Works (3)
Updated: July 5th, 2023 15:57
2008 journal article
Signal transduction at point-blank range: Analysis of a spatial coupling mechanism for pathway crosstalk
BIOPHYSICAL JOURNAL, 95(5), 2172–2182.
MeSH headings : Algorithms; Cell Membrane / metabolism; Computer Simulation; Models, Biological; Phosphatidylinositol 3-Kinases / metabolism; Receptor Cross-Talk; Signal Transduction; ras Guanine Nucleotide Exchange Factors / metabolism; ras Proteins / metabolism
TL;DR:
The concept of spatial coupling is introduced, wherein simultaneous recruitment of different enzymes to the same receptor scaffold facilitates crosstalk between different signaling pathways through the local release and capture of activated signaling molecules.
(via Semantic Scholar)
open access via doi.org (publisher)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2006 journal article
Homogenization of boundary conditions for surfaces with regular arrays of traps
Journal of Chemical Physics, 124(3).
Source: NC State University Libraries
Added: August 6, 2018
2005 journal article
Reactions on cell membranes: Comparison of continuum theory and Brownian dynamics simulations
JOURNAL OF CHEMICAL PHYSICS, 123(7).
MeSH headings : Algorithms; Biophysics / methods; Catalysis; Cell Membrane / metabolism; Chemistry, Physical / methods; Computer Simulation; Diffusion; Enzymes / chemistry; Models, Statistical; Models, Theoretical; Molecular Conformation; Signal Transduction; Static Electricity; Substrate Specificity
TL;DR:
An efficient Brownian dynamics algorithm is developed that is especially suited for biochemical transduction of signals received by living cells and compared the simulation results with various continuum theories through prediction of effective enzymatic rate constant values.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
11. Sustainable Cities and Communities
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
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