Works (10)
Updated: July 5th, 2023 16:04
2002 journal article
Lactoferrin gene expression is estrogen responsive in human and rhesus monkey endometrium
MOLECULAR HUMAN REPRODUCTION, 8(1), 58–67.
author keywords: endometrium; estrogen response element; human and monkey; lactoferrin; lactoferrin gene promoter
MeSH headings : Adult; Aged; Animals; Endometrium / cytology; Endometrium / metabolism; Estrogen Receptor alpha; Estrogens / physiology; Female; Gene Expression Regulation; Humans; Lactoferrin / genetics; Lactoferrin / metabolism; Macaca mulatta / physiology; Male; Menstrual Cycle / physiology; Middle Aged; Milk / chemistry; Ovariectomy; Promoter Regions, Genetic; Prostate / drug effects; Prostate / metabolism; Receptors, Estrogen / metabolism; Response Elements; Steroidogenic Factor 1
TL;DR:
It is shown that lactoferrin gene expression is responsive to estrogen in primate endometrium and forms two complexes in an electrophoresis mobility shift assay (EMSA) that could be supershifted by an antibody to ERalpha.
(via Semantic Scholar)
academic.oup.com (publisher PDF)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2001 journal article
Differential activation of MAPK during Mullerian duct growth and apoptosis: JNK and p38 stimulation by DES blocks tissue death
CELL AND TISSUE RESEARCH, 306(1), 27–34.
author keywords: Mullerian duct; apoptosis; mitogen-activated protein kinases; c-jun N-terminal kinase; p38; extracellular signal-regulated kinases; diethylstilbestrol; chicken (White Leghorn)
MeSH headings : Animals; Apoptosis / drug effects; Blotting, Western; Chick Embryo; Diethylstilbestrol / pharmacology; Enzyme Activation / drug effects; JNK Mitogen-Activated Protein Kinases; Mitogen-Activated Protein Kinases / metabolism; Mullerian Ducts / cytology; Mullerian Ducts / drug effects; Mullerian Ducts / embryology; Mullerian Ducts / enzymology; p38 Mitogen-Activated Protein Kinases
TL;DR:
Results showed that differential activation of MAPKs existed in the LMD and RMD, and the apoptotic death of RMD was prevented by in vivo diethylstilbestrol treatment, which restored the level of JNK, p-JNK, and p38.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2001 conference paper
JNK modulates the effect of Bcl-2 on the growth or apoptosis of chick Mullerian ducts
Molecular Biology of the Cell, 12(2001 Nov), 124.
Source: NC State University Libraries
Added: August 6, 2018
2000 journal article
Differential expression of c-Jun proteins during Mullerian duct growth and apoptosis: caspase-related tissue death blocked by diethylstilbestrol
CELL AND TISSUE RESEARCH, 302(3), 377–385.
author keywords: Mullerian duct; apoptosis; c-Jun proteins; caspase; diethylstilbestrol; chicken (White leghorn)
MeSH headings : Animals; Apoptosis / drug effects; Blotting, Western; Caspase 3; Caspases / metabolism; Cell Nucleus / ultrastructure; Chick Embryo; DNA Fragmentation / drug effects; Diethylstilbestrol / pharmacology; Electrophoresis, Polyacrylamide Gel; Female; Gene Expression / drug effects; Mullerian Ducts / drug effects; Mullerian Ducts / growth & development; Mullerian Ducts / metabolism; Protein Isoforms / biosynthesis; Protein Isoforms / physiology; Proto-Oncogene Proteins c-jun / biosynthesis; Proto-Oncogene Proteins c-jun / physiology
TL;DR:
High caspase-3 activity (determined by the measurement of the fragmented 85-kDa poly ADP-ribose polymerase) was found in the RMD during apoptosis, and the apoptotic death of RMD was prevented by in vivo diethylstilbestrol treatment, which inhibited the overexpression of the 66-k Da and 45-k da proteins, the fragmentation of DNA, andThe activity of casp enzyme-3.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2000 journal article
Protooncogenes as mediators of apoptosis
International Review of Cytology, 197(2000), 137–202.
