Works (33)
Updated: July 5th, 2023 16:04
2005 article
A peptide directed against the N-terminus of MARCKS protein attenuates release of myeloperoxidase (MPO) from human and canine neutrophils in vitro.
404nOtfound, Vol. 2, p. A633.
Source: NC State University Libraries
Added: August 6, 2018
2005 patent
Culture system for mouse tracheal epithelial cells
Washington, DC: U.S. Patent and Trademark Office.
Source: NC State University Libraries
Added: August 6, 2018
2005 journal article
Modeling the airway epithelium in allergic asthma: Interleukin-13-induced effects in differentiated murine tracheal epithelial cells
In Vitro Cellular & Developmental Biology. Animal, 41(7), 217–224.
Source: NC State University Libraries
Added: August 6, 2018
2002 journal article
Secretion-competent mouse tracheal epithelial cell culture from the genetically altered mouse - Pathway analysis via gene array
Chest, 121(3), 79S.
TL;DR:
This work presents a new Epithelial Repair Model of In Vitro Gene Expression in an http://chestjournal.chestpubs.org/content/121/3_suppl/79S.xhtml ( distributed without the prior written permission of the copyright holder).
(via Semantic Scholar)
Source: NC State University Libraries
Added: August 6, 2018
2001 article
Differentiation of murine tracheal epithelial cells in vitro.
American Journal of Respiratory and Critical Care Medicine, Vol. 163, p. A225.
Source: NC State University Libraries
Added: August 6, 2018
2001 chapter
Interleukin-13 induced mucous cell hyperplasia in airway epithelium.
In Cilia and mucus: from development to respiratory disease. (pp. 253–263).
Source: NC State University Libraries
Added: August 6, 2018
2001 article
Interleukin-13, a mediator of subepithelial fibrosis, enhances growth factor production and proliferation in human airway epithelial cells
Booth, B., Bonner, J., Akley, N., Macchione, M., Adler, K., & Martin, L. D. (2001, July). CHEST, Vol. 120, pp. 15S–15S.
TL;DR:
Injured airways with regions of regenerating/differentiating cells and regions of normal fully differentiated cells have been mimicked by examining the effects of IL-13 on normal human bronchial epithelial cells during mucociliary differentiation in air/liquid interface culture.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2000 chapter
Air-liquid interface culture systems for exposure of differentiated cells to oxidant stress.
In Models and methods in cell signaling and gene expression applications to oxidative stress research. (pp. 15–30).
Source: NC State University Libraries
Added: August 6, 2018
2000 journal article
Effects of TNF-alpha on expression of ICAM-1 in human airway epithelial cells in vitro - Signaling pathways controlling surface and gene expression
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, 22(6), 685–692.
MeSH headings : Antibodies, Monoclonal; Bronchi / cytology; Cell Line; Epithelial Cells / enzymology; Epithelial Cells / immunology; Flow Cytometry; Gene Expression / immunology; Humans; In Vitro Techniques; Intercellular Adhesion Molecule-1 / genetics; Intercellular Adhesion Molecule-1 / immunology; L-Lactate Dehydrogenase / metabolism; NF-kappa B / genetics; NF-kappa B / metabolism; Promoter Regions, Genetic / physiology; RNA Processing, Post-Transcriptional / physiology; RNA, Messenger / genetics; RNA, Messenger / metabolism; Respiratory Mucosa / cytology; Signal Transduction / immunology; Tumor Necrosis Factor-alpha / pharmacology
TL;DR:
The intracellular signaling pathway leading to enhanced expression appeared to involve activation of a phospholipase C that hydrolyzes phosphatidylcholine (PC-PLC) becaus...
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2000 article
Interaction of TGF? and EGF receptor mediates IL-13 induced mucous cell hyperplasia in human airway epithelium in vitro.
American Journal of Respiratory and Critical Care Medicine, Vol. 161, p. A779.
Source: NC State University Libraries
Added: August 6, 2018
1999 article
Tumor necrosis factor-alpha stimulates mucin secretion and cyclic GMP production by guinea pig tracheal epithelial cells in vitro
Fischer, B. M., Rochelle, L. G., Voynow, J. A., Akley, N. J., & Adler, K. B. (1999, March). AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, Vol. 20, pp. 413–422.
