@article{garden_kidd_mexas_chang_jeffery_blois_fogle_macneill_lubas_birkenheuer_et al._2019, title={ACVIM consensus statement on the diagnosis of immune-mediated hemolytic anemia in dogs and cats}, volume={33}, ISSN={["1939-1676"]}, DOI={10.1111/jvim.15441}, abstractNote={Immune‐mediated hemolytic anemia (IMHA) is an important cause of morbidity and mortality in dogs. IMHA also occurs in cats, although less commonly. IMHA is considered secondary when it can be attributed to an underlying disease, and as primary (idiopathic) if no cause is found. Eliminating diseases that cause IMHA may attenuate or stop immune‐mediated erythrocyte destruction, and adverse consequences of long‐term immunosuppressive treatment can be avoided. Infections, cancer, drugs, vaccines, and inflammatory processes may be underlying causes of IMHA. Evidence for these comorbidities has not been systematically evaluated, rendering evidence‐based decisions difficult. We identified and extracted data from studies published in the veterinary literature and developed a novel tool for evaluation of evidence quality, using it to assess study design, diagnostic criteria for IMHA, comorbidities, and causality. Succinct evidence summary statements were written, along with screening recommendations. Statements were refined by conducting 3 iterations of Delphi review with panel and task force members. Commentary was solicited from several professional bodies to maximize clinical applicability before the recommendations were submitted. The resulting document is intended to provide clinical guidelines for diagnosis of, and underlying disease screening for, IMHA in dogs and cats. These should be implemented with consideration of animal, owner, and geographical factors.}, number={2}, journal={JOURNAL OF VETERINARY INTERNAL MEDICINE}, author={Garden, Oliver A. and Kidd, Linda and Mexas, Angela M. and Chang, Yu-Mei and Jeffery, Unity and Blois, Shauna L. and Fogle, Jonathan E. and MacNeill, Amy L. and Lubas, George and Birkenheuer, Adam and et al.}, year={2019}, pages={313–334} }
 @article{kidd_maggi_diniz_hegarty_tucker_breitschwerdt_2008, title={Evaluation of conventional and real-time PCR assays for detection and differentiation of Spotted Fever Group Rickettsia in dog blood}, volume={129}, ISSN={0378-1135}, url={http://dx.doi.org/10.1016/j.vetmic.2007.11.035}, DOI={10.1016/j.vetmic.2007.11.035}, abstractNote={Spotted Fever Group Rickettsia is important cause of emerging and re-emerging infectious disease in people and dogs. Importantly, dogs can serve as sentinels for disease in people. Sensitive and specific diagnostic tests that differentiate among species of infecting Rickettsia are needed. The objective of this study was to develop a sensitive and specific PCR that differentiates SFG Rickettsia infecting dog blood. Conventional and real-time PCR assays were developed using primers that targeted a small region of the ompA gene. Their sensitivity, determined by testing a cloned target sequence in the presence of host DNA, was 15–30 and 5 copies of DNA, respectively. Testing of Rickettsia cultures and analysis of Rickettsia gene sequences deposited in GenBank verified DNA could be amplified and used to differentiate species. DNA from the blood of infected dogs was also tested. Importantly, Rickettsia DNA was detected before seroconversion in some dogs. The species of infecting Rickettsia was also identified. We conclude these assays may assist in the timely diagnosis of infection with SFG Rickettsia. They may also facilitate the discovery of novel SFG Rickettsia infecting dogs, and in the investigation of dogs as sentinels for emerging rickettsioses.}, number={3-4}, journal={Veterinary Microbiology}, publisher={Elsevier BV}, author={Kidd, L. and Maggi, R. and Diniz, P.P.V.P. and Hegarty, B. and Tucker, M. and Breitschwerdt, E.}, year={2008}, month={Jun}, pages={294–303} }
 @article{solano-gallego_kidd_trotta_di marco_caldin_furlanello_breitschwerdt_2006, title={Febrile Illness Associated with Rickettsia conorii Infection in Dogs from Sicily}, volume={12}, ISSN={1080-6040}, url={http://dx.doi.org/10.3201/eid1212.060326}, DOI={10.3201/eid1212.060326}, abstractNote={We report serologic and molecular evidence of acute, febrile illness associated with Rickettsia conorii in 3 male Yorkshire terriers from Sicily (Italy).}, number={12}, journal={Emerging Infectious Diseases}, publisher={Centers for Disease Control and Prevention (CDC)}, author={Solano-Gallego, Laia and Kidd, Linda and Trotta, Michele and Di Marco, Marco and Caldin, Marco and Furlanello, Tommaso and Breitschwerdt, Edward}, year={2006}, pages={1985–1988} }
