Epigenetic and Genomic Imprinting Analysis in Nuclear Transfer Derived Bos gaurus/Bos taurus Hybrid Fetuses1
Dindot, S. V., Farin, P. W., Farin, C. E., Romano, J., Walker, S., Long, C., & Piedrahita, J. A. (2004, August 1). Biology of Reproduction, Vol. 71, pp. 470–478.
MeSH headings : Animals; Cattle; Chimera / genetics; Cloning, Organism; DNA Methylation; DNA, Satellite; Embryonic Development; Epidermis / physiology; Epigenesis, Genetic / genetics; Exons; Female; Fibroblasts / physiology; Genomic Imprinting / genetics; Genotype; Insulin-Like Growth Factor II / genetics; Keratins / genetics; Nuclear Transfer Techniques; Placenta; Pregnancy; Promoter Regions, Genetic; Proteins / genetics; RNA, Long Noncoding; RNA, Untranslated / genetics
topics (OpenAlex): Reproductive Biology and Fertility; Prenatal Screening and Diagnostics; Genetic Syndromes and Imprinting
TL;DR:
The use of a bovine interspecies model for the assessment and characterization of epigenetic modifications and genomic imprinting in Day 40-old female NT-derived fetuses and placenta indicates that the nuclear transfer process affects gene expression patterns in the trophectoderm- and inner cell mass-derived tissues to different extents.
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