Works (69)

Updated: August 12th, 2023 21:14

2006 journal article

A population-based latent variable approach for association mapping of quantitative trait loci

ANNALS OF HUMAN GENETICS, 70, 506–523.

By: T. Wang*, B. Weir n & Z. Zeng n

author keywords: association mapping; maximum likelihood; haplotype; latent variable; EM algorithm
MeSH headings : Algorithms; Chromosome Mapping; Computer Simulation; Genetics, Population / methods; Humans; Likelihood Functions; Linkage Disequilibrium / genetics; Models, Genetic; Quantitative Trait Loci; Statistics as Topic
TL;DR: Under a general likelihood framework, an EM‐based algorithm is developed to estimate genetic effects of the QTL and haplotype frequencies of theQTL and markers jointly and provides a joint test for association between a quantitative trait and marker genotypes without requiring adjustment for the multiple testing. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2006 journal article

It was one of my brothers

INTERNATIONAL JOURNAL OF LEGAL MEDICINE, 120(2), 95–104.

By: A. Anderson n & B. Weir n

author keywords: forensic science; match probability; DNA profile; relatives
MeSH headings : DNA Fingerprinting / methods; Forensic Genetics; Gene Frequency; Genotype; Humans; Male; Models, Genetic; Monte Carlo Method; Pedigree; Siblings
TL;DR: This study discusses methods for evaluating the probability that at least one of a set of the suspect's full or half-siblings shares the suspects' DNA profile and presents three such methods: exact calculation, estimation via Monte Carlo simulations, and estimation by means of sandwiches the probability between an upper and a lower bound. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2005 journal article

Genotypic probabilities for pairs of inbred relatives

Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences, 360(1459), 1379–1385.

By: W. Liu & B. Weir

Source: NC State University Libraries
Added: August 6, 2018

2005 journal article

Measures of human population structure show heterogeneity among genomic regions

Genome Research, 15(11), 1468–1476.

By: B. Weir n, L. Cardon*, A. Anderson n, D. Nelson & W. Hill*

MeSH headings : Chromosomes, Human / genetics; Ethnicity / genetics; Genetic Heterogeneity; Genetics, Population; Genome, Human / genetics; Genomics / methods; Haplotypes / genetics; Humans; Linkage Disequilibrium / genetics; Polymorphism, Single Nucleotide / genetics; United States
TL;DR: Estimates of genetic population structure (F(ST) were constructed from all autosomes in two large SNP data sets, and it is shown that individual-marker estimates are too variable to be useful. (via Semantic Scholar)
Sources: Web Of Science, Crossref
Added: August 6, 2018

2005 review

The quantitative genetics of transcription

[Review of ]. TRENDS IN GENETICS, 21(11), 616–623.

By: G. Gibson n & B. Weir n

MeSH headings : Chi-Square Distribution; Chromosome Mapping; Evolution, Molecular; Genetic Variation; Humans; Quantitative Trait Loci; Transcription, Genetic
TL;DR: Several studies imply pervasive non-additivity of transcription, transgressive segregation and epistasis, and future studies will soon document the extent of genotype-environment interaction and population structure at the transcriptional level. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2004 journal article

Affected sib pair tests in inbred populations

Annals of Human Genetics, 68(Nov-04), 606–619.

By: W. Liu & B. Weir

Source: NC State University Libraries
Added: August 6, 2018

2004 journal article

Allele frequency data for profiler plus loci in Australia

Journal of Forensic Sciences, 49(5), 1121–1123.

By: B. Weir, A. Bagdonavicius, B. Blair, C. Eckhoff, C. Pearman, P. Stringer, J. Sutton, J. West, L. Wynen

Source: NC State University Libraries
Added: August 6, 2018

2004 journal article

Allelic association patterns for a dense SNP map

GENETIC EPIDEMIOLOGY, 27(4), 442–450.

