Works (45)

Updated: July 28th, 2023 21:15

2019 journal article

Dietary arachidonate in milk replacer triggers dual benefits of PGE2 signaling in LPS-challenged piglet alveolar macrophages

Journal of Animal Science and Biotechnology, 10(1).

By: K. Walter n, X. Lin n, S. Jacobi*, T. Käser n, D. Esposito n & J. Odle n

Contributors: K. Walter n, X. Lin n, S. Jacobi*, T. Käser n, D. Esposito n & J. Odle n

author keywords: Arachidonic acid; Cyclooxygenase; Eicosanoid; Eicosapentaenoic acid; Inflammation; Lipid mediator class switch; LPS; Lipoxin; Porcine alveolar macrophage
TL;DR: It is inferred that enriching diets with arachidonic acid may be an effective means to enhance a stronger innate immunologic response to respiratory challenges in neonatal pigs, but further work is needed to examine long-term safety, clinical efficacy and economic viability. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, ORCID, Crossref
Added: April 20, 2020

2018 journal article

Effect of In Ovo Zinc Injection on the Embryonic Development and Epigenetics-Related Indices of Zinc-Deprived Broiler Breeder Eggs

Biological Trace Element Research, 185(2), 456–464.

By: X. Sun*, L. Lu*, X. Liao*, L. Zhang*, X. Lin n, X. Luo*, Q. Ma*

author keywords: In ovo zinc injection; Chick embryo; Metallothionein; Epigenetics
MeSH headings : Animals; Antioxidants / metabolism; Chickens; Eggs / analysis; Embryonic Development / drug effects; Epigenesis, Genetic / drug effects; Epigenesis, Genetic / genetics; Female; Random Allocation; Zinc / administration & dosage; Zinc / pharmacology
TL;DR: It is demonstrated that in ovo Zn injection improved the embryonic development, and the organic Zn was more effective than inorganic Zn in enhancing DNA methylation and H3K9 acetylation in the liver MT4 promoter, but the precise mechanisms require further investigations. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, Crossref, NC State University Libraries
Added: October 19, 2018

2017 journal article

Effects of dietary supplementation of resveratrol on performance, egg quality, yolk cholesterol and antioxidant enzyme activity of laying hens

British Poultry Science, 58(5), 544–549.

By: Z. Feng*, J. Gong*, G. Zhao*, X. Lin n, Y. Liu & K. Ma

author keywords: Egg quality; egg yolk cholesterol; laying performance; resveratrol; serum oxidative status
MeSH headings : Animal Feed / analysis; Animals; Antioxidants / metabolism; Chickens / physiology; Cholesterol / metabolism; Diet / veterinary; Dietary Supplements / analysis; Egg Yolk / chemistry; Female; Ovum / physiology; Resveratrol; Stilbenes / administration & dosage; Stilbenes / metabolism
TL;DR: It is concluded that resveratrol supplementation has a positive effect on performance, lipid-related traits and antioxidant activity of laying hens. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, Crossref, NC State University Libraries
Added: August 6, 2018

2017 journal article

Impact of maternal heat stress in conjunction with dietary zinc supplementation on hatchability, embryonic development, and growth performance in offspring broilers

Poultry Science, 96(7), 2351–2359.

By: Y. Zhu*, W. Li*, L. Lu*, L. Zhang*, C. Ji*, X. Lin n, H. Liu n, J. Odle n, X. Luo*

Contributors: Y. Zhu*, W. Li*, L. Lu*, L. Zhang*, C. Ji*, X. Lin n, H. Liu n, J. Odle n, X. Luo*

author keywords: chick embryo; growth performance; maternal heat stress; offspring; zinc
MeSH headings : Animal Feed / analysis; Animal Nutritional Physiological Phenomena / drug effects; Animals; Chick Embryo; Chickens / growth & development; Chickens / physiology; Diet / veterinary; Dietary Supplements / analysis; Embryonic Development / drug effects; Female; Hot Temperature / adverse effects; Male; Random Allocation; Reproduction / drug effects; Zinc / administration & dosage; Zinc / metabolism
TL;DR: It is indicated that maternal heat stress impairs hatching performance, embryonic development, and progeny growth performance, inducing metabolic changes, while supplementation of Zn in maternal diets regardless of ZN sources improved hatch chick quality and survivability of offspring and alleviated the negative effect of maternalHeat stress on growth performance of offspring during the starter period. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, ORCID, Crossref
Added: August 6, 2018

2017 journal article

Manganese enhances the expression of the manganese superoxide dismutase in cultured primary chick embryonic myocardial cells

Journal of Integrative Agriculture, 16(9), 2038–2046.

author keywords: manganese; MnSOD; expressions; cultured primary myocardial cells; chick embryos
TL;DR: The results showed that MnS OD activity and mRNA expression level were induced by Mn and increased with incubation time, which supported the hypothesis that Mn would enhance the expression of the MnSOD gene, and thus might protect myocardial cells from oxidative stress during the chick embryonic development. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, Crossref, NC State University Libraries
Added: August 6, 2018

2017 journal article

Maternal dietary manganese protects chick embryos against maternal heat stress via epigenetic-activated antioxidant and anti-apoptotic abilities

Oncotarget, 8(52), 89665–89680.

By: Y. Zhu*, L. Lu*, X. Liao*, W. Li*, L. Zhang*, C. Ji*, X. Lin n, H. Liu n ...

Contributors: Y. Zhu*, L. Lu*, X. Liao*, W. Li*, L. Zhang*, C. Ji*, X. Lin n, H. Liu n, J. Odle n, X. Luo*

author keywords: epigenetics; maternal environmental hyperthermia; manganese superoxide dismutase; apoptosis; chick embryo
TL;DR: It is suggested that maternal dietary manganese addition could protect the chick embryonic development against maternal heat stress via enhancing epigenetic-activated antioxidant and anti-apoptotic abilities. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Sources: Web Of Science, NC State University Libraries, ORCID, Crossref
Added: August 6, 2018

2017 journal article

Maternal dietary zinc supplementation enhances the epigenetic-activated antioxidant ability of chick embryos from maternal normal and high temperatures

Oncotarget, 8(12), 19814–19824.

By: Y. Zhu*, X. Liao*, L. Lu*, W. Li*, L. Zhang*, C. Ji*, X. Lin n, H. Liu n ...