 @article{osmond_marcellin-little_harrysson_kidd_2006, title={Morphometric assessment of the proximal portion of the tibia in dogs with and without cranial cruciate ligament rupture}, volume={47}, ISSN={["1740-8261"]}, DOI={10.1111/j.1740-8261.2006.00119.x}, abstractNote={Based on the clinical observation that dogs with a steep tibial plateau slope had variable tibial morphology, we hypothesized that these dogs could be further characterized using measurements developed by examining computer generated models of specific proximal tibial malformations. A 3D tibial model was created from a normal canine tibia. The model was manipulated to reproduce two specific proximal tibial anomalies representing deformities originating from the tibial plateau or the proximal tibial shaft. Data from these models were used to create specific measurements that would characterize the shape of these anomalies. These measurements included the diaphyseal tibial axis (DTA)/proximal tibial axis (PTA) angle, which defined the orientation of the proximal portion of the shaft in relation to the tibial mid-shaft. These measurements were then made on radiographs of dogs with and without cranial cruciate ligament (CCL) rupture. Models with tibial plateau and proximal shaft deformities had a steep tibial plateau slope (TPS). Models with proximal shaft deformity had a markedly increased DTA/PTA angle. The model with a 10 degree proximal shaft deformity had a DTA/PTA angle of 11.23 degrees. Six dogs (9.0%) had a DTA/PTA angle larger than 11.23 degrees (range, 11.4-13.9 degrees). Dogs in this group had ruptured CCL and a steep TPS. Dogs with CCL rupture had higher TPS (mean, 31.8 +/- 4.1 degrees) and DTA/PTA angle (mean, 6.0 +/- 3.3 degrees) than dogs without CCL rupture (means, 23.6 +/- 3.4 degrees and 4.1 +/- 2.2 degrees, respectively). Dogs with proximal shaft deformity represented a distinct group, which could not be identified using the magnitude of the TPS alone. Characterizing more precisely the shape of the proximal portion of the tibia in dogs contributes to our understanding of the pathogenesis of steep TPS and may facilitate the optimization of the surgical management of dogs with CCL rupture.}, number={2}, journal={VETERINARY RADIOLOGY & ULTRASOUND}, author={Osmond, CS and Marcellin-Little, DJ and Harrysson, OLA and Kidd, LB}, year={2006}, pages={136–141} }
 @article{kidd_salavaggione_szumlanski_miller_weinshilboum_trepanier_2004, title={Thiopurine methyltransferase activity in red blood cells of dogs}, volume={18}, ISSN={["1939-1676"]}, DOI={10.1892/0891-6640(2004)18<214:TMAIRB>2.0.CO;2}, abstractNote={Thiopurine methyltransferase (TPMT) is an important enzyme in the metabolism of thiopurine medications such as azathioprine. In humans, activity varies widely among individuals, primarily because of genetic polymorphisms. Low TPMT activity increases the risk of myelosuppression from azathioprine and 6-mercaptopurine, whereas high TPMT activity is associated with poor drug efficacy. The purpose of this study was to determine whether dogs also show a wide range of TPMT activity. Heparinized blood samples were obtained from 177 dogs associated with a veterinary teaching hospital. Red blood cell (RBC) TPMT activity was measured by means of a modification of a radiochemical method as established for use in people. TPMT activity varied across a 9-fold range (7.9-71.8 U of RBC per milliliter; median, 21.7). Variation in TPMT activity was not associated with age, sex, or neutering status. Giant Schnauzers had much lower TPMT activity (7.9-20 U of RBC per milliliter; median, 13.1; P < .001) than did other breeds, and Alaskan Malamutes had much higher TPMT activity (22.7-71.8 U of RBC per milliliter; median, 36.0; P < .001) than did other breeds. Such variations in TPMT activity in the canine population and within groups of related dogs could affect thiopurine drug toxicity and efficacy in canine patients.}, number={2}, journal={JOURNAL OF VETERINARY INTERNAL MEDICINE}, author={Kidd, LB and Salavaggione, OE and Szumlanski, CL and Miller, JL and Weinshilboum, RA and Trepanier, L}, year={2004}, pages={214–218} }
 @article{kidd_breitschwerdt_2003, title={Transmission times and prevention of tick-borne diseases in dogs}, volume={25}, number={10}, journal={Compendium on Continuing Education for the Practicing Veterinarian}, author={Kidd, L. and Breitschwerdt, E. B.}, year={2003}, pages={742-} }