By: B. Weir n, W. Hill* & L. Cardon*

author keywords: Hardy-Weinberg tests; composite linkage disequilibrium; inbreeding coefficient; case-control test
MeSH headings : Black or African American / genetics; Alleles; Asian People / genetics; Case-Control Studies; Chromosome Mapping / methods; Chromosomes, Human, Pair 20 / genetics; Genetic Predisposition to Disease / epidemiology; Genetics, Population; Genome, Human; Genotype; Haplotypes; Humans; Linkage Disequilibrium / genetics; Models, Genetic; Models, Statistical; Polymorphism, Single Nucleotide / genetics; White People / genetics
TL;DR: The observation that markers showing such departures are often close together on the chromosome confirms the result that Hardy‐Weinberg tests at two loci are correlated to an extent that depends on the linkage disequilibrium between those two markers. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2004 journal article

Comparison of Li-Wong and loglinear mixed models for the statistical analysis of oligonucleotide arrays

BIOINFORMATICS, 20(4), 500–506.

By: T. Chu n, B. Weir n & R. Wolfinger n

MeSH headings : Algorithms; Computer Simulation; DNA / chemistry; DNA / genetics; Gene Expression Profiling / methods; Linear Models; Models, Genetic; Models, Statistical; Oligonucleotide Array Sequence Analysis / methods; Reproducibility of Results; Sensitivity and Specificity
TL;DR: An empirical comparison of the two analysis-of-variance-style mixed models for probe-level, oligonucleotide array data based on a multiplicative parametrization is provided, and finds the models perform quite similarly across most genes, but with some interesting and important distinctions. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2004 journal article

Effect of Two- and Three-Locus Linkage Disequilibrium on the Power to Detect Marker/Phenotype Associations

Genetics, 168(2), 1029–1040.

By: D. Nielsen n, M. Ehm*, D. Zaykin* & B. Weir n

MeSH headings : Case-Control Studies; Computational Biology / methods; Computational Biology / statistics & numerical data; Genetic Markers / genetics; Genetic Variation / genetics; Genotype; Haplotypes; Humans; Linkage Disequilibrium / genetics; Phenotype; Polymorphism, Genetic / genetics; Quantitative Trait, Heritable
TL;DR: This work examines many different patterns of LD defined by both pairwise and joint multilocus LD terms, and examines how changes in these patterns affect the power to detect association when performing single-marker and haplotype-based case-control tests. (via Semantic Scholar)
Sources: Web Of Science, Crossref, NC State University Libraries
Added: August 6, 2018

2004 journal article

Matching and partial-matching DNA profiles

Journal of Forensic Sciences, 49(5), 1009–1014.

By: B. Weir

Source: NC State University Libraries
Added: August 6, 2018

2004 journal article

Moment estimation of population diversity and genetic distance from data on recessive markers

MOLECULAR ECOLOGY, 13(4), 895–908.

By: W. Hill* & B. Weir n

author keywords: amplified fragment length polymorphism; dominant markers; F-statistics; genetic diversity; population structure; sampling error
MeSH headings : Analysis of Variance; Animals; Evolution, Molecular; Genes, Recessive / genetics; Genetic Markers / genetics; Genetic Variation; Genetics, Population; Genotype; Models, Genetic; Polymorphism, Restriction Fragment Length; Species Specificity; Sus scrofa / genetics
TL;DR: A moment‐based method for estimating a measure of population diversity, θ or Wright's FST, is given for dominant markers such as amplified fragment length polymorphisms (AFLPs) or RAPDs in noninbred populations. (via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land (Web of Science)
Source: Web Of Science
Added: August 6, 2018

2004 journal article

Optimal testing strategies for large, sparse multinomial models

COMPUTATIONAL STATISTICS & DATA ANALYSIS, 46(3), 605–620.