Contributors: Y. Zhu*, X. Liao*, L. Lu*, W. Li*, L. Zhang*, C. Ji*, X. Lin n, H. Liu n, J. Odle n, X. Luo*

author keywords: epigenetics; maternal hyperthermia; zinc; metallothionein; chick embryo
MeSH headings : Acetylation / drug effects; Animal Nutritional Physiological Phenomena; Animals; Antioxidants / metabolism; Avian Proteins / genetics; Avian Proteins / metabolism; Blotting, Western; Chick Embryo; Chickens; DNA Methylation / drug effects; Dietary Supplements; Epigenesis, Genetic / drug effects; Female; Gene Expression Regulation, Developmental / drug effects; Heat-Shock Proteins / genetics; Heat-Shock Proteins / metabolism; Histones / metabolism; Hot Temperature; Liver / drug effects; Liver / embryology; Liver / metabolism; Lysine / metabolism; Metallothionein / genetics; Metallothionein / metabolism; Reverse Transcriptase Polymerase Chain Reaction; Zinc / administration & dosage; Zinc / pharmacology
TL;DR: It is demonstrated that maternal dietary zinc addition as an epigenetic modifier could protect the offspring embryonic development against maternal heat stress via enhancing the epigenetic-activated antioxidant ability. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, ORCID, Crossref
Added: August 6, 2018

2016 journal article

Asparagine improves intestinal integrity, inhibits TLR4 and NOD signaling, and differently regulates p38 and ERK1/2 signaling in weanling piglets after LPS challenge

Innate Immunity, 22(8), 577–587.

By: S. Chen*, Y. Liu*, X. Wang*, H. Wang*, S. Li*, H. Shi*, H. Zhu*, J. Zhang* ...

Contributors: S. Chen*, Y. Liu*, X. Wang*, H. Wang*, S. Li*, H. Shi*, H. Zhu*, J. Zhang* ...

author keywords: Asparagine; weanling piglets; intestine; lipopolysaccharide; inflammatory response
MeSH headings : Animals; Anti-Inflammatory Agents / pharmacology; Apoptosis / drug effects; Asparagine / pharmacology; Caspase 3 / metabolism; Cell Proliferation / drug effects; Cells, Cultured; Cytokines / metabolism; Enterocytes / drug effects; Enterocytes / physiology; Enzyme Inhibitors / pharmacology; Inflammation / drug therapy; Inflammation Mediators / metabolism; Intestinal Mucosa / immunology; Intestinal Mucosa / pathology; Lipopolysaccharides / immunology; MAP Kinase Signaling System / drug effects; Ornithine Decarboxylase / metabolism; Oxygenases / metabolism; Phosphorylation / drug effects; Swine; Toll-Like Receptor 4 / metabolism; Weaning; p38 Mitogen-Activated Protein Kinases / metabolism
TL;DR: The results suggest that Asn improves intestinal integrity during an inflammatory insult, which appears to be related to the decrease of intestinal pro-inflammatory cytokine and of enterocyte apoptosis (via p38 and ERK1/2). (via Semantic Scholar)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018

2016 journal article

Asparagine reduces the mRNA expression of muscle atrophy markers via regulating protein kinase B (Akt), AMP-activated protein kinase α, toll-like receptor 4 and nucleotide-binding oligomerisation domain protein signalling in weaning piglets after lipopolysaccharide challenge

British Journal of Nutrition, 116(7), 1188–1198.

By: X. Wang*, Y. Liu*, S. Wang*, D. Pi*, W. Leng*, H. Zhu*, J. Zhang*, H. Shi* ...

Contributors: X. Wang*, Y. Liu*, S. Wang*, D. Pi*, W. Leng*, H. Zhu*, J. Zhang*, H. Shi* ...

author keywords: Asparagine; Lipopolysaccharides; Muscle atrophy; Pro-inflammatory cytokines
MeSH headings : AMP-Activated Protein Kinases / antagonists & inhibitors; AMP-Activated Protein Kinases / metabolism; Animals; Asparagine / pharmacology; Enzyme Activation / drug effects; F-Box Proteins / analysis; F-Box Proteins / genetics; Forkhead Box Protein O1 / antagonists & inhibitors; Gene Expression / drug effects; Lipopolysaccharides / pharmacology; Muscle Proteins / metabolism; Muscle, Skeletal / chemistry; Muscular Atrophy / chemically induced; Muscular Atrophy / genetics; Nod Signaling Adaptor Proteins / antagonists & inhibitors; Phosphorylation / drug effects; Polycomb Repressive Complex 1 / analysis; Polycomb Repressive Complex 1 / genetics; Proto-Oncogene Proteins c-akt / metabolism; RNA, Messenger / analysis; Signal Transduction / drug effects; Sus scrofa; Toll-Like Receptor 4 / genetics; Toll-Like Receptor 4 / metabolism; Weaning
TL;DR: The beneficial effects of Asn on muscle atrophy may be associated with inhibiting muscle protein degradation via activating Akt and inactivating AMPKα and FOXO1; and decreasing the expression of muscle pro-inflammatory cytokines via inhibiting TLR4 and NOD signalling pathways by modulation of their negative regulators. (via Semantic Scholar)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018

2016 journal article

Effect of dietary manganese on antioxidant status and expressions of heat shock proteins and factors in tissues of laying broiler breeders under normal and high environmental temperatures

British Journal of Nutrition, 116(11), 1851–1860.

By: Y. Zhu*, L. Lu*, W. Li*, L. Zhang*, C. Ji*, X. Lin n, H. Liu n, J. Odle n, X. Luo*

Contributors: Y. Zhu*, L. Lu*, W. Li*, L. Zhang*, C. Ji*, X. Lin n, H. Liu n, J. Odle n, X. Luo*

author keywords: Broiler breeders; Manganese; Heat stress; Antioxidant status; Heat shock proteins/factors
MeSH headings : Animals; Avian Proteins / genetics; Avian Proteins / metabolism; Biomarkers / metabolism; Chelating Agents / administration & dosage; Chickens / growth & development; Chickens / physiology; China; DNA-Binding Proteins / genetics; DNA-Binding Proteins / metabolism; Diet / veterinary; Female; Gene Expression Regulation, Developmental; HSP70 Heat-Shock Proteins / genetics; HSP70 Heat-Shock Proteins / metabolism; Heart Ventricles / enzymology; Heart Ventricles / growth & development; Heart Ventricles / metabolism; Heat Shock Transcription Factors; Heat-Shock Proteins / genetics; Heat-Shock Proteins / metabolism; Heat-Shock Response; Intestinal Absorption; Liver / enzymology; Liver / growth & development; Liver / metabolism; Manganese / administration & dosage; Manganese / metabolism; Manganese Compounds / administration & dosage; Muscle, Skeletal / enzymology; Muscle, Skeletal / growth & development; Muscle, Skeletal / metabolism; Oxidative Stress; RNA, Messenger / metabolism; Random Allocation; Sulfates / administration & dosage; Trans-Activators / genetics; Trans-Activators / metabolism; Transcription Factors / genetics; Transcription Factors / metabolism
TL;DR: It is indicated that high temperature decreases Mn retention and increases HSP70, HSF1 and HSF3 expressions in the tissues of laying broiler breeders and dietary supplementation with Mn in either source may enhance the heart’s antioxidant ability and inhibit the expression of HSP 70 in breast muscle. (via Semantic Scholar)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018

2016 journal article

Effects of Supplemental Chromium Propionate on Serum Lipids, Carcass Traits, and Meat Quality of Heat-Stressed Broilers

Biological Trace Element Research, 176(2), 401–406.

