Works (11)
Updated: July 5th, 2023 15:59
2005 journal article
A new type of boronic acid fluorescent reporter compound for sugar recognition
TETRAHEDRON LETTERS, 46(46), 7981–7984.
author keywords: boronic acid; sensing; sensor; fluorescent; quinoline; pKa; sugar recognition; heterocycles
TL;DR:
5-quinolineboronic acid (5-QBA) is reported that shows significant fluorescent property changes through a unique pKa-switching mechanism upon binding a diol in aqueous solution.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
6. Clean Water and Sanitation
(OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2005 patent
Fluorescent sensor compounds for detecting saccharides
Washington, DC: U.S. Patent and Trademark Office.
Source: NC State University Libraries
Added: August 6, 2018
2005 journal article
Selective elimination of perennial ryegrass by activation of a pro-herbicide through engineering E-coli argE gene
MOLECULAR BREEDING, 15(4), 339–347.
author keywords: argE; N-acetyl-phosphinothricin; perennial ryegrass; phosphinothricin; summer persistence; transgenics
TL;DR:
This approach provides a means to selectively remove a group of transgenic plants without affecting other plants growing with them and to cause self elimination of the plants.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2004 journal article
A new type of water-soluble fluorescent boronic acid suitable for construction of polyboronic acids for carbohydrate recognition
Heterocyclic Communications, 10(6), 383–388.
Source: NC State University Libraries
Added: August 6, 2018
2004 journal article
The effect of substitution patterns on the release rates of opioid peptides DADLE and [Leu(5)]-enkephalin from coumarin prodrug moieties
BIOORGANIC CHEMISTRY, 32(2), 109–123.
author keywords: coumarin; cyclic prodrug; opioid peptide; esterase; structural effect
MeSH headings : Coumarins / chemistry; Coumarins / metabolism; Enkephalin, Leucine-2-Alanine / analogs & derivatives; Enkephalin, Leucine-2-Alanine / chemical synthesis; Enkephalin, Leucine-2-Alanine / chemistry; Enkephalin, Leucine-2-Alanine / metabolism; Enkephalins / chemical synthesis; Enkephalins / chemistry; Enkephalins / metabolism; Esterases / metabolism; Kinetics; Molecular Structure; Prodrugs / chemical synthesis; Prodrugs / chemistry; Prodrugs / metabolism
TL;DR:
Aimed at further understanding the structure-release rate relationship of the coumarin-based cyclic prodrugs, a series of substituted coumarinic acid derivatives of opioid peptides, DADLE, and [Leu(5)]-enkephalin are synthesized and examined.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2003 journal article
A novel type of fluorescent boronic acid that shows large fluorescence intensity changes upon binding with a carbohydrate in aqueous solution at physiological pH
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 13(6), 1019–1022.
MeSH headings : Boronic Acids / chemical synthesis; Boronic Acids / chemistry; Carbohydrates / chemistry; Fluorescent Dyes / chemical synthesis; Fluorescent Dyes / chemistry; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Quinolines / chemical synthesis; Quinolines / chemistry; Solutions
TL;DR:
8-quinolineboronic acid is reported as a novel type of fluorescent probe for carbohydrates that responds to the binding of a carbohydrate with over 40-fold increases in fluorescence intensity and shows optimal fluorescence change at physiological pH in aqueous solution.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
6. Clean Water and Sanitation
(OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2003 review
Boronic acid compounds as potential pharmaceutical agents
[Review of ]. MEDICINAL RESEARCH REVIEWS, 23(3), 346–368.
author keywords: boronic acid; enzyme inhibitor; boron neutron; capture agent; antibody mimics; drug delivery
MeSH headings : Acids / chemistry; Acids / pharmacology; Boron Compounds / chemistry; Boron Compounds / pharmacology; Boron Neutron Capture Therapy; Drug Delivery Systems; Enzyme Inhibitors / chemistry; Enzyme Inhibitors / pharmacology; Humans
TL;DR:
This study reviews the recent development in boronic acid compounds during the last six years and outlines the priorities for further research into these compounds.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2003 journal article
The first fluorescent sensor for D-glucarate based on the cooperative action of boronic acid and guanidinium groups
CHEMICAL COMMUNICATIONS, (6), 792–793.
MeSH headings : Binding Sites; Biosensing Techniques / methods; Boronic Acids / chemistry; Fluorescent Dyes / chemistry; Glucaric Acid / isolation & purification; Glucaric Acid / metabolism; Guanidine / chemistry; Models, Molecular; Spectrometry, Fluorescence
TL;DR:
A new fluorescent sensor with a recognition unit consisting of a boronic acid moiety and a guanidinium unit shows selective binding of D-glucarate in aqueous solution.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2002 journal article
A glucose-selective fluorescence sensor based on boronic acid-diol recognition
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 12(23), 3373–3377.
MeSH headings : Biosensing Techniques / methods; Boron Compounds / chemical synthesis; Boron Compounds / chemistry; Fluorescence; Fluorescent Dyes / chemical synthesis; Fluorescent Dyes / chemistry; Glucose / analogs & derivatives; Glucose / analysis; Magnetic Resonance Spectroscopy; Sensitivity and Specificity; Spectrometry, Fluorescence
TL;DR:
A glucose selective diphenylboronic acid fluorescent sensor (10a) with a K(a) of 1472M(-1) has been synthesized and evaluated and 1H NMR studies indicate that sensor 10a binds with alpha-D-glucofuranose in a bidentate manner (1:1 ratio).
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2002 journal article
Catechol pendant polystyrene for solid-phase synthesis
TETRAHEDRON LETTERS, 43(36), 6339–6342.
TL;DR:
The feasibility of using immobilized catechol to capture boronic acid products for purification and solid-phase transformation was demonstrated and the immobilized pendant polystyrene polymer was prepared from the Merrifield resin via a convenient procedure with high-density loading.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
6. Clean Water and Sanitation
(OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2002 journal article
Diboronic acids as fluorescent probes for cells expressing sialyl Lewis X
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 12(16), 2175–2177.
MeSH headings : Animals; Binding Sites; Boronic Acids / chemical synthesis; Boronic Acids / chemistry; Boronic Acids / metabolism; COS Cells; Fluorescence; Gene Expression; Humans; Mice; Molecular Structure; Oligosaccharides / analysis; Oligosaccharides / chemistry; Oligosaccharides / genetics; Sialyl Lewis X Antigen; Staining and Labeling / methods; Tumor Cells, Cultured
TL;DR:
A series of fluorescent diboronic acids was synthesized in nine steps as potential sensors for sialyl Lewis X (sLex) and compound 7e was found to show the strongest fluorescence enhancement upon binding with sLex.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
6. Clean Water and Sanitation
(OpenAlex)
Source: Web Of Science
Added: August 6, 2018
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