Hao Mei

Works (3)

Updated: July 5th, 2023 15:57

2007 journal article

Multifactor dimensionality reduction-phenomics: A novel method to capture genetic heterogeneity with use of phenotypic variables

AMERICAN JOURNAL OF HUMAN GENETICS, 81(6), 1251–1261.

By: H. Mei n, M. Cuccaro* & E. Martin *

MeSH headings : Chromosome Mapping; Genetic Diseases, Inborn / genetics; Genetic Variation; Genotype; Humans; Models, Genetic; Models, Theoretical; Phenotype; Regression Analysis
TL;DR: MDR-Phenomics, a novel approach based on the multifactor dimensionality reduction (MDR) method, to detect genetic effects in pedigree data by integration of phenotypic covariates (PCs) that may reflect genetic heterogeneity, is presented. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2005 journal article

Extension of multifactor dimensionality reduction for identifying multilocus effects in the GAW14 simulated data

BMC Genetics, 6.

By: H. Mei, D. Ma, A. Ashley-Koch & E. Martin

Source: NC State University Libraries
Added: August 6, 2018

2005 journal article

Identification of significant association and gene-gene interaction of GABA receptor subunit genes in autism

AMERICAN JOURNAL OF HUMAN GENETICS, 77(3), 377–388.

By: D. Ma*, P. Whitehead*, M. Menold, E. Martin *, A. Ashley-Koch *, H. Mei n, M. Ritchie *, G. DeLong* ...

MeSH headings : Autistic Disorder / genetics; Genetic Markers / genetics; Genetic Predisposition to Disease / genetics; Genetic Testing; Genotype; Haplotypes / genetics; Humans; Logistic Models; Models, Genetic; Multifactorial Inheritance / genetics; Pedigree; Polymorphism, Single Nucleotide; Receptors, GABA-A / genetics; United States; White People / genetics
TL;DR: GABRA4 is involved in the etiology of autism and potentially increases autism risk through interaction with GABRB1, and the hypothesis that GABA receptor subunit genes are involved in autism, most likely via complex gene-gene interactions is supported. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

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