By: F. Xiao*, D. Ao*, B. Zhou*, J. Spears n, X. Lin n & Y. Huang*

author keywords: Chromium; Heat-stressed broilers; Carcass traits; Serum lipids; Meat quality
MeSH headings : Animals; Chickens; Cholesterol, LDL / blood; Dietary Supplements; Heat Stress Disorders / blood; Heat Stress Disorders / metabolism; Hot Temperature; Male; Meat / analysis; Meat / standards; Propionates / administration & dosage; Propionates / metabolism; Propionates / pharmacology; Triglycerides / blood
TL;DR: It is indicated that CrPro supplementation could be beneficial to serum lipids metabolism of heat-stressed broiler chickens by decreasing TG and LDLC contents, but had no impacts on meat quality and carcass traits of the heat-Stressed broilers. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Sources: Web Of Science, Crossref, NC State University Libraries
Added: August 6, 2018

2015 article

Effect of dietary manganese on antioxidant status and expression levels of heat-shock proteins and factors in tissues of laying broiler breeders under normal and high environmental temperatures (Retracted article. See vol. 119, pg. 117, 2018)

Zhu, Y.-W., Lu, L., Li, W.-X., Zhang, L.-Y., Ji, C., Lin, Xi, … Luo, X.-G. (2015, December 28). BRITISH JOURNAL OF NUTRITION, Vol. 114, pp. 1965–1974.

Contributors: Y. Zhu*, L. Lu*, W. Li*, L. Zhang*, C. Ji*, X. Lin n, H. Liu n, J. Odle n, X. Luo*

author keywords: Broiler breeders; Manganese; Heat stress; Antioxidant status; Heat-shock proteins/factors
MeSH headings : Animals; Antioxidants / metabolism; Chickens; Diet; Female; Heat-Shock Proteins / genetics; Heat-Shock Proteins / metabolism; Hot Temperature; Liver / enzymology; Malondialdehyde / metabolism; Manganese / administration & dosage; Manganese / pharmacokinetics; Myocardium / enzymology; RNA / metabolism; Superoxide Dismutase / metabolism; Temperature; Tissue Distribution
TL;DR: The results indicate that high temperature decreases Mn retention and increases HSP70 and HSF1, HSF3 expression levels in tissues of laying broiler breeders, and dietary supplementation with Mn in either source may enhance heart antioxidant ability and inhibit the expression of HSP 70 in breast muscle. (via Semantic Scholar)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2015 journal article

Effects of Supplemental Chromium Source and Concentration on Growth Performance, Carcass Traits, and Meat Quality of Broilers Under Heat Stress Conditions

Biological Trace Element Research, 170(1), 216–223.

author keywords: Chromium; Growth performance; Carcass characteristics; Meat quality; Broilers; Heat stress
MeSH headings : Animals; Chickens / growth & development; Chromium / administration & dosage; Female; Heat-Shock Response; Poultry
TL;DR: Results from this study indicate that Cr supplementation, independent of its source, could promote growth and improve carcass traits and meat quality of broilers under heat stress conditions. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Sources: Web Of Science, Crossref, NC State University Libraries
Added: August 6, 2018

2015 journal article

Effects of Supplemental Chromium Source and Concentration on Growth, Carcass Characteristics, and Serum Lipid Parameters of Broilers Reared Under Normal Conditions

Biological Trace Element Research, 169(2), 352–358.

author keywords: Broilers; Carcass characteristics; Chromium; Lipid parameters; Normal rearing conditions
MeSH headings : Abdominal Fat / drug effects; Abdominal Fat / growth & development; Animal Feed / analysis; Animals; Chickens / growth & development; Chickens / metabolism; Chlorides / analysis; Chlorides / pharmacology; Cholesterol / blood; Chromium / analysis; Chromium / pharmacology; Chromium Compounds / analysis; Chromium Compounds / pharmacology; Dietary Supplements; Liver / drug effects; Liver / growth & development; Muscle, Skeletal / drug effects; Muscle, Skeletal / growth & development; Picolinic Acids / analysis; Picolinic Acids / pharmacology; Propionates / analysis; Propionates / pharmacology
TL;DR: It is indicated that dietary supplementation of Cr has effects on carcass characteristics and serum lipid parameters of broilers under normal rearing conditions, while supplementation of organic Cr can improve carcasses characteristics and reduce the cholesterol content in serum. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, Crossref, NC State University Libraries
Added: August 6, 2018

2015 journal article

Effects of acute and chronic heat stress on plasma metabolites, hormones and oxidant status in restrictedly fed broiler breeders

Poultry Science, 94(7), 1635–1644.

Contributors: J. Xie*, L. Tang*, L. Lu*, L. Zhang*, X. Lin n, H. Liu n, J. Odle n, X. Luo*

author keywords: broiler breeder; heat stress; metabolite; hormone; oxidation
MeSH headings : Animals; Blood Chemical Analysis / veterinary; Chickens / physiology; Enzyme-Linked Immunosorbent Assay / veterinary; Female; Heat-Shock Response; Hormones / blood; Oxidants / metabolism; Radioimmunoassay / veterinary; Random Allocation
TL;DR: Taking together, acute heat stress primarily resulted in disturbance of plasma metabolites, whereas chronic heat stress caused tissue damage reflected by increased plasma LDA, GOT, and CK. (via Semantic Scholar)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018

2015 journal article

Effects of environmental temperature and dietary manganese on egg production performance, egg quality, and some plasma biochemical traits of broiler breeders

Journal of Animal Science, 93(7), 3431–3440.

By: Y. Zhu*, J. Xie, W. Li*, L. Lu*, L. Zhang*, C. Ji*, X. Lin n, H. Liu n, J. Odle n, X. Luo*

author keywords: broiler breeders; high temperature; laying performance; manganese; plasma biochemical traits
MeSH headings : Animal Feed / analysis; Animal Nutritional Physiological Phenomena; Animals; Chickens / physiology; Diet / veterinary; Dietary Supplements; Eggs / standards; Female; Lipid Peroxidation; Malondialdehyde / metabolism; Manganese / pharmacology; Oviposition / drug effects; Plasma; Protein Carbonylation; Soybeans / chemistry; Temperature
TL;DR: The results from this study indicated that high temperature significantly impaired egg production performance and eggshell quality and induced lipid peroxidation and tissue damage whereas dietary supplementation of either organic or inorganic Mn improved eggshell strength and thermotolerance and reduced protein oxidation and that the organic Mn could alleviate the negative effect of high temperature on eggProduction performance of broiler breeders at the period of 32 to 45 wk of age. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2015 journal article

Effects of maternal dietary manganese and incubation temperature on hatchability, antioxidant status, and expression of heat shock proteins in chick embryos

Journal of Animal Science, 93(12), 5725–5734.

