Works (8)
Updated: July 5th, 2023 15:57
2019 journal article
Amplification-by-Polymerization in Biosensing for Human Genomic DNA Detection
ACS SENSORS, 4(4), 992–1000.
author keywords: amplification-by-polymerization; biosensors; genomic DNA detection; RAFT; ATRP
MeSH headings : Biosensing Techniques / methods; Chromosomes, Human, X / chemistry; Chromosomes, Human, Y / chemistry; DNA / blood; DNA / genetics; DNA Probes / chemistry; DNA Probes / genetics; Female; Genomics / methods; Genotype; Humans; Male; Nucleic Acid Hybridization; Photometry / methods; Polyethylene Glycols / chemical synthesis; Polyethylene Glycols / chemistry; Polymerization; Proof of Concept Study; Sex
TL;DR:
The potential of adopting the described sensing technique without PCR was demonstrated, which could further promote the development of a portable, PCR-free DNA sensing device for point-of-need applications.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: June 4, 2019
2007 journal article
Core-shell Au nanoparticle formation with DNA-polymer hybrid coatings using aqueous ATRP
BIOMACROMOLECULES, 8(5), 1385–1390.
MeSH headings : Coated Materials, Biocompatible / chemical synthesis; DNA / chemistry; Electrophoresis; Gold / chemistry; Microscopy, Electron, Transmission; Nanoparticles / chemistry; Polymers / chemistry; Water / chemistry
TL;DR:
A direct surface-grafting approach to forming DNA-containing polymer shells outside of Au nanoparticles using aqueous atom transfer radical polymerization (ATRP) was reported, providing the basis for DNA sensing in homogeneous solutions.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation
(OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2007 journal article
Surface passivation using oligo(ethylene glycol) in ATRP-assisted DNA detection
SENSORS AND ACTUATORS B-CHEMICAL, 129(1), 225–230.
author keywords: surface passivation; oligo(ethylene glycol); self-assembled monolayer; DNA sensing
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2006 journal article
DNA-accelerated atom transfer radical polymerization on a gold surface
LANGMUIR, 22(6), 2640–2646.
MeSH headings : Base Sequence; DNA, Single-Stranded / chemistry; Gold / chemistry; Nuclear Magnetic Resonance, Biomolecular
TL;DR:
The results show that the presence of DNA molecules, although at a less-than-1% surface coverage, significantly accelerated the growth rates of both poly(2-hydroxyethyl methacrylate) (PHEMA) and poly(oligoethylene glycol methacries) (POEGMA) at the beginning of the ATRP reactions.
(via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018
2006 journal article
Design, synthesis, and evaluation of efflux substrate-metal chelator conjugates as potential antimicrobial agents
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 17(3), 707–711.
author keywords: design; synthesis; efflux substrate-metal chelator conjugates; antimicrobial agents
MeSH headings : Anti-Bacterial Agents / chemical synthesis; Anti-Bacterial Agents / pharmacology; Bacillus subtilis / drug effects; Bacteria / drug effects; Bacteria / metabolism; Chelating Agents / chemical synthesis; Chelating Agents / pharmacology; Drug Design; Drug Resistance, Multiple, Bacterial; Escherichia coli / drug effects; Indicators and Reagents; Metals / metabolism; Microbial Sensitivity Tests; Structure-Activity Relationship
TL;DR:
A series of conjugates of metal chelators and efflux transporter substrates aimed at disrupting bacterial metal homeostasis to achieve bacterial killing were designed and synthesized.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2006 review
Radical polymerization in biosensing
[Review of ]. ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 386(3), 525–531.
author keywords: free radical polymerization; controlled; living radical polymerization; biosensors; biosensing
MeSH headings : Artifacts; Biosensing Techniques / methods; Free Radicals; Polymers; Surface Properties
TL;DR:
Advancements in surface modification aimed at improving sensor biocompatibility and reducing nonspecific background noises are discussed.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2005 journal article
Detection of DNA point mutation by atom transfer radical polymerization
ANALYTICAL CHEMISTRY, 77(15), 4698–4705.
MeSH headings : DNA / analysis; DNA / genetics; DNA / ultrastructure; Free Radicals / chemistry; Microscopy, Atomic Force; Molecular Structure; Point Mutation / genetics; Polyhydroxyethyl Methacrylate / chemistry; Spectrum Analysis
TL;DR:
A new DNA detection method in which polymer growth in atom transfer radical polymerization (ATRP) is used as a means to amplify detection signals and laid the groundwork for the future development of detector-free testing kits in single-nucleotide polymorphism screenings.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2004 journal article
Barcoding the microworld
Analytical Chemistry, 76(19), 353A–359.
Source: NC State University Libraries
Added: August 6, 2018
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