Wenqian Yang

Works (11)

Updated: July 5th, 2023 15:59

2005 article

A new type of boronic acid fluorescent reporter compound for sugar recognition

Yang, W., Lin, L., & Wang, B. (2005, October 3). Tetrahedron Letters.

By: W. Yang n, L. Lin  n & B. Wang n

author keywords: boronic acid; sensing; sensor; fluorescent; quinoline; pKa; sugar recognition; heterocycles
topics (OpenAlex): Molecular Sensors and Ion Detection; Advanced biosensing and bioanalysis techniques; Porphyrin and Phthalocyanine Chemistry
TL;DR: 5-quinolineboronic acid (5-QBA) is reported that shows significant fluorescent property changes through a unique pKa-switching mechanism upon binding a diol in aqueous solution. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2005 patent

Fluorescent sensor compounds for detecting saccharides

Washington, DC: U.S. Patent and Trademark Office.

By: B. Wang, B. Weston & W. Yang

Source: NC State University Libraries
Added: August 6, 2018

2005 article

Selective elimination of perennial ryegrass by activation of a pro-herbicide through engineering E. coli argE gene

Yang, W., Sivamani, E., Bruneau, A. H., Wang, B., & Qu, R. (2005, May 1). Molecular Breeding.

By: W. Yang n, E. Sivamani n, A. Bruneau n, B. Wang n & R. Qu n

author keywords: argE; N-acetyl-phosphinothricin; perennial ryegrass; phosphinothricin; summer persistence; transgenics
topics (OpenAlex): Plant tissue culture and regeneration; Transgenic Plants and Applications; Plant Virus Research Studies
TL;DR: This approach provides a means to selectively remove a group of transgenic plants without affecting other plants growing with them and to cause self elimination of the plants. (via Semantic Scholar)
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UN Sustainable Development Goal Categories
15. Life on Land (Web of Science)
Source: Web Of Science
Added: August 6, 2018

2004 journal article

A new type of water-soluble fluorescent boronic acid suitable for construction of polyboronic acids for carbohydrate recognition

Heterocyclic Communications, 10(6), 383–388.

By: W. Yang, L. Li & B. Wang

Source: NC State University Libraries
Added: August 6, 2018

2004 article

The effect of substitution patterns on the release rates of opioid peptides DADLE and [Leu5]-enkephalin from coumarin prodrug moieties

Zych, L. A., Yang, W., Liao, Y., Griffin, K. R., & Wang, B. (2004, January 16). Bioorganic Chemistry.

By: L. Zych n, W. Yang n, Y. Liao n, K. Griffin n & B. Wang n

author keywords: coumarin; cyclic prodrug; opioid peptide; esterase; structural effect
MeSH headings : Coumarins / chemistry; Coumarins / metabolism; Enkephalin, Leucine-2-Alanine / analogs & derivatives; Enkephalin, Leucine-2-Alanine / chemical synthesis; Enkephalin, Leucine-2-Alanine / chemistry; Enkephalin, Leucine-2-Alanine / metabolism; Enkephalins / chemical synthesis; Enkephalins / chemistry; Enkephalins / metabolism; Esterases / metabolism; Kinetics; Molecular Structure; Prodrugs / chemical synthesis; Prodrugs / chemistry; Prodrugs / metabolism
topics (OpenAlex): Neuropeptides and Animal Physiology; Receptor Mechanisms and Signaling; Chemical Synthesis and Analysis
TL;DR: Aimed at further understanding the structure-release rate relationship of the coumarin-based cyclic prodrugs, a series of substituted coumarinic acid derivatives of opioid peptides, DADLE, and [Leu(5)]-enkephalin are synthesized and examined. (via Semantic Scholar)
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Source: Web Of Science
Added: August 6, 2018

2003 article

A novel type of fluorescent boronic acid that shows large fluorescence intensity changes upon binding with a carbohydrate in aqueous solution at physiological pH

Yang, W., Yan, J., Springsteen, G., Deeter, S., & Wang, B. (2003, March 1). Bioorganic & Medicinal Chemistry Letters.

By: W. Yang n, J. Yan n, G. Springsteen n, S. Deeter n & B. Wang n

MeSH headings : Boronic Acids / chemical synthesis; Boronic Acids / chemistry; Carbohydrates / chemistry; Fluorescent Dyes / chemical synthesis; Fluorescent Dyes / chemistry; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Quinolines / chemical synthesis; Quinolines / chemistry; Solutions
topics (OpenAlex): Molecular Sensors and Ion Detection; Luminescence and Fluorescent Materials; Lanthanide and Transition Metal Complexes
TL;DR: 8-quinolineboronic acid is reported as a novel type of fluorescent probe for carbohydrates that responds to the binding of a carbohydrate with over 40-fold increases in fluorescence intensity and shows optimal fluorescence change at physiological pH in aqueous solution. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2003 article

Boronic acid compounds as potential pharmaceutical agents

Yang, W., Gao, X., & Wang, B. (2003, February 10). Medicinal Research Reviews.