By: Y. Zhu*, L. Lu*, W. Li*, L. Zhang*, C. Ji*, X. Lin n, H. Liu n, J. Odle n, X. Luo*

author keywords: antioxidant status; chick embryo; heat shock protein; incubation temperatures; manganese
MeSH headings : Animal Feed / analysis; Animal Feed / standards; Animals; Antioxidants / metabolism; Body Weight; Chick Embryo / metabolism; Chick Embryo / physiology; Chickens / physiology; Diet / veterinary; Dietary Supplements; Egg Yolk / chemistry; Female; Heat-Shock Proteins / metabolism; Hot Temperature / adverse effects; Liver / embryology; Liver / enzymology; Liver / metabolism; Malondialdehyde / analysis; Manganese / administration & dosage; Manganese / analysis; Manganese / pharmacology; Maternal Nutritional Physiological Phenomena / physiology; Myocardium / enzymology; Random Allocation; Superoxide Dismutase / analysis; Superoxide Dismutase / genetics
TL;DR: Maternal dietary supplementation of Mn could improve the hatchability as well as antioxidant ability to protect against heat challenge in embryos during incubation, and indicated that high incubation temperature induced self-protective responses of chick embryos with a modification of antioxidant status and a depression of HSP70 protein level. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2015 journal article

Effects of pre-slaughter stressor and feeding preventative Chinese medicinal herbs on glycolysis and oxidative stability in pigs

Animal Science Journal, 87(8), 1028–1033.

By: X. Bai, X. Yan, L. Xie, X. Hu, X. Lin n, C. Wu, N. Zhou*, A. Wang, M. See n

Contributors: X. Bai, X. Yan, L. Xie, X. Hu, X. Lin n, C. Wu, N. Zhou*, A. Wang, M. See n

author keywords: Chinese medicinal herbs; glycogen; oxidative; pig; stress
MeSH headings : Abattoirs; Animal Feed; Animals; Antioxidants; Blood Glucose / metabolism; Diet / veterinary; Dietary Supplements; Female; Glycolysis / drug effects; Lactic Acid / blood; Lycium; Male; Oxidation-Reduction / drug effects; Oxidative Stress / physiology; Plants, Medicinal; Polygala; Soybeans; Stress, Physiological / physiology; Swine / metabolism; Swine / physiology; Zea mays
TL;DR: It is shown that pre-slaughter stress induces oxidative stress in pigs and dietary supplementation with 1% LB improves antioxidant capacity in stressed pigs before slaughtering. (via Semantic Scholar)
UN Sustainable Development Goal Categories
13. Climate Action (Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018

2015 journal article

Transplacental induction of fatty acid oxidation in term fetal pigs by the peroxisome proliferator-activated receptor alpha agonist clofibrate

Journal of Animal Science and Biotechnology, 6(1).

By: X. Lin n, S. Jacobi n & J. Odle n

Contributors: X. Lin n, S. Jacobi n & J. Odle n

author keywords: Clofibrate; Fatty acid oxidation; Pigs; Placenta transfer
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018

2014 journal article

Clofibrate Increases Long-Chain Fatty Acid Oxidation by Neonatal Pigs

The Journal of Nutrition, 144(11), 1688–1693.

By: X. Bai n, X. Lin n, J. Drayton n, Y. Liu n, C. Ji* & J. Odle n

Contributors: X. Bai n, X. Lin n, J. Drayton n, Y. Liu n, C. Ji* & J. Odle n

MeSH headings : Animals; Animals, Newborn; Anticholesteremic Agents / pharmacology; Clofibrate / pharmacology; Fatty Acids / metabolism; Liver / drug effects; Liver / metabolism; Male; Oxidation-Reduction / drug effects; RNA, Messenger / genetics; RNA, Messenger / metabolism; Weight Gain
TL;DR: Clofibrate may improve in vivo LCFA oxidative utilization in neonatal pigs to increase efficiency of milk fat utilization by newborn pigs. (via Semantic Scholar)
Sources: Web Of Science, ORCID, Crossref, NC State University Libraries
Added: August 6, 2018

2014 journal article

Dietary supplementation of aspartate enhances intestinal integrity and energy status in weanling piglets after lipopolysaccharide challenge

The Journal of Nutritional Biochemistry, 25(4), 456–462.

By: D. Pi*, Y. Liu*, H. Shi*, S. Li*, J. Odle n, X. Lin n, H. Zhu*, F. Chen* ...

Contributors: D. Pi*, Y. Liu*, H. Shi*, S. Li*, J. Odle n, X. Lin n, H. Zhu*, F. Chen*, Y. Hou*, W. Leng*

author keywords: Aspartate; Intestine; Energy status; Weanling piglets; Lipopolysaccharide
MeSH headings : AMP-Activated Protein Kinases / genetics; AMP-Activated Protein Kinases / metabolism; Adenosine Diphosphate / metabolism; Adenosine Monophosphate / metabolism; Adenosine Triphosphate / metabolism; Animals; Aspartic Acid / pharmacology; Body Weight / drug effects; DNA / metabolism; Dietary Supplements; Histone Deacetylases / genetics; Intestinal Mucosa / drug effects; Intestinal Mucosa / metabolism; Intestines / drug effects; Lactase / metabolism; Lipopolysaccharides / toxicity; Phosphorylation / drug effects; Proteins / metabolism; Sucrase / metabolism; Swine; Transcription Factors / genetics; Weaning
TL;DR: Results indicate that Asp may alleviate LPS-induced intestinal damage and improve intestinal energy status. (via Semantic Scholar)
UN Sustainable Development Goal Categories
7. Affordable and Clean Energy (OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018

2014 journal article

Effects of Supplemental Copper on the Serum Lipid Profile, Meat Quality, and Carcass Composition of Goat Kids

Biological Trace Element Research, 159(1-3), 140–146.

author keywords: Carcass composition; Copper; Goat; Meat quality; Serum lipid profile
MeSH headings : Animal Feed; Animals; Body Composition / drug effects; Copper / pharmacology; Dietary Supplements; Goats; Lipid Metabolism / drug effects; Male; Meat / analysis
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Sources: Web Of Science, Crossref, NC State University Libraries
Added: August 6, 2018

2014 journal article

The Suckling Piglet as an Agrimedical Model for the Study of Pediatric Nutrition and Metabolism

Annual Review of Animal Biosciences, 2(1), 419–444.

By: J. Odle n, X. Lin n, S. Jacobi n, S. Kim n & C. Stahl n

Contributors: J. Odle n, X. Lin n, S. Jacobi n, S. Kim n & C. Stahl n

author keywords: agrimedical; milk; infant; fatty acid; oligosaccharide; amino acid; calcium; phosphorous
MeSH headings : Animal Nutritional Physiological Phenomena; Animals; Animals, Suckling; Child; Child Nutritional Physiological Phenomena; Humans; Swine / physiology
TL;DR: The broad scope of this review is to outline the fundamental elements of the piglet model and to highlight key aspects of relevance to various macronutrients, including lipids, carbohydrates, proteins/amino acids, and calcium/phosphorus. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018

2013 journal article

Diet physical form, fatty acid chain length, and emulsification alter fat utilization and growth of newly weaned pigs

Journal of Animal Science, 91(2), 783–792.