Source: NC State University Libraries
Added: August 6, 2018
1998 journal article
Biphasic c-Myc protein expression during gossypol-induced apoptosis in rat spermatocytes
CONTRACEPTION, 57(2), 117–123.
author keywords: gossypol exposure; spermatocyte apoptosis; Western immunoblot; digital imaging analysis; c-Myc expression
MeSH headings : Animals; Apoptosis; Blotting, Western; Culture Techniques; Electrophoresis, Polyacrylamide Gel; Gossypol / pharmacology; Kinetics; Male; Proto-Oncogene Proteins c-myc / metabolism; Rats; Rats, Wistar; Spermatozoa / cytology; Spermatozoa / drug effects; Spermatozoa / metabolism; Testis / drug effects; Testis / metabolism
TL;DR:
Results suggest that spermatocyte apoptosis induced by gossypol is correlated with biphasic c-Myc protein expression, and some hypothetical models are presented to explain c- myc protein-mediated apoptosis.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
1998 journal article
c-fos protein expression in apoptotic rat spermatocytes induced by gossypol
CONTRACEPTION, 57(4), 281–286.
author keywords: gossypol exposure; spermatocyte apoptosis; Western immunoblot; digital imaging analysis; c-fos expression
MeSH headings : Animals; Apoptosis / physiology; Blotting, Western; Cells, Cultured; Down-Regulation; Electrophoresis, Polyacrylamide Gel; Gossypol / pharmacology; Humans; Image Processing, Computer-Assisted; Male; Proto-Oncogene Mas; Proto-Oncogene Proteins c-fos / analysis; Proto-Oncogene Proteins c-fos / genetics; Proto-Oncogene Proteins c-fos / metabolism; Rats; Rats, Wistar; Spermatocytes / cytology; Spermatocytes / metabolism; Spermatocytes / ultrastructure; Up-Regulation
TL;DR:
Results suggest that spermatocyte apoptosis induced by gossypol correlates with biphasic c-fos protein-mediated apoptosis.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
1997 journal article
Reversible changes in the content of cellular and microtubular tubulin in spermatogenic cells after gossypol treatment
CONTRACEPTION, 55(1), 41–46.
author keywords: gossypol treatment; spermatid; spermatocyte; beta-tubulin content; sperm motility
MeSH headings : Animals; Antibodies, Monoclonal / immunology; Enzyme-Linked Immunosorbent Assay; Gossypol / pharmacology; Humans; Male; Microtubules / chemistry; Microtubules / drug effects; Microtubules / metabolism; Radioimmunoassay; Rats; Rats, Wistar; Spermatids / chemistry; Spermatids / drug effects; Spermatids / metabolism; Spermatocytes / chemistry; Spermatocytes / drug effects; Spermatocytes / metabolism; Time Factors; Tubulin / analysis; Tubulin / drug effects; Tubulin / isolation & purification; Tubulin / metabolism
TL;DR:
The results indicated that the tubulins associated with sperMatids were more vulnerable to gossypol than that of the spermatocytes.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(Web of Science)
3. Good Health and Well-being
(OpenAlex)
13. Climate Action
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
1993 journal article
BIOLOGICAL-ACTIVITY IN THE REPOPULATING RAT SPERMATOCYTE AFTER THE WITHDRAWAL OF GOSSYPOL TREATMENT .4. THE ACTIVITY FOR THE MODIFICATION OF CORE HISTONES
CONTRACEPTION, 48(2), 168–177.
author keywords: GOSSYPOL TREATMENT; REPOPULATING SPERMATOCYTE; CORE HISTONES; HISTONE ACETYLATION; HISTONE ACETYLASE ACTIVITY
MeSH headings : Acetylation; Acetylesterase / metabolism; Animals; Cell Nucleus / drug effects; Cell Nucleus / metabolism; Gene Expression; Gossypol / pharmacology; Histones / drug effects; Histones / metabolism; Male; Rats; Rats, Wistar; Spermatocytes / drug effects
TL;DR:
It has been concluded that after gossypol treatment, the activity for nucleosomal core histones acetylation was selectively inhibited, related to an inhibitory effect on the histone acetylase activity.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
1991 personal communication
CORRELATION OF PLASMA GROWTH-HORMONE LEVEL WITH WASTING SYNDROME IN FELINE AIDS
TENG, C. S. (1991, December).
MeSH headings : Animals; Cats; Feline Acquired Immunodeficiency Syndrome / blood; Feline Acquired Immunodeficiency Syndrome / physiopathology; Growth Hormone / blood; Immunohistochemistry; Radioimmunoassay; Specific Pathogen-Free Organisms
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
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