Works (1)
Updated: July 5th, 2023 15:58
2004 journal article
The infant mouse as a in vivo model for the detection and study of DNA damage-induced changes in the liver
MOLECULAR CARCINOGENESIS, 40(1), 62–72.
author keywords: p53 protein; cell cycle; hepatocyte
MeSH headings : Animals; Animals, Newborn; Antibiotics, Antineoplastic / pharmacology; Bleomycin / toxicity; Cell Cycle Proteins / metabolism; Cell Division; Chemokine CXCL1; Chemokines, CXC / metabolism; Cyclin G; Cyclin G1; Cyclin-Dependent Kinase Inhibitor p21; Cyclins / metabolism; DNA / drug effects; DNA / radiation effects; DNA Damage; Disease Models, Animal; Gamma Rays / adverse effects; Insulin-Like Growth Factor Binding Protein 1 / metabolism; Intercellular Signaling Peptides and Proteins / metabolism; Liver / metabolism; Mice; Mice, Inbred C57BL; Nuclear Proteins; Proto-Oncogene Proteins / metabolism; Proto-Oncogene Proteins c-mdm2; Tumor Suppressor Protein p53 / metabolism; Whole-Body Irradiation
TL;DR:
This work characterizes various parameters in the infant mouse, thus validating the use of this model to study in vivo DNA damage–induced cell‐cycle–related changes.
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UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
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