By: K. Price n, X. Lin n, E. van Heugten n, R. Odle n, G. Willis & J. Odle n

Contributors: K. Price n, X. Lin n, E. Van Heugten n, R. Odle n, G. Willis & J. Odle n

author keywords: emulsification; fat digestibility; medium chain triglyceride; milk replacer; pigs
MeSH headings : Animal Feed / analysis; Animals; Bile Acids and Salts / physiology; Diet / veterinary; Dietary Fats / metabolism; Digestion / physiology; Fatty Acids / chemistry; Female; Jejunum / physiology; Ketone Bodies / blood; Male; Swine / growth & development; Swine / physiology; Weaning
TL;DR: It is concluded that feeding liquid diets containing emulsified LCT can improve fat utilization and markedly accentuate feed intake, growth, and G:F of weanling pigs. (via Semantic Scholar)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018

2013 journal article

Dietary supplementation of Bifidobacterium longum strain AH1206 increases its cecal abundance and elevates intestinal interleukin-10 expression in the neonatal piglet

Food and Chemical Toxicology, 60, 116–122.

By: T. Herfel n, S. Jacobi n, X. Lin n, Z. Jouni*, M. Chichlowski*, C. Stahl n, J. Odle n

Contributors: T. Herfel n, S. Jacobi n, X. Lin n, Z. Jouni*, M. Chichlowski*, C. Stahl n, J. Odle n

author keywords: Bifidobacteria; Probiotic; Infant; Intestinal health; Immune system; IL-10
MeSH headings : Animal Feed / microbiology; Animals; Animals, Newborn; Bifidobacterium; Cecum / microbiology; Colony Count, Microbial; Dietary Supplements; Immunoglobulin G / blood; Immunoglobulin M / blood; Interleukin-10 / genetics; Interleukin-10 / metabolism; Probiotics / administration & dosage; Swine; Weight Gain
TL;DR: Dietary supplementation with B. longum (AH1206) may be safe for human infants based on a lack of growth, development or deleterious immune-related effects observed in piglets, based on findings in the suckling piglet model. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018

2013 journal article

Early postnatal kinetics of colostral immunoglobulin G absorption in fed and fasted piglets and developmental expression of the intestinal immunoglobulin G receptor

Journal of Animal Science, 91(1), 211–218.

By: R. Cabrera n, X. Lin n, M. Ashwell n, A. Moeser n & J. Odle n

Contributors: R. Cabrera n, X. Lin n, M. Ashwell n, A. Moeser n & J. Odle n

author keywords: colostral immunoglobulin G; immunoglobulin G receptor; serum immunoglobulin G
MeSH headings : Absorption; Animals; Animals, Newborn; Colostrum / chemistry; Food Deprivation; Gene Expression Regulation, Developmental / drug effects; Immunoglobulin G / administration & dosage; Immunoglobulin G / chemistry; Intestinal Mucosa / metabolism; Intestines / drug effects; Receptors, IgG / genetics; Receptors, IgG / metabolism; Swine / metabolism
TL;DR: The effects of delayed offering of defatted colostrum and age-dependent changes in IgG receptor were modest over the first 24 h of life. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Sources: Web Of Science, NC State University Libraries, ORCID, Crossref
Added: August 6, 2018

2013 journal article

Effect of copper on performance, carcass characteristics, and muscle fatty acid composition of meat goat kids

Journal of Animal Science, 91(10), 5004–5010.

By: Y. Huang*, Y. Wang*, J. Spears n, X. Lin n & C. Guo*

author keywords: carcass characteristics; copper; fatty acid composition; meat goat kids; performance
MeSH headings : Animal Feed / analysis; Animal Nutritional Physiological Phenomena; Animals; Body Composition / drug effects; Copper / pharmacology; Diet / veterinary; Fatty Acids / genetics; Fatty Acids / metabolism; Goats / growth & development; Goats / physiology; Male; Muscle, Skeletal / chemistry; Muscle, Skeletal / metabolism; Reference Values
TL;DR: The results indicate that JYB goats can tolerate up to 640 mg Cu/kg DM for 96 d without adverse effects on performance, but fat deposition and fatty acid composition in the body could be altered by Cu supplementation as low as 20 mg/kg of diet with high concentrate-hay. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, Crossref, NC State University Libraries
Added: August 6, 2018

2013 journal article

Effect of dietary selenium on boar sperm quality

Animal Reproduction Science, 138(3-4), 268–275.

By: K. Lovercamp n, K. Stewart n, X. Lin n & W. Flowers n

author keywords: Boar; Selenium; Sperm; Lipid peroxidation; Glutathione peroxidise
MeSH headings : Animal Feed; Animal Nutritional Physiological Phenomena / drug effects; Animals; Cell Shape / drug effects; Dietary Supplements; Fatty Acids / analysis; Fatty Acids / metabolism; Glutathione Peroxidase / analysis; Glutathione Peroxidase / metabolism; Lipid Peroxidation / drug effects; Male; Selenium / administration & dosage; Selenium / analysis; Semen / chemistry; Semen / cytology; Semen / drug effects; Semen / metabolism; Semen Analysis / veterinary; Semen Preservation / veterinary; Swine / metabolism; Swine / physiology
TL;DR: Results indicate that supplementing a basal diet with organic or inorganic selenium did not affect semen quantity or sperm quality in fresh ejaculates nor did it appear to have any beneficial latent effects in extended semen stored post collection. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, Crossref, NC State University Libraries
Added: August 6, 2018

2013 journal article

Fish Oil Alleviates Activation of the Hypothalamic-Pituitary-Adrenal Axis Associated with Inhibition of TLR4 and NOD Signaling Pathways in Weaned Piglets after a Lipopolysaccharide Challenge

The Journal of Nutrition, 143(11), 1799–1807.

By: Y. Liu*, F. Chen*, Q. Li*, J. Odle n, X. Lin n, H. Zhu*, D. Pi*, Y. Hou* ...

Contributors: Y. Liu*, F. Chen*, Q. Li*, J. Odle n, X. Lin n, H. Zhu*, D. Pi*, Y. Hou*, Y. Hong*, H. Shi*

MeSH headings : Adrenal Glands / drug effects; Adrenal Glands / metabolism; Adrenocorticotropic Hormone / blood; Animals; Corticotropin-Releasing Hormone / blood; Cyclooxygenase 2 / genetics; Cyclooxygenase 2 / metabolism; Disease Models, Animal; Docosahexaenoic Acids / pharmacology; Down-Regulation; Eicosapentaenoic Acid / pharmacology; Fish Oils / pharmacology; Hypothalamo-Hypophyseal System / drug effects; Hypothalamo-Hypophyseal System / metabolism; Hypothalamus / drug effects; Hypothalamus / metabolism; Interleukin-1 Receptor-Associated Kinases / genetics; Interleukin-1 Receptor-Associated Kinases / metabolism; Lipopolysaccharides / toxicity; Myeloid Differentiation Factor 88 / genetics; Myeloid Differentiation Factor 88 / metabolism; Nod Signaling Adaptor Proteins / antagonists & inhibitors; Nod Signaling Adaptor Proteins / genetics; Nod Signaling Adaptor Proteins / metabolism; Pituitary Gland / drug effects; Pituitary Gland / metabolism; Pituitary-Adrenal System / drug effects; Pituitary-Adrenal System / metabolism; Pro-Opiomelanocortin / blood; RNA, Messenger / genetics; RNA, Messenger / metabolism; Spleen / drug effects; Spleen / metabolism; Swine; Thymus Gland / drug effects; Thymus Gland / metabolism; Toll-Like Receptor 4 / antagonists & inhibitors; Toll-Like Receptor 4 / genetics; Toll-Like Receptor 4 / metabolism; Tumor Necrosis Factor-alpha / genetics; Tumor Necrosis Factor-alpha / metabolism; Weaning
TL;DR: Dietary treatment with fish oil could mitigate LPS-induced activation of the hypothalamic-pituitary-adrenal (HPA) axis through inhibition of Toll-like receptor 4 and nucleotide-binding oligomerization domain protein signaling pathways, and the beneficial effects of FO on the HPA axis may be associated with decreasing the production of brain or peripheral proinflammatory cytokines through inhibition. (via Semantic Scholar)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018

