Kennedy S. Wekesa

Works (2)

Updated: July 5th, 2023 16:02

2002 journal article

Impaired olfactory behavior in mice deficient in the a subunit of G(0)

BRAIN RESEARCH, 941(1-2), 62–71.

By: A. Luo n, E. Cannon n, K. Wekesa*, R. Lyman n, J. Vandenbergh n & R. Anholt  n

author keywords: G protein; knock-out mouse; olfaction; chemoreception; behavioral genetics; olfactory bulb
MeSH headings : Analysis of Variance; Animals; Behavior, Animal; Female; GTP-Binding Protein alpha Subunits; Heterotrimeric GTP-Binding Proteins / deficiency; Heterotrimeric GTP-Binding Proteins / genetics; Immunohistochemistry; Male; Mice; Mice, Knockout; Odorants; Olfactory Bulb / cytology; Olfactory Receptor Neurons; Phenotype; Smell / genetics
TL;DR: Gαo is necessary for the expression of olfactory behavior under normal conditions and dependent on genetic background, but is not essential for the formation and maintenance of glomeruli. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

1999 journal article

Differential expression of G proteins in the mouse olfactory system

BRAIN RESEARCH, 837(1-2), 117–126.

By: K. Wekesa n & R. Anholt  n

author keywords: G protein; olfaction; olfactory bulb; accessory olfactory bulb; olfactory neuron; chemotopic projection
MeSH headings : Animals; Antibody Specificity; Axons / metabolism; GTP-Binding Protein alpha Subunits; Heterotrimeric GTP-Binding Proteins / analysis; Heterotrimeric GTP-Binding Proteins / genetics; Immunohistochemistry; Mice; Olfactory Bulb / cytology; Olfactory Bulb / metabolism; Olfactory Pathways / cytology; Olfactory Pathways / metabolism; Olfactory Receptor Neurons / cytology; Olfactory Receptor Neurons / metabolism
TL;DR: Characterization of the expression patterns of G(i2) and G(o) in the olfactory projection is essential for future studies aimed at relating transmembrane signaling events to signal propagation, axon sorting and target innervation. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

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