2006 journal article

Analysis of biomechanical factors affecting stent-graft migration in an abdominal aortic aneurysm model

JOURNAL OF BIOMECHANICS, 39(12), 2264–2273.

By: Z. Li n & C. Kleinstreuer n

author keywords: stented abdominal aortic aneurysm; stent-graft migration; blood flow; stent-graft and aneurysm-wall interactions; computational parametric sensitivity analyses
TL;DR: Simulation results indicate that implanting a SG can significantly reduce sac pressure, mechanical stress, pulsatile wall motion, and maximum diameter change in AAAs; hence, it may restore normal blood flow and prevent AAA rupture effectively. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2006 journal article

Computational analysis of type II endoleaks in a stented abdominal aortic aneurysm model

JOURNAL OF BIOMECHANICS, 39(14), 2573–2582.

By: Z. Li n & C. Kleinstreuer n

author keywords: abdominal aortic aneurysm; stent-graft; type II endoleaks; computational fluid-structure interaction analysis; sac pressure; wall stress; estimation of aneurysm-rupture risk; theoretical stent-graft migration
MeSH headings : Algorithms; Aorta, Abdominal / physiopathology; Aorta, Abdominal / surgery; Aortic Aneurysm, Abdominal / physiopathology; Aortic Aneurysm, Abdominal / surgery; Biomechanical Phenomena; Blood Flow Velocity / physiology; Blood Pressure / physiology; Blood Viscosity; Computer Simulation; Hematocrit; Humans; Models, Cardiovascular; Postoperative Complications / etiology; Postoperative Complications / physiopathology; Pressure; Stents / adverse effects; Stress, Mechanical; Vascular Surgical Procedures / adverse effects
TL;DR: Simulation results indicate that the sac pressure caused by types IIa and IIb endoleaks depends largely on the inlet branch pressure, where the branch inlet pressure increases, the sacpressure may reach the systemic level and AAA-rupture is possible. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2006 journal article

Effects of major endoleaks on a stented abdominal aortic aneurysm

JOURNAL OF BIOMECHANICAL ENGINEERING-TRANSACTIONS OF THE ASME, 128(1), 59–68.

By: Z. Li n & C. Kleinstreuer n

author keywords: abdominal aortic aneurysm; stent-graft; type I endoleaks; computational analysis; sac pressure; hypertension; aneurysm rupture risk; stent-graft migration; wall stress
MeSH headings : Aorta, Abdominal / physiopathology; Aorta, Abdominal / surgery; Aortic Aneurysm, Abdominal / complications; Aortic Aneurysm, Abdominal / physiopathology; Aortic Aneurysm, Abdominal / surgery; Blood Flow Velocity; Blood Loss, Surgical / prevention & control; Blood Pressure; Blood Vessel Prosthesis / adverse effects; Computer Simulation; Humans; Models, Cardiovascular; Postoperative Hemorrhage / etiology; Postoperative Hemorrhage / physiopathology; Shear Strength; Stents / adverse effects; Stress, Mechanical; Treatment Outcome
TL;DR: Interestingly enough, the net downward force acting on the implant is significantly reduced; thus, in the presence of endoleaks, the risk of stent-graft migration may be mitigated, and both proximaltype I-a and distal type I-b endoleak may cause cavity pressures close to a patient's systemic pressure; however, with reduced pulsatility. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2005 journal article

A new wall stress equation for aneurysm-rupture prediction

ANNALS OF BIOMEDICAL ENGINEERING, 33(2), 209–213.

By: Z. Li n & C. Kleinstreuer n

author keywords: Laplace structure equation; abdominal aortic aneurysm; semi-empirical wall stress equation; AAA-rupture prediction
MeSH headings : Animals; Aortic Aneurysm, Abdominal / pathology; Aortic Aneurysm, Abdominal / physiopathology; Aortic Rupture / pathology; Aortic Rupture / physiopathology; Blood Flow Velocity; Blood Pressure; Computer Simulation; Diagnosis, Computer-Assisted / methods; Elasticity; Humans; Models, Cardiovascular; Prognosis; Risk Assessment / methods; Risk Factors; Severity of Illness Index; Shear Strength; Stress, Mechanical
TL;DR: A semi-empirical equation for the peak AAA-wall stress has been developed and can be readily used for AAA-rupture predictions or can be integrated into more elaborate AAA-assessment models. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2005 journal article

Blood flow and structure interactions in a stented abdominal aortic aneurysm model

MEDICAL ENGINEERING & PHYSICS, 27(5), 369–382.

By: Z. Li n & C. Kleinstreuer n

author keywords: fluid-structure interaction; stented abdominal aortic aneurysm; endovascular graft; sac pressure; wall stress; drag force; EVG migration
MeSH headings : Algorithms; Aorta, Abdominal; Aortic Aneurysm, Abdominal / diagnosis; Aortic Aneurysm, Abdominal / pathology; Aortic Rupture; Biophysical Phenomena; Biophysics; Blood Vessel Prosthesis; Blood Vessel Prosthesis Implantation; Hemodynamics; Humans; Hypertension; Models, Anatomic; Models, Cardiovascular; Models, Statistical; Models, Theoretical; Pressure; Time Factors
TL;DR: The validated numerical results show that a securely placed EVG shields the diseased AAA wall from the pulsatile blood pressure and hence keeps the maximum wall stress 20 times below the wall stress value in the non-stented AAA. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2005 journal article

Fluid-structure interaction effects on sac-blood pressure and wall stress in a stented aneurysm

JOURNAL OF BIOMECHANICAL ENGINEERING-TRANSACTIONS OF THE ASME, 127(4), 662–671.

By: Z. Li n & C. Kleinstreuer n

author keywords: stented aneurysm; computational fluid-structure interaction simulations; abdominal aortic aneurysm; sac pressure; wall stress
MeSH headings : Animals; Aorta, Abdominal / physiopathology; Aorta, Abdominal / surgery; Aortic Aneurysm, Abdominal / complications; Aortic Aneurysm, Abdominal / physiopathology; Aortic Aneurysm, Abdominal / surgery; Aortic Rupture / etiology; Aortic Rupture / physiopathology; Blood Flow Velocity; Blood Pressure; Blood Vessel Prosthesis; Computer Simulation; Humans; Models, Cardiovascular; Stents; Stress, Mechanical
TL;DR: Simulation results indicate that, even without the presence of endoleaks (blood flowing into the cavity), elevated sac pressure can occur due to complex fluid-structure interactions between the luminal blood flow, EVG wall, intra-sac stagnant blood, including an intra-luminal thrombus, and the aneurysm wall. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

journal article

Analysis and computer program for rupture-risk prediction of abdominal aortic aneurysms

Kleinstreuer, C., & Li, Z. H. Biomedical Engineering Online, 5.

By: C. Kleinstreuer & Z. Li

Source: NC State University Libraries
Added: August 6, 2018

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