By: P. Maiste* & B. Weir n

author keywords: conditional test; unconditional test; goodness-of-fit; Fisher's exact test; Hardy-Weinberg equilibrium
TL;DR: A comprehensive comparison of test statistics and testing strategies to test for independence at one locus with many alleles finds that Fisher's exact test is most appropriate for small samples, and the asymptotic chi-square goodness-of-fit statistic works well with large samples, relative to the number of multinomial categories. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2004 journal article

Properties of the multiallelic trend test

BIOMETRICS, 60(1), 69–74.

By: W. Czika* & B. Weir n

author keywords: case-control test; multiallelic markers; nongametic linkage disequilibrium
MeSH headings : Alleles; Biometry; Case-Control Studies; Chi-Square Distribution; Genetic Markers; Humans; Linkage Disequilibrium; Models, Genetic
TL;DR: It is shown here that the multiple‐allele version of Armitage's trend test has increased power over the two‐alleel version under the requirement of equifrequent alleles, but not in general. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2003 journal article

Dependency effects in multi-locus match probabilities

THEORETICAL POPULATION BIOLOGY, 63(3), 207–219.

By: C. Laurie* & B. Weir n

MeSH headings : Alleles; Chromosome Mapping / statistics & numerical data; Consanguinity; Gene Frequency; Genotype; Humans; Probability; United States
TL;DR: It is demonstrated that the product rule probability always underestimates the two-locus match probability, the probability that two individuals chosen at random will have the same genotype at both loci, with the probability computed as the product of the one- locus match probabilities. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2003 journal article

Effects of population structure and admixture on exact tests for association between loci

Genetics, 164(1), 381–387.

By: B. Law, J. Buckleton, C. Triggs & B. Weir

Source: NC State University Libraries
Added: August 6, 2018

2003 journal article

Issues and strategies in the DNA identification of World Trade Center victims

THEORETICAL POPULATION BIOLOGY, 63(3), 173–178.

By: C. Brenner & B. Weir n

MeSH headings : Aircraft; Crime Victims / classification; DNA Fingerprinting / statistics & numerical data; Forensic Anthropology / methods; Humans; Likelihood Functions; New York City; Terrorism
TL;DR: A simple and general formula for the likelihood ratio governing practically any potential relationship between two DNA profiles is presented, and a 3-stage paradigm is described to organize the work of sorting out the identities of the nearly 3000 victims of the World Trade Center attack. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2003 journal article

The International HapMap Project

NATURE, 426(6968), 789–796.

By: R. Gibbs, J. Belmont, P. Hardenbol, T. Willis, F. Yu, H. Yang, L. Ch'ang, W. Huang ...

MeSH headings : Base Sequence; DNA / genetics; Gene Frequency; Genetic Variation / genetics; Genome, Human; Genomics / methods; Haplotypes / genetics; Humans; International Cooperation; Polymorphism, Single Nucleotide / genetics; Public Sector; Racial Groups / genetics
TL;DR: The HapMap will allow the discovery of sequence variants that affect common disease, will facilitate development of diagnostic tools, and will enhance the ability to choose targets for therapeutic intervention. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2003 article

Uses of DNA and genetic markers for forensics and population studies

Weir, B. S. (2003, May). THEORETICAL POPULATION BIOLOGY, Vol. 63, pp. 171–172.

By: B. Weir*

UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2002 journal article

A systematic statistical linear modeling approach to oligonucleotide array experiments

MATHEMATICAL BIOSCIENCES, 176(1), 35–51.

By: T. Chu n, B. Weir n & R. Wolfinger n

author keywords: microarray; mixed model; split plot; probe
MeSH headings : Cells, Cultured; Humans; Models, Statistical; Oligonucleotide Array Sequence Analysis / methods; Radiation, Ionizing; Transcription, Genetic
TL;DR: The approach employs classical linear mixed models and operates on a gene-by-gene basis and simultaneously considers the data across all chips in an experiment, which can accommodate complex experiments involving many kinds of treatments and test for their effects at the probe level. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2002 journal article

Assessing sources of variability in microarray gene expression data

Biotechniques, 33(4), 916-.

