Pasha Peffer

Works (2)

Updated: July 5th, 2023 15:57

2007 journal article

Ontogeny of Carnitine Palmitoyltransferase I Activity, Carnitine-Km, and mRNA Abundance in Pigs throughout Growth and Development

The Journal of Nutrition, 137(4), 898–903.

By: P. Lyvers Peffer n, X. Lin n, S. Jacobi n, L. Gatlin n, J. Woodworth * & J. Odle n 

Contributors: P. Peffer n, X. Lin n, S. Jacobi n, L. Gatlin n, J. Woodworth * & J. Odle n 

MeSH headings : Aging / metabolism; Animal Feed; Animals; Animals, Newborn; Animals, Suckling / metabolism; Carnitine / metabolism; Carnitine O-Palmitoyltransferase / genetics; Carnitine O-Palmitoyltransferase / metabolism; Female; Gene Expression; Kinetics; Lipid Metabolism / physiology; Liver / metabolism; Male; Muscle, Skeletal / metabolism; Osmolar Concentration; RNA, Messenger / metabolism; Swine / growth & development; Swine / metabolism
TL;DR: It is suggested that postnatal increases in CPT I activity during the suckling period are accompanied by increased tissue carnitine, and the lack of hepatic C PT I mRNA induction and low activity reported in both tissues prior to 1 wk of age may limit postnatal lipid utilization during the piglet's transition to extra-uterine life. (via Semantic Scholar)
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Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018

2005 journal article

Hepatic β-oxidation and carnitine palmitoyltransferase I in neonatal pigs after dietary treatments of clofibric acid, isoproterenol, and medium-chain triglycerides

American Journal of Physiology-Regulatory, Integrative and Comparative Physiology, 288(6), R1518–R1524.

By: P. Peffer n, X. Lin n & J. Odle n 

Contributors: P. Peffer n, X. Lin n & J. Odle n 

author keywords: acyl-CoA oxidase; fatty acid oxidase; malonyl-CoA; peroxisome; peroxisome proliferator; activated receptor
MeSH headings : Adrenergic beta-Agonists / pharmacology; Animals; Animals, Newborn / metabolism; Carnitine O-Palmitoyltransferase / metabolism; Clofibric Acid / pharmacology; DNA Primers; DNA, Complementary / biosynthesis; DNA, Complementary / genetics; Diet; Glucose / metabolism; Hypolipidemic Agents / pharmacology; Indicators and Reagents; Isoproterenol / pharmacology; Liver / metabolism; Mitochondria, Liver / enzymology; Mitochondria, Liver / metabolism; Oxidation-Reduction; Palmitic Acids / metabolism; Peroxisomes / metabolism; RNA, Messenger / biosynthesis; RNA, Messenger / genetics; Reverse Transcriptase Polymerase Chain Reaction; Swine; Triglycerides / pharmacology
TL;DR: A suckling piglet model was used to study nutritional and pharmacologic means of stimulating hepatic fatty acid β-oxidation and its applications in nutrition and medicine. (via Semantic Scholar)
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Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018

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