@article{elmore_basseches_anhalt_cullen_olivry_2005, title={Paraneoplastic pemphigus in a dog with splenic sarcoma}, volume={42}, ISSN={["1544-2217"]}, url={http://www.scopus.com/inward/record.url?eid=2-s2.0-13244258427&partnerID=MN8TOARS}, DOI={10.1354/vp.42-1-88}, abstractNote={ Paraneoplastic pemphigus (PNP) is an autoimmune blistering skin disease of humans that consists of characteristic skin lesions associated with concurrent neoplasia. in this study we provide histologic and serologic evidence to support a diagnosis of PNP in a dog with splenic sarcoma. Skin lesions consisted of widespread erosions involving haired skin, mucocutaneous junctions, and oral mucosa. Microscopic examination of skin and mucosae revealed lesions consistent with both pemphigus vulgaris and erythema multiforme. Immunoprecipitation confirmed that circulating IgG autoantibodies from this patient recognized five distinct antigens, presumed to represent epidermal plakins. Clinical, histopathologic, and immunologic findings in this patient were similar to those observed in human patients with PNP. The splenic neoplasia in this dog was diagnosed as a phenotypically variable spindle cell sarcoma. To date, only one other dog has been reported with PNP. This is the second reported case of canine PNP and the first patient in whom skin lesions were identified in association with splenic neoplasia. }, number={1}, journal={VETERINARY PATHOLOGY}, author={Elmore, SA and Basseches, J and Anhalt, GJ and Cullen, JM and Olivry, T}, year={2005}, month={Jan}, pages={88–91} } @article{de voe_geissler_elmore_rotstein_lewbart_guy_2004, title={Ranavirus-associated morbidity and mortality in a group of captive eastern box turtles (Terrapene carolina carolina)}, volume={35}, ISSN={["1042-7260"]}, DOI={10.1638/03-037}, abstractNote={Abstract Seven captive eastern box turtles (Terrapene carolina carolina) from a large collection of North American chelonians in North Carolina became acutely ill in the fall of 2002. Five of the turtles died. Clinical signs included cutaneous abscessation, oral ulceration or abscessation (or both), respiratory distress, anorexia, and lethargy. The predominant postmortem lesion was fibrinoid vasculitis of various organs, including skin, mucous membranes, lungs, and liver. No inclusion bodies were detected by histopathology or electron microscopy of formalin-fixed tissue. An iridovirus was isolated from tissues obtained postmortem from two of the box turtles that died. The virus was characterized by electron microscopy, polymerase chain reaction, and sequence analysis of a portion of the major capsid protein as a member of the genus Ranavirus.}, number={4}, journal={JOURNAL OF ZOO AND WILDLIFE MEDICINE}, author={De Voe, R and Geissler, K and Elmore, S and Rotstein, D and Lewbart, G and Guy, J}, year={2004}, month={Dec}, pages={534–543} }