By: S. Spruill, J. Lu, S. Hardy & B. Weir

Source: NC State University Libraries
Added: August 6, 2018

2002 review

Estimating F-statistics

[Review of ]. ANNUAL REVIEW OF GENETICS, 36, 721–750.

By: B. Weir n & W. Hill*

author keywords: population structure; forensic profiles; inbreeding; relatedness
MeSH headings : Genetics, Population; Models, Genetic
TL;DR: A moment estimator of, the coancestry coefficient for alleles within a population, was described by Weir & Cockerham in 1984 and is still widely cited, by relating functions of theta values to times of population divergence under a pure drift model. (via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land (Web of Science)
Source: Web Of Science
Added: August 6, 2018

2002 journal article

Sex-specific longevity associations defined by tyrosine hydroxylase-insulin-insulin growth factor 2 haplotypes on the 11p15.5 chromosomal region (vol 36, pg 1663, 2001)

Experimental Gerontology, 37(4), 607–608.

By: M. De Luca, G. Rose, M. Bonafe, S. Garasto, V. Greco, B. Weir, C. Franceschi, G. De Benedictis

Source: NC State University Libraries
Added: August 6, 2018

2002 journal article

Truncated product method for combining P-values

GENETIC EPIDEMIOLOGY, 22(2), 170–185.

By: D. Zaykin n, L. Zhivotovsky*, P. Westfall* & B. Weir n

author keywords: meta-analysis; multiple tests; genome-wide scans; microarrays; Bonferroni
MeSH headings : Genetic Linkage; Humans; Models, Genetic; Models, Statistical; Probability
TL;DR: A new procedure to take the product of only those P‐values less than some specified cut‐off value and to evaluate the probability of such a product, or a smaller value, under the overall hypothesis that all L hypotheses are true is presented. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2001 journal article

Affected sib pair tests in inbred populations.

American Journal of Human Genetics, 69(4), 2012.

By: W. Liu & B. Weir

Source: NC State University Libraries
Added: August 6, 2018

2001 article

Analysis of single nucleotide polymorphisms in candidate genes using the pedigree disequilibrium test

GENETIC EPIDEMIOLOGY, Vol. 21, pp. S441–S446.

By: S. Hardy n, B. Weir n, N. Kaplan* & E. Martin*

author keywords: association; linkage disequilibrium; pedigree disequilibrium test; SNPs
MeSH headings : Genetic Predisposition to Disease / genetics; Genetics, Population; Genotype; Humans; Linkage Disequilibrium; Models, Genetic; Polymorphism, Single Nucleotide; Quantitative Trait, Heritable
TL;DR: The results indicate that, using the pedigree disequilibrium test, functional disease‐associated SNPs can be successfully identified with a dense map of moderately polymorphic SNPs. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2001 journal article

Association Studies under General Disease Models

Theoretical Population Biology, 60(3), 253–263.

By: D. Nielsen n & B. Weir n

MeSH headings : Alleles; Apolipoproteins E / genetics; Chromosome Mapping / methods; Cytochrome P-450 CYP2D6 / genetics; Genetic Markers; Genetic Predisposition to Disease; Genotype; Haplotypes; Humans; Linkage Disequilibrium; Models, Genetic; Phenotype
TL;DR: A general framework to examine association mapping methods is adopted which helps to clarify the nature of case-control and transmission/disequilibrium-type tests and reveals the relationship between measures of association and coefficients of linkage disequilibrium. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, Crossref, NC State University Libraries
Added: August 6, 2018

2001 journal article

DNA typing results from two urban subpopulations of Pakistan

Journal of Forensic Sciences, 46(1), 111–115.

By: Z. Rahman, T. Afroze & B. Weir

Source: NC State University Libraries
Added: August 6, 2018

2001 journal article

Determining success of haplotyping algorithms using densely mapped genomic regions.

American Journal of Human Genetics, 69(4), 116.

