@article{ma_cao_liang_li_lucia_wang_2018, title={Active Tara Gum/PVA Blend Films with Curcumin-Loaded CTAC Brush-TEMPO-Oxidized Cellulose Nanocrystals}, volume={6}, ISSN={["2168-0485"]}, DOI={10.1021/acssuschemeng.8b01281}, abstractNote={Active films containing curcumin exhibit outstanding antioxidant and antibacterial properties. Because of curcumin’s poor solubility in water, cetyltrimethylammonium chloride (CTAC) brush-TEMPO-oxidized cellulose nanocrystal (TCN) colloidal systems were prepared to be used as a delivery excipient to modulate the hosting of curcumin. The curcumin-loaded cellulose nanocrystals were incorporated in a tara gum/PVA blend film to prepare antioxidant and antibacterial films. Fourier transform infrared (FTIR) spectroscopy, X-ray diffraction (XRD) measurements, transmission electron microscope (TEM), and solid-state 13C NMR spectroscopy were performed to characterize the products. The results indicate the synthesis of TCN with a carboxyl content of 1.1878 mmol/g and 0.71 degree of substitution of CTAC based on carboxyl groups. There was 26.57% of the curcumin bound in the brush. The mechanical properties and barrier properties of the films were characterized. DPPH and ABTS+ assays were used to measure the antioxidant properties. The activities against Gram-negative (E. coli) and Gram-positive (S. aureus) bacteria were also evaluated. The release of curcumin from the films into food simulants were also characterized to determine whether the antioxidants could provide intermediate protection from lipid oxidation. The results show that the mechanical and barrier properties of the films improved although water the vapor permeability slightly decreased. The film possessed desirable antioxidant and antibacterial properties. The release test revealed that curcumin was initially released rapidly into 50% ethanol solution and then released more slowly into the bulk. This suggests that the film could provide short-term protection from food oxidation. The films can be used for prolonging the shelf life of packed fat-rich foods.}, number={7}, journal={ACS SUSTAINABLE CHEMISTRY & ENGINEERING}, author={Ma, Qianyun and Cao, Lele and Liang, Tiegiang and Li, Jian and Lucia, Lucian A. and Wang, Lijuan}, year={2018}, month={Jul}, pages={8926–8934} }
 @article{li_wang_zeng_2006, title={Multiple-interval mapping for ordinal traits}, volume={173}, ISSN={["0016-6731"]}, DOI={10.1534/genetics.105.054619}, abstractNote={Abstract Many statistical methods have been developed to map multiple quantitative trait loci (QTL) in experimental cross populations. Among these methods, multiple-interval mapping (MIM) can map QTL with epistasis simultaneously. However, the previous implementation of MIM is for continuously distributed traits. In this study we extend MIM to ordinal traits on the basis of a threshold model. The method inherits the properties and advantages of MIM and can fit a model of multiple QTL effects and epistasis on the underlying liability score. We study a number of statistical issues associated with the method, such as the efficiency and stability of maximization and model selection. We also use computer simulation to study the performance of the method and compare it to other alternative approaches. The method has been implemented in QTL Cartographer to facilitate its general usage for QTL mapping data analysis on binary and ordinal traits.}, number={3}, journal={GENETICS}, author={Li, Jian and Wang, Shengchu and Zeng, Zhao-Bang}, year={2006}, month={Jul}, pages={1649–1663} }
 @article{li_deng_2005, title={Estimation of the rate and effects of deleterious genomic mutations in finite populations with linkage disequilibrium}, volume={95}, DOI={10.1038/sj.hdy.6800689}, abstractNote={Under several assumptions such as infinite population size with unlinked loci at linkage equilibrium (LD) under mutation-selection (M-S) balance, the rate (U), and the average effects (dominance and selection coefficients h and s) of deleterious genomic mutations (DGM) can be estimated by the Deng-Lynch method in some natural populations. However, all natural populations are finite in size and many of them are not large enough to be considered as approximately infinite. In the absence of an analytical estimation approach to characterize DGM in finite populations, we test the robustness and applicability of the Deng-Lynch method in finite populations with computer simulations. The results indicate that the estimation obtained by the Deng-Lynch method in finite populations with LD is generally robust when population size is greater than 400. With constant mutation effects, in outcrossing populations, the estimates U and ĥ are unbiased or only slightly upwardly biased, and ŝ is unbiased for most cases. In highly selfing populations, U and ĥ are upwardly biased, U is no more than 1.5U and ĥ is less than 1.1 h, and ŝ is either unbiased or slightly downwardly biased. With variable mutation effects, U ranges from 0.56 to 0.72U, and s ranges from 1.4 to 1.8s. Generally speaking, with the same finite population size, the estimation in outcrossing populations is better than in highly selfing populations. Given that even the order of the magnitude of the parameters of DMG (U in particular) is controversial, our investigation here may provide a basis for using the Deng-Lynch method to characterize DGM in finite populations of size greater than 400 in the presence of LD.}, number={1}, journal={Heredity}, author={Li, J. and Deng, H. W.}, year={2005}, pages={59–68} }
 @article{li_martin_jeffers_dean_camberato_2005, title={Genetic variation among Rhizoctonia solani isolates from warm-season turfgrasses}, volume={10}, journal={International Turfgrass Society Research Journal}, author={Li, J. F. and Martin, S. B. and Jeffers, S. N. and Dean, R. A. and Camberato, J. J.}, year={2005}, pages={230} }
 @article{moehring_li_schug_smith_deangelis_mackay_coyne_2004, title={Quantitative trait loci for sexual isolation between Drosophila simulans and D-mauritiana}, volume={167}, ISSN={["1943-2631"]}, DOI={10.1534/genetics.103.024364}, abstractNote={Sexual isolating mechanisms that act before fertilization are often considered the most important genetic barriers leading to speciation in animals. While recent progress has been made toward understanding the genetic basis of the postzygotic isolating mechanisms of hybrid sterility and inviability, little is known about the genetic basis of prezygotic sexual isolation. Here, we map quantitative trait loci (QTL) contributing to prezygotic reproductive isolation between the sibling species Drosophila simulans and D. mauritiana. We mapped at least seven QTL affecting discrimination of D. mauritiana females against D. simulans males, three QTL affecting D. simulans male traits against which D. mauritiana females discriminate, and six QTL affecting D. mauritiana male traits against which D. simulans females discriminate. QTL affecting sexual isolation act additively, are largely different in males and females, and are not disproportionately concentrated on the X chromosome: The QTL of greatest effect are located on chromosome 3. Unlike the genetic components of postzygotic isolation, the loci for prezygotic isolation do not interact epistatically. The observation of a few QTL with moderate to large effects will facilitate positional cloning of genes underlying sexual isolation.}, number={3}, journal={GENETICS}, author={Moehring, AJ and Li, JA and Schug, MD and Smith, SG and deAngelis, M and Mackay, TFC and Coyne, JA}, year={2004}, month={Jul}, pages={1265–1274} }