Melissa M. Haskell

Works (1)

Updated: July 5th, 2023 15:58

2004 article

ClC-2 chloride secretion mediates prostaglandin-induced recovery of barrier function in ischemia-injured porcine ileum

Moeser, A. J., Haskell, M. M., Shifflett, D. E., Little, D., Schultz, B. D., & Blikslager, A. T. (2004, September 1). Gastroenterology, Vol. 127, pp. 802–815.

By: A. Moeser n, M. Haskell n, D. Shifflett n, D. Little n, B. Schultz* & A. Blikslager n 

Contributors: A. Moeser n, M. Haskell n, D. Shifflett n, D. Little n, B. Schultz* & A. Blikslager n 

MeSH headings : Animals; CLC-2 Chloride Channels; Chloride Channels / metabolism; Chlorides / metabolism; Dinoprostone / pharmacology; Electric Impedance; Female; Ileum / blood supply; Intestinal Mucosa / drug effects; Intestinal Mucosa / metabolism; Intestinal Mucosa / physiopathology; Ischemia / metabolism; Ischemia / physiopathology; Male; Models, Animal; Permeability / drug effects; Prostaglandins / pharmacology; Recovery of Function / drug effects; Recovery of Function / physiology; Swine
topics (OpenAlex): Barrier Structure and Function Studies; Neuroscience and Neuropharmacology Research; Ion Transport and Channel Regulation
TL;DR: ClC-2-mediated intestinal Cl - secretion restores TER in ischemia-injured intestine and may provide the basis for targeted pharmacologic therapy for diseases associated with impaired barrier function. (via Semantic Scholar)
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Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

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