By: D. Zaykin, M. Ehm & B. Weir

Source: NC State University Libraries
Added: August 6, 2018

2001 journal article

Estimating the total number of alleles using a sample coverage method

Genetics, 159(3), 1365–1373.

By: S. Huang & B. Weir

Source: NC State University Libraries
Added: August 6, 2018

2001 article

Introduction: Transmission/disequilibrium test/association group

GENETIC EPIDEMIOLOGY, Vol. 21, pp. S421–S422.

By: B. Weir n

TL;DR: There was much variation in the strength of association of SNPs with disease, up to 70% of which was explained by SNP allele frequency and distance from the functional polymorphism. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2001 journal article

Sex-specific longevity associations defined by Tyrosine Hydroxylase-Insulin-Insulin Growth Factor 2 haplotypes on the 11p15.5 chromosomal region

EXPERIMENTAL GERONTOLOGY, 36(10), 1663–1671.

By: M. De Luca*, G. Rose*, A. Bonafe*, S. Garasto*, V. Greco*, B. Weir n, C. Franceschi*, G. De Benedictis*

author keywords: centenarians; TH gene; INS gene; IGF2 gene; linkage disequilibrium
MeSH headings : Adult; Aged; Chromosome Mapping; Chromosomes, Human, Pair 11 / genetics; Female; Genetic Linkage; Genetic Markers; Haplotypes; Humans; Insulin / genetics; Insulin-Like Growth Factor II / genetics; Longevity / genetics; Male; Middle Aged; Polymorphism, Restriction Fragment Length; Sex Characteristics; Tyrosine 3-Monooxygenase / genetics
TL;DR: Analysis of two additional RFLP markers in the Insulin (INS) and Insulin Growth Factor 2 (IGF2) genes reinforced the involvement of the chromosomal region spanning from TH to IGF2 loci in controlling the longevity phenotype in humans. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2001 journal article

Testing the association of quantitative traits and haplotypes considering treatment effects.

American Journal of Human Genetics, 69(4), 1286.

By: Z. Meng, D. Zaykin, M. Ehm & B. Weir

Source: NC State University Libraries
Added: August 6, 2018

2000 journal article

Challenges facing statistical genetics

Journal of the American Statistical Association, 95(449), 319–322.

By: B. Weir

Source: NC State University Libraries
Added: August 6, 2018

2000 journal article

Conditional genotypic probabilities for microsatellite loci

Genetics, 155(4), 1973–1980.

By: J. Graham, J. Curran & B. Weir

Source: NC State University Libraries
Added: August 6, 2018

2000 personal communication

Letter to the editor of Biometrics

By: I. Evett, L. Foreman & B. Weir

Source: NC State University Libraries
Added: August 6, 2018

2000 review

What is the structure of human populations?

[Review of ]. Evolutionary Biology, 32(2000), 195–202.

By: B. Weir

Source: NC State University Libraries
Added: August 6, 2018

1999 journal article

A classical setting for associations between markers and loci affecting quantitative traits

Genetical Research, 74(3), 271–277.

By: D. Nielsen n & B. Weir n

MeSH headings : Animals; Genetic Markers; Humans; Mathematical Computing; Models, Genetic; Quantitative Trait, Heritable
TL;DR: It is considered that this greater-than-usual level of generality leads to additional insights, in a way reminiscent of Cockerham's decomposition of genetic variance into five terms: three terms in addition to the usual additive and dominance terms. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, Crossref, NC State University Libraries
Added: August 6, 2018

1999 review

Bayesian statistics in genetics - a guide for the uninitiated

[Review of ]. TRENDS IN GENETICS, 15(9), 354–358.

