Nyla Dil

Works (2)

Updated: July 5th, 2023 15:59

2003 article

Interleukin-1β does not contribute to genetic strain-based differences in iNOS expression and activity in chicken macrophages

Dil, N., & Qureshi, M. A. (2003, February 1). Developmental & Comparative Immunology.

By: N. Dil* & M. Qureshi n

author keywords: macrophage; lipopolysaccharide; inducible nitric oxide synthase; IL-1 beta; IL-1R(1); PCR; chicken; genetic lines
MeSH headings : Animals; Chickens; Interleukin-1 / genetics; Interleukin-1 / physiology; Lipopolysaccharides / pharmacology; Macrophages / drug effects; Macrophages / enzymology; Nitric Oxide Synthase / genetics; Nitric Oxide Synthase Type II; Nitrites / metabolism; RNA, Messenger / analysis; Receptors, Interleukin-1 / analysis; Receptors, Interleukin-1 / physiology; Species Specificity
topics (OpenAlex): Animal Nutrition and Physiology; Peroxisome Proliferator-Activated Receptors; Nitric Oxide and Endothelin Effects
TL;DR: Observations suggest that IL-1beta is involved in mediating LPS-induced iNOS expression and activity, and the differential response of GB1 and K-strain macrophages in terms of LPS/iNOSexpression and activity is unlikely to be modulated by IL- 1beta. (via Semantic Scholar)
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Added: August 6, 2018

2002 article

Involvement of lipopolysaccharide related receptors and nuclear factor κB in differential expression of inducible nitric oxide synthase in chicken macrophages from different genetic backgrounds

Dil, N., & Qureshi, M. A. (2002, September 1). Veterinary Immunology and Immunopathology.

By: N. Dil n & M. Qureshi n

author keywords: chicken macrophage; genetic lines; iNOS; CD14; TLR4; NF kappa B
MeSH headings : Animals; Chickens / genetics; Chickens / immunology; Drosophila Proteins; Enzyme Induction / drug effects; Flow Cytometry; Gene Expression Regulation, Enzymologic / drug effects; Lipopolysaccharide Receptors / biosynthesis; Lipopolysaccharide Receptors / genetics; Lipopolysaccharide Receptors / metabolism; Lipopolysaccharides / pharmacology; Macrophages / drug effects; Macrophages / enzymology; Macrophages / metabolism; Membrane Glycoproteins / biosynthesis; Membrane Glycoproteins / metabolism; NF-kappa B / antagonists & inhibitors; NF-kappa B / metabolism; Nitric Oxide Synthase / biosynthesis; Nitric Oxide Synthase / drug effects; Nitric Oxide Synthase / genetics; Nitric Oxide Synthase Type II; Nitrites / metabolism; Receptors, Cell Surface / biosynthesis; Receptors, Cell Surface / metabolism; Signal Transduction / drug effects; Toll-Like Receptor 4; Toll-Like Receptors; Transcriptional Activation
topics (OpenAlex): Immune Response and Inflammation; Nitric Oxide and Endothelin Effects; Peroxisome Proliferator-Activated Receptors
TL;DR: A differential and perhaps more stronger LPS-mediated signaling via CD14, TLR4 and NF kappa B is responsible for the heightened iNOS gene induction in K-strain (hyper- responder) macrophages than in GB2 (hypo-responder) chickens. (via Semantic Scholar)
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UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

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