2004 journal article

Use of regression methods to identify motifs that modulate germline transcription in Drosophila melanogaster

GENETICS RESEARCH, 83(3), 177–188.

By: E. Honeycutt n & G. Gibson n

MeSH headings : Animals; Binding Sites / genetics; DNA / genetics; DNA / metabolism; Decision Trees; Drosophila melanogaster / genetics; Gene Expression Regulation / genetics; Linear Models; Models, Genetic; Regression Analysis; Regulatory Sequences, Nucleic Acid / genetics; Sex Factors; Transcription Factors / genetics; Transcription Factors / metabolism
TL;DR: A regression tree model provides a grouping of independent variables into multiple linear models, an advantage over a single multivariate model, and suggests binding sites for cooperating factors in sex-specific expression, as well as a way of combining smaller motifs into larger binding sites. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2002 journal article

The evolution of developmental regulatory pathways

CURRENT OPINION IN GENETICS & DEVELOPMENT, 12(6), 695–700.

By: G. Gibson n & E. Honeycutt

MeSH headings : Animals; Biological Evolution; Gene Expression Regulation, Developmental; Genes, Regulator; Humans; Phylogeny
TL;DR: notation of the fission yeast, rice, and mouse genomes confirms that most regulatory families are shared among eukaryotes but also shows that certain gene families have restricted distributions. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

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