By: J. Shoemaker*, I. Painter* & B. Weir n

MeSH headings : Bayes Theorem; Biometry; Genetics / statistics & numerical data; Models, Genetic; Probability; Quantitative Trait, Heritable
TL;DR: The utility of a Bayesian perspective, especially for complex problems, is becoming increasingly clear to the statistics community; geneticists are also finding this framework useful and are increasingly utilizing the power of this approach. (via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land (Web of Science)
Source: Web Of Science
Added: August 6, 2018

1999 journal article

Interpreting DNA mixtures in structured populations

Journal of Forensic Sciences, 44(5), 987–995.

By: J. Curran, C. Triggs, J. Buckleton & B. Weir

Source: NC State University Libraries
Added: August 6, 2018

1998 journal article

A Bayesian characterization of Hardy-Weinberg disequilibrium

Genetics, 149(4), 2079–2088.

By: J. Shoemaker, I. Painter & B. Weir

Source: NC State University Libraries
Added: August 6, 2018

1998 journal article

A comparative study of sibship tests of linkage and/or association

AMERICAN JOURNAL OF HUMAN GENETICS, 63(5), 1507–1516.

By: S. Monks n, N. Kaplan* & B. Weir n

MeSH headings : Alleles; Case-Control Studies; False Positive Reactions; Genetic Diseases, Inborn / genetics; Genetic Linkage; Genetic Markers; Models, Genetic; Models, Statistical; Monte Carlo Method; Nuclear Family; Parents; Research Design
TL;DR: This paper proposes an extension of one of three recent family-based tests of association and linkage that utilize unaffected siblings as surrogates for untyped parents and describes and compares the four tests in the context of a complex disease for both biallelic and multialle Lic markers, as well as for sibships of different sizes. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

1998 book

Characterizing population structure for assigning weight to DNA matching profiles

Rockville, MD: National Institute of Justice.

By: B. Weir & J. Buckleton

Source: NC State University Libraries
Added: August 6, 2018

1998 journal article

Detecting Marker-Disease Association by Testing for Hardy-Weinberg Disequilibrium at a Marker Locus

The American Journal of Human Genetics, 63(5), 1531–1540.

By: D. Nielsen n, M. Ehm* & B. Weir n

MeSH headings : Alleles; Genes, Recessive; Genetic Diseases, Inborn / genetics; Genetic Markers; Genetic Predisposition to Disease; Heterozygote; Humans; Linkage Disequilibrium; Models, Genetic; Models, Statistical
TL;DR: It does not follow that the usual measures of linkage disequilibrium are zero, given disease heterogeneity, and care is needed in the drawing of inferences from marker Hardy-Weinberg disequilibria for disease-susceptibility loci with more than two alleles. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, Crossref, NC State University Libraries
Added: August 6, 2018

1998 book

Estimation of population structure parameters, final report

Rockville, MD: National Institute of Justice.

By: B. Weir

Source: NC State University Libraries
Added: August 6, 2018

1998 book

Interpreting DNA evidence: Statistical genetics for forensic scientists

Sunderland, MA: Sinauer Associates.

By: I. Evett & B. Weir

Source: NC State University Libraries
Added: August 6, 2018

1998 journal article

Marker selection for the transmission/disequilibrium test, in recently admixed populations

AMERICAN JOURNAL OF HUMAN GENETICS, 62(3), 703–712.

MeSH headings : Alleles; Gene Frequency; Genetics, Population; Humans; Linkage Disequilibrium; Models, Genetic
TL;DR: The consequences of collapsing a microsatellite into a two-allele marker are examined, and it is found that if there is random mating in the admixed population, then typically there is a collapsing for which the power of the TDT is greater than that for the original micros Satellite marker. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

1998 journal article

Setting bounds for the likelihood ratio when multiple hypotheses are postulated

Science and Justice, 38(1), 23–26.

By: J. Buckleton, I. Evett & B. Weir

Source: NC State University Libraries
Added: August 6, 2018

1998 chapter

Statistical methods employed in evaluation of single-locus probe results in criminal identity cases

In P. J. Lincoln & J. Thomson (Eds.), Forensic DNA profiling protocols (Methods in molecular biology (Clifton, N.J.) ; 98) (Vol. 98, pp. 83–96). Totowa, N.J.: Humana Press.

