Amber K. Goetz
Works (6)
Updated: July 5th, 2023 15:50
2009 journal article
Inhibition of Rat and Human Steroidogenesis by Triazole Antifungals
SYSTEMS BIOLOGY IN REPRODUCTIVE MEDICINE, 55(5-6), 214–226.
co-author countries:
United States of America 🇺🇸
author keywords: CYP17; myclobutanil; propiconazole; testosterone; triadimefon
MeSH headings : Animals; Antifungal Agents / pharmacology; Cell Line, Tumor; Humans; Male; Nitriles / pharmacology; Organ Culture Techniques; Rats; Rats, Wistar; Steroid 17-alpha-Hydroxylase / metabolism; Steroids / biosynthesis; Testosterone / biosynthesis; Triazoles / pharmacology
www.tandfonline.com (publisher PDF)
Source: Web Of Science
Added: August 6, 2018
2009 journal article
Mode of Action for Reproductive and Hepatic Toxicity Inferred from a Genomic Study of Triazole Antifungals
TOXICOLOGICAL SCIENCES, 110(2), 449–462.
co-author countries:
United States of America 🇺🇸
author keywords: myclobutanil; propiconazole; triadimefon; toxicogenomics; steroid metabolism
MeSH headings : Aging; Animals; Antifungal Agents / toxicity; Chemical and Drug Induced Liver Injury; Gene Expression Profiling / methods; Gene Expression Regulation / drug effects; Gene Regulatory Networks; Gestational Age; Infertility, Male / chemically induced; Infertility, Male / genetics; Infertility, Male / metabolism; Liver / drug effects; Liver / metabolism; Liver Diseases / genetics; Liver Diseases / metabolism; Male; Nitriles / toxicity; Oligonucleotide Array Sequence Analysis; Rats; Rats, Wistar; Reproduction / drug effects; Reproduction / genetics; Testis / drug effects; Testis / metabolism; Testosterone / genetics; Testosterone / metabolism; Triazoles / toxicity
Source: Web Of Science
Added: August 6, 2018
2009 journal article
Toxicogenomic effects common to triazole antifungals and conserved between rats and humans
TOXICOLOGY AND APPLIED PHARMACOLOGY, 238(1), 80–89.
co-author countries:
United States of America 🇺🇸
author keywords: Myclobutanil; Propiconazole; Triadimefon; Toxicogenomics; CAR; PXR
MeSH headings : Animals; Antifungal Agents / administration & dosage; Antifungal Agents / toxicity; Dose-Response Relationship, Drug; Gene Expression Profiling; Gene Expression Regulation / drug effects; Hepatocytes / drug effects; Hepatocytes / metabolism; Humans; Liver / drug effects; Liver / metabolism; Male; Nitriles / administration & dosage; Nitriles / toxicity; Rats; Rats, Sprague-Dawley; Rats, Wistar; Species Specificity; Time Factors; Toxicogenetics; Triazoles / administration & dosage; Triazoles / toxicity
Source: Web Of Science
Added: August 6, 2018
2007 journal article
Disruption of testosterone homeostasis as a mode of action for the reproductive toxicity of triazole fungicides in the male rat
Toxicological Sciences, 95(1), 227–239.
MeSH headings : Anal Canal / drug effects; Anal Canal / growth & development; Animals; Antifungal Agents / toxicity; Body Weight / drug effects; Cell Shape / drug effects; Dose-Response Relationship, Drug; Eating / drug effects; Female; Fertility / drug effects; Fungicides, Industrial / toxicity; Genitalia, Male / drug effects; Genitalia, Male / growth & development; Genitalia, Male / pathology; Homeostasis / drug effects; Liver / drug effects; Liver / pathology; Male; Nitriles / toxicity; Organ Size / drug effects; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Wistar; Reproduction / drug effects; Sexual Maturation / drug effects; Sperm Motility / drug effects; Spermatozoa / drug effects; Spermatozoa / pathology; Testosterone / blood; Time Factors; Triazoles / toxicity
Source: NC State University Libraries
Added: August 6, 2018
2006 journal article
Effect of conazole fungicides on reproductive development in the female rat
Reproductive Toxicology (Elmsford, N.Y.), 22(4), 647–658.
Source: NC State University Libraries
Added: August 6, 2018
2005 journal article
A database for tracking toxicogenomic samples and procedures
Reproductive Toxicology (Elmsford, N.Y.), 19(3), 411–419.
Source: NC State University Libraries
Added: August 6, 2018