2013 journal article

Fish Oil Increases Muscle Protein Mass and Modulates Akt/FOXO, TLR4, and NOD Signaling in Weanling Piglets After Lipopolysaccharide Challenge

The Journal of Nutrition, 143(8), 1331–1339.

MeSH headings : Animals; Cyclooxygenase 2 / genetics; Cyclooxygenase 2 / metabolism; Docosahexaenoic Acids / administration & dosage; Eicosapentaenoic Acid / administration & dosage; Fish Oils / administration & dosage; Forkhead Transcription Factors / genetics; Forkhead Transcription Factors / metabolism; Lipopolysaccharides / adverse effects; Muscle Proteins / metabolism; Muscle, Skeletal / drug effects; Muscle, Skeletal / metabolism; Myeloid Differentiation Factor 88 / genetics; Myeloid Differentiation Factor 88 / metabolism; NF-kappa B / genetics; NF-kappa B / metabolism; Nod1 Signaling Adaptor Protein / genetics; Nod1 Signaling Adaptor Protein / metabolism; Proto-Oncogene Proteins c-akt / genetics; Proto-Oncogene Proteins c-akt / metabolism; Signal Transduction / drug effects; Swine; Toll-Like Receptor 4 / genetics; Toll-Like Receptor 4 / metabolism; Tumor Necrosis Factor-alpha / genetics; Tumor Necrosis Factor-alpha / metabolism
TL;DR: Results indicate fish oil may suppress muscle proinflammatory cytokine production via regulation of TLR and NOD signaling pathways and therefore improve muscle protein mass, possibly through maintenance of Akt/FOXO signaling. (via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018

2013 journal article

Stabilized rice bran improves weaning pig performance via a prebiotic mechanism

Journal of Animal Science, 91(2), 907–913.

By: T. Herfel n, S. Jacobi n, X. Lin n, E. Van Heugten n, V. Fellner n & J. Odle n

Contributors: T. Herfel n, S. Jacobi n, X. Lin n, E. Heugten n, V. Fellner n & J. Odle n

author keywords: antibiotics; gastrointestinal; microbiota; stabilized rice bran; swine
MeSH headings : Animal Feed / analysis; Animal Nutritional Physiological Phenomena; Animals; Diet / veterinary; Intestines / anatomy & histology; Oryza / chemistry; Prebiotics; Swine / growth & development
TL;DR: SRB improved the efficiency of nutrient utilization in nursery diets lacking antibiotics and tended to increase intestinal bifidobacteria concentrations, indicating that SRB may exert beneficial prebiotic effects in weanling pigs. (via Semantic Scholar)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018

2012 journal article

Fish Oil Enhances Intestinal Integrity and Inhibits TLR4 and NOD2 Signaling Pathways in Weaned Pigs after LPS Challenge

The Journal of Nutrition, 142(11), 2017–2024.

Contributors: Y. Liu*, F. Chen*, J. Odle n, X. Lin n, S. Jacobi n, H. Zhu*, Z. Wu*, Y. Hou*

MeSH headings : Animal Feed / analysis; Animals; Diet / veterinary; Docosahexaenoic Acids / chemistry; Docosahexaenoic Acids / metabolism; Eicosapentaenoic Acid / chemistry; Eicosapentaenoic Acid / metabolism; Fatty Acids, Omega-3 / genetics; Fatty Acids, Omega-3 / metabolism; Fish Oils / pharmacology; Gene Expression Regulation / drug effects; Intestinal Diseases / chemically induced; Intestinal Diseases / metabolism; Intestinal Mucosa; Intestines / drug effects; Lipopolysaccharides / toxicity; Nod2 Signaling Adaptor Protein / genetics; Nod2 Signaling Adaptor Protein / metabolism; RNA, Messenger / genetics; RNA, Messenger / metabolism; Real-Time Polymerase Chain Reaction; Swine / metabolism; Toll-Like Receptor 4 / genetics; Toll-Like Receptor 4 / metabolism
TL;DR: Results indicate that fish oil supplementation is associated with inhibition of TLR4 and NOD2 signaling pathways and concomitant improvement of intestinal integrity under an inflammatory condition. (via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018

2011 journal article

Dietary Arachidonate Differentially Alters Desaturase-Elongase Pathway Flux and Gene Expression in Liver and Intestine of Suckling Pigs

The Journal of Nutrition, 141(4), 548–553.

By: S. Jacobi n, X. Lin n, B. Corl n, H. Hess n, R. Harrell n & J. Odle n

Contributors: S. Jacobi n, X. Lin n, B. Corl n, H. Hess n, R. Harrell n & J. Odle n

MeSH headings : Acetyltransferases / genetics; Acetyltransferases / metabolism; Animals; Animals, Suckling; Arachidonic Acid / administration & dosage; Delta-5 Fatty Acid Desaturase; Fatty Acid Desaturases / genetics; Fatty Acid Desaturases / metabolism; Fatty Acid Elongases; Fatty Acids / metabolism; Intestinal Mucosa / metabolism; Linoleoyl-CoA Desaturase / genetics; Linoleoyl-CoA Desaturase / metabolism; Liver / metabolism; Organ Specificity; Protein Transport; RNA, Messenger / analysis; Swine
TL;DR: D dietary ARA regulated the desaturase-elongase pathway in a tissue-specific manner in liver and intestine, and had modest effects on (n-6) fatty acid flux, and intestinal FADS2 activity and mRNA increased. (via Semantic Scholar)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018

2011 journal article

Dietary conjugated linoleic acid alters long chain polyunsaturated fatty acid metabolism in brain and liver of neonatal pigs

The Journal of Nutritional Biochemistry, 22(11), 1047–1054.