By: B. Weir

Ed(s): . P. J. Lincoln & J. Thomson

Source: NC State University Libraries
Added: August 6, 2018

1997 journal article

Bayesian analysis of DNA profiling data in forensic identification applications: discussion

Journal of the Royal Statistical Society. Series A, General, 160 (part3)(1997), 465–466.

By: B. Weir & I. Painter

Source: NC State University Libraries
Added: August 6, 2018

1997 journal article

Hardy-Weinberg testing for continuous data

Genetics, 147(4), 1965–1975.

By: L. McIntyre & B. Weir

Source: NC State University Libraries
Added: August 6, 2018

1997 journal article

Interpreting DNA mixtures

Journal of Forensic Sciences, 42(2), 213–222.

By: B. Weir, C. Triggs, L. Starling, L. Stowell, K. Walsh & J. Buckleton

Source: NC State University Libraries
Added: August 6, 2018

1997 journal article

Power studies for the transmission/disequilibrium tests with multiple alleles

American Journal of Human Genetics, 60(1997), 691–702.

By: N. Kaplan, E. Martin & B. Weir

Source: NC State University Libraries
Added: August 6, 2018

1997 journal article

Statistical issues in the search for genes?

Statistical Science, 12(1997), 195–219.

By: R. Doerge, Z. Zeng & B. Weir

Source: NC State University Libraries
Added: August 6, 2018

1997 journal article

Tests for linkage and association in nuclear families

AMERICAN JOURNAL OF HUMAN GENETICS, 61(2), 439–448.

By: E. Martin*, N. Kaplan* & B. Weir*

MeSH headings : Alleles; Chi-Square Distribution; Child; Genetic Diseases, Inborn / genetics; Genetic Linkage; Genetic Markers; Genetic Predisposition to Disease; Humans; Linkage Disequilibrium; Models, Genetic; Monte Carlo Method; Nuclear Family; Reproducibility of Results
TL;DR: Two statistics are proposed that give valid chi2 tests of the null hypothesis of no association or no linkage and generally are more powerful than the TDT with a single, randomly chosen, affected child from each family. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

1997 journal article

The occurrence and significance of epistatic variance for quantitative characters and its measurement in haploids

EVOLUTION, 51(2), 348–353.

By: A. Shaw*, B. Weir n & F. Shaw*

author keywords: epistasis; gene interactions; haploids; mosses; quantitative genetics; sib analysis; variance components
TL;DR: A model for detecting epistasis in organisms with a free‐living haploid stage in their life cycles is developed and it is shown that epistasis is indicated by greater variance among families of haploid progeny derived from individual diploids than among clonally replicated haploid sibs from the same sporophyte. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

1997 personal communication

Transmission/disequilibrium tests for multiallelic loci: reply

By: N. Kaplan, E. Martin & B. Weir

Source: NC State University Libraries
Added: August 6, 2018

1993 article

VARIANCES FOR DISTANCES BETWEEN PLANT SEQUENCES

NEW ZEALAND JOURNAL OF BOTANY, Vol. 31, pp. 317–322.

By: B. Weir n & B. Gaut n

author keywords: DNA SEQUENCE; EVOLUTIONARY DISTANCE; MUTATION; WITHIN-SPECIES VARIATION
TL;DR: Phylogenetic trees may be constructed from pairwise distances among the taxonomic units because of the growing amount of sequence data and the need to incorporate within-species sequence variation into measures of distance between sequences. (via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

1990 journal article

SAMPLING STRATEGIES FOR DISTANCES BETWEEN DNA-SEQUENCES

BIOMETRICS, 46(3), 551–572.

