysis; Colorimetry; Cyclopentanes / chemistry; Drug Design; Fructose / chemistry; Glucose / chemistry; Glycols / analysis; Hydrogen-Ion Concentration; Molecular Structure; Nitrophenols / chemistry; Polymers / chemistry; Spectrophotometry, Ultraviolet / methods
TL;DR: Two nitrophenol-based boronic acid reporter compounds are designed and synthesized that change ionization states and therefore spectroscopic properties upon diol binding and show significant UV changes upon addition of saccharides. (via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2003 journal article

Study of the mechanism of electron-transfer quenching by boron-nitrogen adducts in fluorescent sensors

JOURNAL OF PHYSICAL CHEMISTRY B, 107(47), 12942–12948.

By: S. Franzen n , W. Ni n & B. Wang n

UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID
Added: August 6, 2018

2002 journal article

A glucose-selective fluorescence sensor based on boronic acid-diol recognition

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 12(23), 3373–3377.

By: . Karnati n, X. Gao n, S. Gao n, W. Yang n, W. Ni n, S. Sankar n, B. Wang n

MeSH headings : Biosensing Techniques / methods; Boron Compounds / chemical synthesis; Boron Compounds / chemistry; Fluorescence; Fluorescent Dyes / chemical synthesis; Fluorescent Dyes / chemistry; Glucose / analogs & derivatives; Glucose / analysis; Magnetic Resonance Spectroscopy; Sensitivity and Specificity; Spectrometry, Fluorescence
TL;DR: A glucose selective diphenylboronic acid fluorescent sensor (10a) with a K(a) of 1472M(-1) has been synthesized and evaluated and 1H NMR studies indicate that sensor 10a binds with alpha-D-glucofuranose in a bidentate manner (1:1 ratio). (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2002 journal article

Diboronic acids as fluorescent probes for cells expressing sialyl Lewis X

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 12(16), 2175–2177.

By: W. Yang n, S. Gao n, X. Gao n, V. Karnati n, W. Ni n, B. Wang n, W. Hooks*, J. Carson*, B. Weston*

MeSH headings : Animals; Binding Sites; Boronic Acids / chemical synthesis; Boronic Acids / chemistry; Boronic Acids / metabolism; COS Cells; Fluorescence; Gene Expression; Humans; Mice; Molecular Structure; Oligosaccharides / analysis; Oligosaccharides / chemistry; Oligosaccharides / genetics; Sialyl Lewis X Antigen; Staining and Labeling / methods; Tumor Cells, Cultured
TL;DR: A series of fluorescent diboronic acids was synthesized in nine steps as potential sensors for sialyl Lewis X (sLex) and compound 7e was found to show the strongest fluorescence enhancement upon binding with sLex. (via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

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