Michael Monine

Works (3)

Updated: July 5th, 2023 15:57

2008 journal article

Signal transduction at point-blank range: Analysis of a spatial coupling mechanism for pathway crosstalk

BIOPHYSICAL JOURNAL, 95(5), 2172–2182.

By: M. Monine n & J. Haugh n 

MeSH headings : Algorithms; Cell Membrane / metabolism; Computer Simulation; Models, Biological; Phosphatidylinositol 3-Kinases / metabolism; Receptor Cross-Talk; Signal Transduction; ras Guanine Nucleotide Exchange Factors / metabolism; ras Proteins / metabolism
TL;DR: The concept of spatial coupling is introduced, wherein simultaneous recruitment of different enzymes to the same receptor scaffold facilitates crosstalk between different signaling pathways through the local release and capture of activated signaling molecules. (via Semantic Scholar)
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Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2006 journal article

Homogenization of boundary conditions for surfaces with regular arrays of traps

Journal of Chemical Physics, 124(3).

By: A. Berezhkovskii, M. Monine, C. Muratov & S. Shvartsman

Source: NC State University Libraries
Added: August 6, 2018

2005 journal article

Reactions on cell membranes: Comparison of continuum theory and Brownian dynamics simulations

JOURNAL OF CHEMICAL PHYSICS, 123(7).

By: M. Monine n & J. Haugh n 

MeSH headings : Algorithms; Biophysics / methods; Catalysis; Cell Membrane / metabolism; Chemistry, Physical / methods; Computer Simulation; Diffusion; Enzymes / chemistry; Models, Statistical; Models, Theoretical; Molecular Conformation; Signal Transduction; Static Electricity; Substrate Specificity
TL;DR: An efficient Brownian dynamics algorithm is developed that is especially suited for biochemical transduction of signals received by living cells and compared the simulation results with various continuum theories through prediction of effective enzymatic rate constant values. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

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