By: B. Weir n & C. Basten n

TL;DR: An aim of this paper is to show that there is also a role for readers of this journal in the design of surveys of DNA sequences, and to center on the use of sequence data in evolutionary studies, where some region of DNA is sequenced in several different species. (via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land (Web of Science)
Source: Web Of Science
Added: August 6, 2018

1990 journal article

THE VARIANCE OF SAMPLE HETEROZYGOSITY

THEORETICAL POPULATION BIOLOGY, 37(1), 235–253.

By: B. Weir n, J. Reynolds n & K. Dodds n

MeSH headings : Alleles; Chromosome Mapping; Gene Frequency / genetics; Gene Pool; Genetic Variation / genetics; Genetics, Population; Heterozygote; Humans; Models, Genetic; Selection, Genetic
TL;DR: The variance of sample heterozygosity, averaged over several loci, is studied in a variety of situations and methods for estimating the variance are discussed, with attention being paid to unbalanced data where not all loci are scored in all individuals. (via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land (Web of Science)
Source: Web Of Science
Added: August 6, 2018

1985 review

GENE CONVERSION MODELS

[Review of ]. JOURNAL OF THEORETICAL BIOLOGY, 116(1), 1–8.

By: B. Weir n, T. Ohta n & H. Tachida n

MeSH headings : Alleles; Chromosomes; Gene Conversion; Models, Genetic; Mutation; Probability; Selection, Genetic
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

1984 journal article

ESTIMATING F-STATISTICS FOR THE ANALYSIS OF POPULATION-STRUCTURE

EVOLUTION, 38(6), 1358–1370.

By: B. Weir* & C. Cockerham

UN Sustainable Development Goal Categories
15. Life on Land (Web of Science)
Source: Web Of Science
Added: August 6, 2018

1983 journal article

Estimation of the co-ancestry coefficient - basis for a short-term genetic-distance

Genetics, 105(3), 767–779.

By: J. Reynolds, B. Weir & C. Cockerham

Source: NC State University Libraries
Added: August 6, 2018

1980 journal article

EFFECT OF MATING STRUCTURE ON VARIATION IN INBREEDING

THEORETICAL POPULATION BIOLOGY, 18(3), 396–429.

By: B. Weir n, P. Avery n & W. Hill n

TL;DR: An analysis is made of the variation among individuals in finite populations of the proportion of their genes which are identical by descent, and the coefficient of variation in mean heterozygosity over the genome is related to that in nonidentity. (via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land (Web of Science)
Source: Web Of Science
Added: August 6, 2018

1980 journal article

Effect of mating structure on variation in linkage disequilibrium

Genetics, 95(2), 477.

By: B. Weir & W. Hill

Source: NC State University Libraries
Added: August 6, 2018

1979 journal article

INFERENCES ABOUT LINKAGE DISEQUILIBRIUM

BIOMETRICS, 35(1), 235–254.

By: B. Weir*

TL;DR: General use of Burrows' composite measure of linkage disequilibrium, whether or not random union of gametes is an appropriate assumption, is recommended and attention is given to small samples, where the non-normality of gene frequencies will have greatest effect on methods of inference based on normal theory. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

1978 journal article

Testing hypotheses about linkage disequilibrium with multiple alleles

Genetics, 88(3), 633.

By: B. Weir & C. Cockerham

Source: NC State University Libraries
Added: August 6, 2018

1976 journal article

Testing for selective neutrality of electrophoretically detectable protein polymorphisms

Genetics, 84(3), 639.

By: B. Weir, A. Brown & D. Marshall

Source: NC State University Libraries
Added: August 6, 2018

1974 journal article

BEHAVIOR OF PAIRS OF LOCI IN FINITE MONOECIOUS POPULATIONS

THEORETICAL POPULATION BIOLOGY, 6(3), 323–354.

By: B. Weir n & C. Cockerham n

MeSH headings : Genetics, Population; Mathematics; Models, Biological
TL;DR: Transition equations are established for descent measures for pairs of loci in finite randomly mating monoecious populations, and three quadrigenic moments are evaluated, including the variance of the linkage disequilibrium. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

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