2009 journal article

SNP Selection and Multidimensional Scaling to Quantify Population Structure

GENETIC EPIDEMIOLOGY, 33(6), 488–496.

By: K. Miclaus n, R. Wolfinger* & W. Czika*

author keywords: population stratification; substructure-informative SNP selection; Hardy-Weinberg disequilibrium; nonmetric MDS; association studies
MeSH headings : Algorithms; Genetic Markers; Genetics, Population / methods; Genome-Wide Association Study; Humans; Polymorphism, Single Nucleotide; Selection, Genetic
TL;DR: This work develops methodology for single nucleotide polymorphism (SNP) selection and subsequent population stratification visualization based on deviation from Hardy‐Weinberg equilibrium in conjunction with non‐metric multidimensional scaling (MDS); a distance‐based multivariate technique. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2004 journal article

Properties of the multiallelic trend test

BIOMETRICS, 60(1), 69–74.

By: W. Czika* & B. Weir n

author keywords: case-control test; multiallelic markers; nongametic linkage disequilibrium
MeSH headings : Alleles; Biometry; Case-Control Studies; Chi-Square Distribution; Genetic Markers; Humans; Linkage Disequilibrium; Models, Genetic
TL;DR: It is shown here that the multiple‐allele version of Armitage's trend test has increased power over the two‐alleel version under the requirement of equifrequent alleles, but not in general. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2002 personal communication

Using all alleles in the multiallelic versions of the SDT and combined SDT/TDT

By: W. Czika & J. Berry

Source: NC State University Libraries
Added: August 6, 2018

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