Works (3)

Updated: July 9th, 2023 19:05

2007 journal article

The appendage role of insect disco genes and possible implications on the evolution of the maggot larval form

DEVELOPMENTAL BIOLOGY, 309(1), 56–69.

By: M. Patel n, L. Farzana n, L. Robertson n, J. Hutchinson n, N. Grubbs n, M. Shepherd n, J. Mahaffey n

author keywords: drosophila; segment identity; zinc finger; appendage; limb; pattern formation
MeSH headings : Animals; Biological Evolution; Body Patterning; DNA-Binding Proteins / metabolism; Drosophila / embryology; Drosophila / growth & development; Drosophila / metabolism; Drosophila Proteins / metabolism; Head / embryology; Head / growth & development; Larva / growth & development; Larva / metabolism; Transcription Factors / metabolism; Tribolium / embryology; Tribolium / growth & development; Tribolium / metabolism
TL;DR: It is proposed that the disco genes always function as appendage factors, but their appendage nature is masked during Drosophila embryogenesis due to the reduction of limb fields in the maggot style Drosophile larva. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2004 journal article

An interactive network of zinc-finger proteins contributes to regionalization of the Drosophila embryo and establishes the domains of HOM-C protein function

DEVELOPMENT, 131(12), 2781–2789.

By: L. Robertson n, D. Bowling n, J. Mahaffey n, B. Imiolczyk n & J. Mahaffey n

author keywords: Hex; homeotic; zinc finger; Drosophila; segment identity; pattern formation
MeSH headings : Animals; Body Patterning / physiology; DNA-Binding Proteins / genetics; Drosophila Proteins / genetics; Drosophila melanogaster / embryology; Embryo, Nonmammalian / physiology; Gene Expression Regulation, Developmental / genetics; Homeodomain Proteins / genetics; Morphogenesis / physiology; Repressor Proteins / genetics; Transcription Factors / genetics; Zinc Fingers / physiology
TL;DR: It is concluded that a combination of regionalizing factors, in concert with the HOM-C proteins, promotes the specification of individual segment identity. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2002 journal article

Expression of the Drosophila gene disconnected using the UAS/GAL4 system

GENESIS, 34(1-2), 103–106.

By: L. Robertson n, B. Dey*, A. Campos* & J. Mahaffey n

MeSH headings : Animals; Animals, Genetically Modified; Armadillo Domain Proteins; DNA Transposable Elements; DNA-Binding Proteins / biosynthesis; DNA-Binding Proteins / genetics; Drosophila Proteins / genetics; Drosophila melanogaster / embryology; Drosophila melanogaster / genetics; Enhancer Elements, Genetic; Eye / embryology; Female; Homeodomain Proteins / genetics; Male; Mutation; Saccharomyces cerevisiae Proteins / genetics; Trans-Activators / genetics; Transcription Factors / biosynthesis; Transcription Factors / genetics
TL;DR: Three UAS-disco constructs were generated—two encoding wildtype proteins and one producing an altered protein like that encoded by the disco null allele, which causes embryonic lethality and the absence of some larval mouth structures arising from the gnathocephalic segments. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

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