By: W. Yang n, X. Gao n & B. Wang n

author keywords: boronic acid; enzyme inhibitor; boron neutron; capture agent; antibody mimics; drug delivery
MeSH headings : Acids / chemistry; Acids / pharmacology; Boron Compounds / chemistry; Boron Compounds / pharmacology; Boron Neutron Capture Therapy; Drug Delivery Systems; Enzyme Inhibitors / chemistry; Enzyme Inhibitors / pharmacology; Humans
topics (OpenAlex): Boron Compounds in Chemistry; Organoboron and organosilicon chemistry; Organometallic Complex Synthesis and Catalysis
TL;DR: This study reviews the recent development in boronic acid compounds during the last six years and outlines the priorities for further research into these compounds. (via Semantic Scholar)
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UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2003 article

The first fluorescent sensor for d-glucarate based on the cooperative action of boronic acid and guanidinium groups

Yang, W., Yan, J., Fang, H., & Wang, B. (2003, February 17). Chemical Communications.

By: W. Yang n, J. Yan n, H. Fang n & B. Wang n

MeSH headings : Binding Sites; Biosensing Techniques / methods; Boronic Acids / chemistry; Fluorescent Dyes / chemistry; Glucaric Acid / isolation & purification; Glucaric Acid / metabolism; Guanidine / chemistry; Models, Molecular; Spectrometry, Fluorescence
topics (OpenAlex): Molecular Sensors and Ion Detection; Luminescence and Fluorescent Materials; Sulfur Compounds in Biology
TL;DR: A new fluorescent sensor with a recognition unit consisting of a boronic acid moiety and a guanidinium unit shows selective binding of D-glucarate in aqueous solution. (via Semantic Scholar)
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Source: Web Of Science
Added: August 6, 2018

2002 article

A glucose-selective fluorescence sensor based on boronicacid-diol recognition

Karnati, V. V., Gao, X., Gao, S., Yang, W., Ni, W., Sankar, S., & Wang, B. (2002, December 1). Bioorganic & Medicinal Chemistry Letters.

By: V. Karnati n, X. Gao n, S. Gao n, W. Yang n, W. Ni n, S. Sankar n, B. Wang n

MeSH headings : Biosensing Techniques / methods; Boron Compounds / chemical synthesis; Boron Compounds / chemistry; Fluorescence; Fluorescent Dyes / chemical synthesis; Fluorescent Dyes / chemistry; Glucose / analogs & derivatives; Glucose / analysis; Magnetic Resonance Spectroscopy; Sensitivity and Specificity; Spectrometry, Fluorescence
topics (OpenAlex): Molecular Sensors and Ion Detection; Luminescence and Fluorescent Materials; Analytical Chemistry and Sensors
TL;DR: A glucose selective diphenylboronic acid fluorescent sensor (10a) with a K(a) of 1472M(-1) has been synthesized and evaluated and 1H NMR studies indicate that sensor 10a binds with alpha-D-glucofuranose in a bidentate manner (1:1 ratio). (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2002 article

Catechol pendant polystyrene for solid-phase synthesis

Yang, W., Gao, X., Springsteen, G., & Wang, B. (2002, September 1). Tetrahedron Letters.

By: W. Yang n, X. Gao n, G. Springsteen n & B. Wang n

topics (OpenAlex): Chemical Synthesis and Analysis; Boron Compounds in Chemistry; Organoboron and organosilicon chemistry
TL;DR: The feasibility of using immobilized catechol to capture boronic acid products for purification and solid-phase transformation was demonstrated and the immobilized pendant polystyrene polymer was prepared from the Merrifield resin via a convenient procedure with high-density loading. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2002 article

Diboronic acids as fluorescent probes for cells expressing sialyl lewis X

Yang, W., Gao, S., Gao, X., Karnati, V. V. R., Ni, W., Wang, B., … Weston, B. (2002, August 1). Bioorganic & Medicinal Chemistry Letters.

By: W. Yang n, S. Gao n, X. Gao n, V. Karnati n, W. Ni n, B. Wang n, W. Hooks *, J. Carson*, B. Weston*

MeSH headings : Animals; Binding Sites; Boronic Acids / chemical synthesis; Boronic Acids / chemistry; Boronic Acids / metabolism; COS Cells; Fluorescence; Gene Expression; Humans; Mice; Molecular Structure; Oligosaccharides / analysis; Oligosaccharides / chemistry; Oligosaccharides / genetics; Sialyl Lewis X Antigen; Staining and Labeling / methods; Tumor Cells, Cultured
topics (OpenAlex): Molecular Sensors and Ion Detection; Glycosylation and Glycoproteins Research; Supramolecular Self-Assembly in Materials
TL;DR: A series of fluorescent diboronic acids was synthesized in nine steps as potential sensors for sialyl Lewis X (sLex) and compound 7e was found to show the strongest fluorescence enhancement upon binding with sLex. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

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