By: X. Lin n, J. Bo n, S. Oliver n, B. Corl n, S. Jacobi n, W. Oliver n, R. Harrell n, J. Odle n

Contributors: X. Lin n, J. Bo n, S. Oliver n, B. Corl n, S. Jacobi n, W. Oliver n, R. Harrell n, J. Odle n

MeSH headings : Acetyltransferases / metabolism; Animals; Animals, Newborn; Arachidonic Acid / metabolism; Brain / metabolism; Dietary Fats / administration & dosage; Fatty Acid Desaturases / metabolism; Fatty Acid Elongases; Fatty Acids, Unsaturated / metabolism; Linoleic Acid / metabolism; Linoleic Acids, Conjugated / pharmacology; Liver / metabolism; Swine
TL;DR: Overall, the data show that dietary CLA shifted the distribution of the synthetic products of [U-(13)C]LA between elongation and desaturation in liver and decreased the total synthetic products in brain by inhibiting LA elongation to C20:2n-6. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: NC State University Libraries, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018

2011 journal article

Evaluation of the nutritional value of glycerol for nursery pigs

Journal of Animal Science, 89(7), 2145–2153.

By: M. Shields n, E. van Heugten n, X. Lin n, J. Odle n & C. Stark n

Contributors: M. Shields n, E. Heugten n, X. Lin n, J. Odle n & C. Stark n

author keywords: glycerol; lactose; nursery; pig
MeSH headings : Animal Feed / analysis; Animal Nutritional Physiological Phenomena; Animals; Diet / veterinary; Female; Glycerol / administration & dosage; Glycerol / pharmacology; Lactose; Lethal Dose 50; Male; Swine / growth & development; Weight Gain; Zea mays
TL;DR: Overall, data indicate that glycerol can be added to nursery pig diets at 10%, while improving growth performance, and there was no effect of feeding Glycerol during the starter 1 phase on subsequent performance during thestarter 2 phase or overall. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018

2011 journal article

Polydextrose Enrichment of Infant Formula Demonstrates Prebiotic Characteristics by Altering Intestinal Microbiota, Organic Acid Concentrations, and Cytokine Expression in Suckling Piglets

The Journal of Nutrition, 141(12), 2139–2145.

By: T. Herfel n, S. Jacobi n, X. Lin n, V. Fellner n, D. Walker*, Z. Jouni*, J. Odle n

Contributors: T. Herfel n, S. Jacobi n, X. Lin n, V. Fellner n, D. Walker*, Z. Jouni*, J. Odle n

MeSH headings : Animals; Animals, Newborn / growth & development; Bifidobacterium / drug effects; Bifidobacterium / growth & development; Cytokines / drug effects; Cytokines / genetics; Cytokines / metabolism; Food, Fortified; Glucans / administration & dosage; Glucans / analysis; Humans; Infant; Infant Food; Infant Formula / chemistry; Intestines / microbiology; Lactic Acid / analysis; Lactobacillus / drug effects; Lactobacillus / growth & development; Metagenome; Milk, Human / chemistry; Models, Animal; Oligosaccharides / administration & dosage; Oligosaccharides / analysis; Prebiotics; Propionates / analysis; RNA / isolation & purification; RNA, Messenger; Real-Time Polymerase Chain Reaction; Swine
TL;DR: PDX enrichment of infant formula resulted in a prebiotic effect by increasing ileal lactobacilli and propionic and lactic acid concentrations and decreasing pH with associated alterations in ileale cytokine expression. (via Semantic Scholar)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018

2010 journal article

Carnitine palmitoyltransferase I control of acetogenesis, the major pathway of fatty acid β-oxidation in liver of neonatal swine

American Journal of Physiology-Regulatory, Integrative and Comparative Physiology, 298(5), R1435–R1443.

By: X. Lin n, K. Shim n & J. Odle n

Contributors: X. Lin n, K. Shim n & J. Odle n

author keywords: acetate; anaplerosis; carnitine palmitoyltransferase I activity; ketone bodies; mitochondria; Sus scrofa
MeSH headings : Acetates / metabolism; Acetyl-CoA Hydrolase / metabolism; Age Factors; Animals; Animals, Suckling; Carbon Radioisotopes; Carnitine O-Palmitoyltransferase / genetics; Carnitine O-Palmitoyltransferase / metabolism; Citric Acid / metabolism; Citric Acid Cycle / physiology; Enzyme Activation / physiology; Fatty Acids / metabolism; Gene Expression Regulation, Enzymologic; Ketone Bodies / metabolism; Liver / enzymology; Malonyl Coenzyme A / metabolism; Mitochondria / metabolism; Mitochondria, Liver / enzymology; Oxidation-Reduction; Palmitates / pharmacokinetics; Palmitoyl Coenzyme A / metabolism; RNA, Messenger / metabolism; Sus scrofa / metabolism
TL;DR: It is demonstrated that acetate is the primary product of hepatic mitochondrial beta-oxidation in Sus scrofa and that regulation during early development is mediated primarily via kinetic modulation of CPT I. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018

2009 journal article

Safety evaluation of polydextrose in infant formula using a suckling piglet model

Food and Chemical Toxicology, 47(7), 1530–1537.

By: T. Herfel n, S. Jacobi n, X. Lin n, D. Walker*, Z. Jouni* & J. Odle n

Contributors: T. Herfel n, S. Jacobi n, X. Lin n, D. Walker*, Z. Jouni* & J. Odle n

author keywords: Polydextrose; Prebiotic; Infant; Oligosaccharide; Soluble fiber
MeSH headings : Amylases / analysis; Amylases / metabolism; Animals; Animals, Suckling; Blood Cell Count; Blood Chemical Analysis; Body Weight / drug effects; DNA / biosynthesis; Diet; Feces / chemistry; Food Additives / toxicity; Glucans / toxicity; Health Status; Humans; Infant; Infant Food / toxicity; Organ Size / drug effects; Pancreas / drug effects; Pancreas / metabolism; Swine
TL;DR: Polydextrose mimicked other prebiotic carbohydrates and had no adverse effect at the highest tested level 17.0 g PDX/L, equivalent to a dose of 8.35 g/kg of body weight per day. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018

2008 journal article

Effects of feeding l-carnitine to gilts through day 70 of gestation on litter traits and the expression of insulin-like growth factor system components and l-carnitine concentration in foetal tissues

Journal of Animal Physiology and Animal Nutrition, 92(6), 660–667.

By: K. Brown*, R. Goodband*, M. Tokach*, S. Dritz*, J. Nelssen*, J. Minton*, J. Higgins*, X. Lin n ...

Contributors: K. Brown*, R. Goodband*, M. Tokach*, S. Dritz*, J. Nelssen*, J. Minton*, J. Higgins*, X. Lin n ...

author keywords: foetus; gestation; gilts; l-carnitine; messenger RNA
MeSH headings : Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Carnitine / administration & dosage; Dietary Supplements; Female; Fetal Development / drug effects; Fetal Development / physiology; Gestational Age; Insulin-Like Growth Factor I / metabolism; Liver / metabolism; Muscle, Skeletal / metabolism; Pregnancy; Pregnancy, Animal / blood; Pregnancy, Animal / metabolism; RNA, Messenger / metabolism; Random Allocation; Somatomedins / metabolism; Swine / blood; Swine / growth & development; Swine / metabolism; Swine / physiology
TL;DR: It was shown that L-carnitine had beneficial effects on the average foetal weight at day 70 of gestation, associated with changes in thefoetal IGF system. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018

2008 journal article

Enrichment of Intestinal Mucosal Phospholipids with Arachidonic and Eicosapentaenoic Acids Fed to Suckling Piglets Is Dose and Time Dependent

The Journal of Nutrition, 138(11), 2164–2171.

