2002 journal article

A factorial design to optimize cell-based drug discovery analysis

JOURNAL OF CHEMICAL INFORMATION AND COMPUTER SCIENCES, 42(5), 1221–1229.

MeSH headings : Anti-HIV Agents / chemistry; Anti-HIV Agents / pharmacology; Cells; Computer Simulation; Databases, Factual; Drug Design; Drug Evaluation, Preclinical / statistics & numerical data; Humans; Microbial Sensitivity Tests / statistics & numerical data; Quantitative Structure-Activity Relationship
TL;DR: A fractional factorial design is implemented to evaluate the effects of potentially influential factors in the cell-based approach, and lift chart results show that the design scheme is able to find conditions that enhance hit rates. (via Semantic Scholar)
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