@misc{yang_gao_wang_2003, title={Boronic acid compounds as potential pharmaceutical agents}, volume={23}, ISSN={["1098-1128"]}, DOI={10.1002/med.10043}, abstractNote={Abstract}, number={3}, journal={MEDICINAL RESEARCH REVIEWS}, author={Yang, WQ and Gao, XM and Wang, BH}, year={2003}, month={May}, pages={346–368} } @article{karnati_gao_gao_yang_ni_sankar_wang_2002, title={A glucose-selective fluorescence sensor based on boronic acid-diol recognition}, volume={12}, ISSN={["0960-894X"]}, DOI={10.1016/S0960-894X(02)00767-9}, abstractNote={A glucose selective diphenylboronic acid fluorescent sensor (10a) with a K(a) of 1472M(-1) has been synthesized and evaluated. This sensor shows a 43- and 49-fold selectivity for glucose over fructose and galactose, respectively. The binding affinity improvement is about 300-fold and the selectivity improvement for glucose over fructose is about 1400-fold compared with the monoboronic acid compound, phenylboronic acid. 1H NMR studies indicate that sensor 10a binds with alpha-D-glucofuranose in a bidentate manner (1:1 ratio).}, number={23}, journal={BIOORGANIC & MEDICINAL CHEMISTRY LETTERS}, author={Karnati, VV and Gao, XM and Gao, SH and Yang, WQ and Ni, WJ and Sankar, S and Wang, BH}, year={2002}, month={Dec}, pages={3373–3377} } @misc{wang_gao_wang_2002, title={Boronic acid-based sensors}, volume={6}, ISSN={["1875-5348"]}, DOI={10.2174/1385272023373446}, abstractNote={There has been a great deal of interest in recent years in using boronic acid as the recognition motif for the development of sensors. Because boronic acids can form tight and reversible complexes with diol compounds such as carbohydrates, the majority of the efforts, led by the Shinkai group, have been on the development of sensors for carbohydrates. Boronic acids are also known to selectively recognize fluoride among halides and other anions. Therefore, there have also been efforts in using boronic acid compounds for the development fluoride sensors. This paper reviews the progress in this field during the last five years. Keywords: Boronic, Acid-Based Sensors}, number={14}, journal={CURRENT ORGANIC CHEMISTRY}, author={Wang, W and Gao, XM and Wang, BH}, year={2002}, month={Dec}, pages={1285–1317} } @article{yang_gao_springsteen_wang_2002, title={Catechol pendant polystyrene for solid-phase synthesis}, volume={43}, ISSN={["0040-4039"]}, DOI={10.1016/S0040-4039(02)01370-9}, abstractNote={A catechol pendant polystyrene polymer was prepared from the Merrifield resin via a convenient procedure with high-density loading. Due to the high affinity binding between catechol and boronic acid, the polymer resin readily captures boronic acid compounds. The feasibility of using immobilized catechol to capture boronic acid products for purification and solid-phase transformation was demonstrated. Moreover, the immobilized catechol was also used for the preparation of resin-bound catecholborane, which can be used as a solid-phase amidation reagent.}, number={36}, journal={TETRAHEDRON LETTERS}, author={Yang, WQ and Gao, XM and Springsteen, G and Wang, BH}, year={2002}, month={Sep}, pages={6339–6342} } @article{yang_gao_gao_karnati_ni_wang_hooks_carson_weston_2002, title={Diboronic acids as fluorescent probes for cells expressing sialyl Lewis X}, volume={12}, ISSN={["0960-894X"]}, DOI={10.1016/S0960-894X(02)00339-6}, abstractNote={A series of fluorescent diboronic acids was synthesized in nine steps as potential sensors for sialyl Lewis X (sLex). The fluorescent binding studies of these sensors with sLex were carried out in a mixed aqueous solution. Compound 7e was found to show the strongest fluorescence enhancement upon binding with sLex. Using cell cultures, 7e was shown to label sLex-expressing HEPG2 cells at 1 microM, while non-sLex-expressing cells were not labeled.}, number={16}, journal={BIOORGANIC & MEDICINAL CHEMISTRY LETTERS}, author={Yang, WQ and Gao, SH and Gao, XM and Karnati, VVR and Ni, WJ and Wang, BH and Hooks, WB and Carson, J and Weston, B}, year={2002}, month={Aug}, pages={2175–2177} }