By: H. Hess n, B. Corl n, X. Lin n, S. Jacobi n, R. Harrell n, A. Blikslager n, J. Odle n

Contributors: H. Hess n, B. Corl n, X. Lin n, S. Jacobi n, R. Harrell n, A. Blikslager n, J. Odle n

MeSH headings : Animals; Arachidonic Acid / administration & dosage; Arachidonic Acid / pharmacology; Diet; Dose-Response Relationship, Drug; Drug Administration Schedule; Eicosapentaenoic Acid / administration & dosage; Eicosapentaenoic Acid / pharmacology; Intestinal Mucosa / drug effects; Intestinal Mucosa / metabolism; Lactase / metabolism; Swine
TL;DR: D doses demonstrate a dose-dependent response of intestinal mucosal phospholipid ARA concentration to dietary ARA with nearly full enrichment attained within 8 d of feeding formula containing ARA and that supra-physiologic supplementation of ARA is not detrimental to growth. (via Semantic Scholar)
Sources: Web Of Science, Crossref, ORCID, NC State University Libraries
Added: August 6, 2018

2007 journal article

Ontogeny of Carnitine Palmitoyltransferase I Activity, Carnitine-Km, and mRNA Abundance in Pigs throughout Growth and Development

The Journal of Nutrition, 137(4), 898–903.

By: P. Lyvers Peffer n, X. Lin n, S. Jacobi n, L. Gatlin n, J. Woodworth* & J. Odle n

Contributors: P. Peffer n, X. Lin n, S. Jacobi n, L. Gatlin n, J. Woodworth* & J. Odle n

MeSH headings : Aging / metabolism; Animal Feed; Animals; Animals, Newborn; Animals, Suckling / metabolism; Carnitine / metabolism; Carnitine O-Palmitoyltransferase / genetics; Carnitine O-Palmitoyltransferase / metabolism; Female; Gene Expression; Kinetics; Lipid Metabolism / physiology; Liver / metabolism; Male; Muscle, Skeletal / metabolism; Osmolar Concentration; RNA, Messenger / metabolism; Swine / growth & development; Swine / metabolism
TL;DR: It is suggested that postnatal increases in CPT I activity during the suckling period are accompanied by increased tissue carnitine, and the lack of hepatic C PT I mRNA induction and low activity reported in both tissues prior to 1 wk of age may limit postnatal lipid utilization during the piglet's transition to extra-uterine life. (via Semantic Scholar)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018

2006 journal article

Ontogeny and chain-length specificity of gastrointestinal lipases affect medium-chain triacylglycerol utilization by newborn pigs

Journal of Animal Science, 84(4), 818–825.

By: M. Dicklin*, J. Robinson*, X. Lin n & J. Odle n

author keywords: fat digestion; lipase; medium-chain triacylglycerol; ontogeny; pig
MeSH headings : Animals; Animals, Newborn / metabolism; Colostrum; Lipase / metabolism; Pancreas / enzymology; Swine / growth & development; Swine / metabolism; Triglycerides / metabolism
TL;DR: Pancreatic lipase dominates the preduodenal lipases in the neonatal pig, and greater activity of the gastrointestinal lipases toward tri-C6:0 underlies its increased rate of use. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2005 journal article

Hepatic β-oxidation and carnitine palmitoyltransferase I in neonatal pigs after dietary treatments of clofibric acid, isoproterenol, and medium-chain triglycerides

American Journal of Physiology-Regulatory, Integrative and Comparative Physiology, 288(6), R1518–R1524.

By: P. Peffer n, X. Lin n & J. Odle n

Contributors: P. Peffer n, X. Lin n & J. Odle n

author keywords: acyl-CoA oxidase; fatty acid oxidase; malonyl-CoA; peroxisome; peroxisome proliferator; activated receptor
MeSH headings : Adrenergic beta-Agonists / pharmacology; Animals; Animals, Newborn / metabolism; Carnitine O-Palmitoyltransferase / metabolism; Clofibric Acid / pharmacology; DNA Primers; DNA, Complementary / biosynthesis; DNA, Complementary / genetics; Diet; Glucose / metabolism; Hypolipidemic Agents / pharmacology; Indicators and Reagents; Isoproterenol / pharmacology; Liver / metabolism; Mitochondria, Liver / enzymology; Mitochondria, Liver / metabolism; Oxidation-Reduction; Palmitic Acids / metabolism; Peroxisomes / metabolism; RNA, Messenger / biosynthesis; RNA, Messenger / genetics; Reverse Transcriptase Polymerase Chain Reaction; Swine; Triglycerides / pharmacology
TL;DR: A suckling piglet model was used to study nutritional and pharmacologic means of stimulating hepatic fatty acid β-oxidation and its applications in nutrition and medicine. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018

2005 journal article

Ontogeny and kinetics of carnitine palmitoyltransferase in liver and skeletal muscle of the domestic felid ()

The Journal of Nutritional Biochemistry, 16(6), 331–338.

By: X. Lin n, R. House n & J. Odle n

Contributors: X. Lin n, R. House n & J. Odle n

author keywords: fatty acid oxidation; feline development; lipid metabolism; cats; CPT
MeSH headings : Animals; Carnitine / analogs & derivatives; Carnitine / metabolism; Carnitine O-Palmitoyltransferase / biosynthesis; Carnitine O-Palmitoyltransferase / metabolism; Cats / growth & development; Cats / metabolism; Kinetics; Liver / enzymology; Liver / growth & development; Muscle, Skeletal / enzymology; Muscle, Skeletal / growth & development
TL;DR: It is concluded that postnatal increases in CPT activity support increased capacity for fatty acid oxidation in the developing felid and that dietary carnitine may be required to maximize enzyme activity. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018

2004 journal article

Refining in vitro digestibility assays: Fractionation of digestible and indigestible peptides

Journal of Animal Science, 82(6), 1669–1677.

MeSH headings : Amino Acids / metabolism; Animal Feed; Animals; Chromatography, Gel / veterinary; Dietary Proteins / metabolism; Digestion; Homoarginine / metabolism; Ileum / metabolism; In Vitro Techniques; Male; Particle Size; Random Allocation; Solubility; Swine / metabolism
TL;DR: In vitro digestibility assays should exhaustively digest proteins to mimic in vivo digestibility, and an in vitro assay based on these principles lacked precision for highly water-soluble AA, and underestimated digestibility for other AA. (via Semantic Scholar)
Sources: NC State University Libraries, Crossref, NC State University Libraries
Added: August 6, 2018

Citation Index includes data from a number of different sources. If you have questions about the sources of data in the Citation Index or need a set of data which is free to re-distribute, please contact us.

Certain data included herein are derived from the Web of Science© and InCites© (2024) of Clarivate Analytics. All rights reserved. You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.