MeSH headings : Animals; Cyclic GMP / biosynthesis; Cyclic GMP-Dependent Protein Kinases; Epithelial Cells / cytology; Epithelial Cells / drug effects; Epithelial Cells / immunology; Female; Guanylate Cyclase / metabolism; Guinea Pigs; Male; Models, Biological; Mucins / metabolism; Nitric Oxide / biosynthesis; Nitric Oxide Synthase / metabolism; Protein Kinase C / antagonists & inhibitors; Protein Kinases / metabolism; Signal Transduction; Trachea / cytology; Trachea / drug effects; Trachea / immunology; Tumor Necrosis Factor-alpha / pharmacology; Type C Phospholipases / antagonists & inhibitors
TL;DR:
The results suggest that TNF-alpha stimulates secretion of mucin by GPTE cells via a mechanism(s) dependent on PC-PLC and PKC, and involving activation of NOS, generation of NO, production of cGMP, and activation of PKG.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
1997 article
Inflammatory mediators increase intracellular reactive oxygen and nitrogen species (ROS/RNS) in airway epithelial cells.
American Journal of Respiratory and Critical Care Medicine, Vol. 155, p. A437.
Source: NC State University Libraries
Added: August 6, 2018
1997 article
Secretory inhibition by airway epithelium increases with age.
American Journal of Respiratory and Critical Care Medicine, Vol. 155, p. A427.
Source: NC State University Libraries
Added: August 6, 2018
1997 article
The role of reactive oxygen and nitrogen species in the response of airway epithelium to particulates
Martin, L. D., Krunkosky, T. M., Dye, J. A., Fischer, B. M., Jiang, N. F., Rochelle, L. G., … Adler, K. B. (1997, September). ENVIRONMENTAL HEALTH PERSPECTIVES, Vol. 105, pp. 1301–1307.
author keywords: reactive oxygen/nitrogen species; signal transduction; airway inflammation; mucin hypersecretion; ICAM-1; TNF-alpha
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
11. Sustainable Cities and Communities
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
1996 journal article
Oxidant stress stimulates mucin secretion and PLG in airway epithelium via a nitric oxide-dependent mechanism
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY, 271(5), L854–L861.
author keywords: airway epithelial cells; second messengers; nitric oxide; phospholipase C
MeSH headings : Animals; Cell Transformation, Viral; Cells, Cultured; Enzyme-Linked Immunosorbent Assay; Epithelium / drug effects; Epithelium / physiology; Guinea Pigs; Humans; Hydrogen Peroxide / pharmacology; Molsidomine / analogs & derivatives; Molsidomine / pharmacology; Mucins / biosynthesis; Mucins / metabolism; Nitric Oxide / pharmacology; Penicillamine / analogs & derivatives; Penicillamine / pharmacology; Peroxides / pharmacology; Reactive Oxygen Species; S-Nitroso-N-Acetylpenicillamine; Superoxides / pharmacology; Trachea / physiology; Type C Phospholipases / metabolism; Xanthine Oxidase; omega-N-Methylarginine / pharmacology; tert-Butylhydroperoxide
TL;DR:
The results suggest that intracellularly generated radical species of nitrogen and oxygen may be important modulators of the response of airway epithelial cells to external oxidant stress.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
1996 article
Tumor necrosis factor alpha (TNF alpha)-induced ICAM-1 surface expression in airway epithelial cells in vitro: Possible signal transduction mechanisms
CYTOKINES AND ADHESION MOLECULES IN LUNG INFLAMMATION, Vol. 796, pp. 30–37.
MeSH headings : Adult; Antigens, CD / metabolism; Antioxidants / pharmacology; Bronchi / cytology; Bronchi / metabolism; Cell Line; Epithelium / metabolism; Flow Cytometry; Humans; Intercellular Adhesion Molecule-1 / metabolism; Protein Kinase C / metabolism; Receptors, Tumor Necrosis Factor / metabolism; Receptors, Tumor Necrosis Factor, Type I; Signal Transduction; Tumor Necrosis Factor-alpha / pharmacology
TL;DR:
Results indicate that TNF alpha-induced ICAM-1 surface expression is a specific receptor-mediated response (TNF-R1), which is mediated by mechanisms dependent on PKC and intracellular reactive oxygen species.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
1996 article
Tumor necrosis factor-alpha (TNF?) induced mucin secretion: dependence on nitric oxide (NO) and cyclic GMP.
American Journal of Respiratory and Critical Care Medicine, Vol. 153, p. A538.
