Nedal W. Safwat

Works (4)

Updated: July 5th, 2023 15:57

2012 article

Functional Recognition of the Modified Human tRNA (Lys3) (UUU) Anticodon Domain by HIV's Nucleocapsid Protein and a Peptide Mimic (vol 410, pg 698, year 2011)

Journal of Molecular Biology, Vol. 420, pp. 259–259.

By: W. Graham, L. Barley-Maloney, C. Stark, A. Kaur, C. Stolarchuk, B. Sproat, G. Leszczynska, A. Malkiewicz ...

Source: NC State University Libraries
Added: August 6, 2018

2011 journal article

Functional recognition of the modified human tRNA(UUU)(Lys3) anticodon domain by HIV's nucleocapsid protein and a peptide mimic

Journal of Molecular Biology, 410(4), 698–715.

By: W. Graham, L. Barley-Maloney, C. Stark, A. Kaur, K. Stolyarchuk, B. Sproat, G. Leszczynska, A. Malkiewicz ...

Source: NC State University Libraries
Added: August 6, 2018

2005 journal article

Transforming growth factor beta-activated kinase 1 is a key mediator of ovine follicle-stimulating hormone beta-subunit expression

ENDOCRINOLOGY, 146(11), 4814–4824.

By: N. Safwat n, J. Ninomiya-Tsuji n, A. Gore n & W. Miller n

MeSH headings : Activins / pharmacology; Animals; Cell Line; Enzyme Activation / physiology; Follicle Stimulating Hormone, beta Subunit / antagonists & inhibitors; Follicle Stimulating Hormone, beta Subunit / biosynthesis; Follicle Stimulating Hormone, beta Subunit / genetics; Follicle Stimulating Hormone, beta Subunit / metabolism; Humans; Inhibin-beta Subunits / pharmacology; Kinetics; Lactones / pharmacology; Luciferases / genetics; MAP Kinase Kinase Kinases / metabolism; Phosphorylation; Recombinant Fusion Proteins / biosynthesis; Recombinant Proteins / pharmacology; Resorcinols / pharmacology; Sheep; Transfection; p38 Mitogen-Activated Protein Kinases / metabolism
TL;DR: This study used 4.7 kb of the ovine FSHβ-promoter linked to luciferase (oFSHβLuc) plus a well-characterized activin-responsive construct, p3TPLuc, to investigate the hypothesis that Smad3, TGFβ-activated kinase 1 (TAK1), or both cause activationin-mediated induction of FSH. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2004 journal article

Rapid, efficient isolation of murine gonadotropes and their use in revealing control of follicle-stimulating hormone by paracrine pituitary factors

ENDOCRINOLOGY, 145(12), 5832–5839.

By: J. Wu*, P. Su*, N. Safwat*, J. Sebastian* & W. Miller*

MeSH headings : Activins / pharmacology; Animals; Cell Separation / methods; Follicle Stimulating Hormone / metabolism; Follistatin / pharmacology; Luteinizing Hormone / metabolism; Mice; Mice, Inbred Strains; Mice, Transgenic; Paracrine Communication / drug effects; Paracrine Communication / physiology; Pituitary Gland / cytology; Pituitary Gland / metabolism
TL;DR: Data show that paracrine factors from pituitary nongonadotropes can play a major role in controlling FSHbeta at the pituitaries level, including all cells that produce endocrine hormones. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

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