Source: NC State University Libraries
Added: August 6, 2018
1995 article
Effects of tumor necrosis factor alpha (TNF?) on expression of ICAM-1 and inflammation-associated genes in airway epithelial cells in vitro.
American Journal of Respiratory and Critical Care Medicine, Vol. 151, p. A366.
Source: NC State University Libraries
Added: August 6, 2018
1995 article
Endogenously-generated nitric oxide (NO) may be a key signaling molecule in hypersecretion of mucin by guinea pig tracheal epithelial (GPTE) cells in vitro.
American Journal of Respiratory and Critical Care Medicine, Vol. 151, p. A337.
Source: NC State University Libraries
Added: August 6, 2018
1995 article
Reactive nitrogen species (RNS) stimulate secretion of mucin by primary cultures of guinea pig tracheal epithelial (GPTE) cells.
American Journal of Respiratory and Critical Care Medicine, Vol. 151, p. A337.
Source: NC State University Libraries
Added: August 6, 2018
1994 article
Effects of oxidant stress on airway epithelial cells in vitro.
FASEB Journal, Vol. 8, p. A896.
Source: NC State University Libraries
Added: August 6, 2018
1994 article
Reactive oxygen species (ROS) activate phospholipase C in guinea pig and human airway epithelial cells in vitro.
American Journal of Respiratory and Critical Care Medicine, Vol. 149, p. A315.
Source: NC State University Libraries
Added: August 6, 2018
1994 article
Tumor necrosis factor alpha (TNF?) stimulates mucin secretion and gene expression in airway epithelium in vitro.
Proceedings of the 37th Aspen Lung Conference., Vol. 37, p. 17.
Source: NC State University Libraries
Added: August 6, 2018
1992 article
Ozone increases platelet activating factor and activates phospholipases (PLA2 and PLC) in primary guinea pig tracheal epithelial cells (GPTE).
American Review of Respiratory Disease, Vol. 145, p. A99.
Source: NC State University Libraries
Added: August 6, 2018
1991 article
Airway epithelium generates and releases reactive oxygen species in response to activation of protein kinase C.
Proceedings Fo the 4th International Conference on Environmental Lung Disease (Montreal, 1991), Vol. 4, p. 2.
Source: NC State University Libraries
Added: August 6, 2018
1991 article
Effects of inflammatory mediators on generation and release of reactive oxygen species by airway epithelium in vitro.
Proceedings of the 34th Aspen Lung Conference., Vol. 34, p. 33.
Source: NC State University Libraries
Added: August 6, 2018
1991 chapter
Methods to study interactions between inhaled substances and epithelium of the respiratory tract in vitro.
In Microbeam analysis- 1990. (pp. 457–458).
Source: NC State University Libraries
Added: August 6, 2018
1991 article
Platelet activating factor provokes release of mucin like glycoproteins from guinea pig tracheal epithelial cells via a lipoxygenase-dependent mechanism.
American Review of Respiratory Disease, Vol. 143, p. A147.
Source: NC State University Libraries
Added: August 6, 2018
1990 article
Oxygen metabolites stimulate inositol lipid turnover in guinea pig airway epithelial cells in organotypic culture.
American Review of Respiratory Disease, Vol. 141, p. A107.
Source: NC State University Libraries
Added: August 6, 2018
1989 chapter
A novel culture system for maintaining differentiated epithelial cells between air and liquid phases: A possible model for studying interactions between mineral fibers, gases and airway epithelium.
In Biological interaction of inhaled mineral fibers and cigarette smoke (pp. 381–390).
Source: NC State University Libraries
Added: August 6, 2018
1989 article
Oxidant injury to rodent airway epithelium in primary culture stimulates intracellular production of oxygen free radicals, arachidonic acid metabolism, and mucin secretion.
American Review of Respiratory Disease, Vol. 139, p. A403.
Source: NC State University Libraries
Added: August 6, 2018
1988 article
Oxidant injury to airway epithelium in vitro stimulates cyclooxygenase metabolism of arachidonic acid and secretion of mucin.
Journal of Cell Biology, Vol. 107, p. 350a.
Source: NC State University Libraries
Added: August 6, 2018
1988 chapter
Oxygen radicals stimulate secretion of mucin by rodent airway epithelial cells in organotypic culture.
In Oxy radicals in molecular biology and pathology (pp. 101–108).
Source: NC State University Libraries
Added: August 6, 2018
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