Works (3)

Updated: July 5th, 2023 15:57

2009 journal article

Genomic Consequences of Background Effects on scalloped Mutant Expressivity in the Wing of Drosophila melanogaster

GENETICS, 181(3), 1065–1076.

MeSH headings : Animals; Drosophila Proteins / genetics; Drosophila melanogaster / anatomy & histology; Drosophila melanogaster / cytology; Drosophila melanogaster / genetics; Drosophila melanogaster / metabolism; Epistasis, Genetic; Gene Expression Regulation; Genetic Linkage; Genetic Variation; Genome, Insect / genetics; Genomics; Molecular Sequence Data; Mutation; Nuclear Proteins / genetics; Oligonucleotide Array Sequence Analysis; Transcription Factors / genetics; Transcription, Genetic; Wings, Animal / metabolism
TL;DR: This study demonstrates that phenotypic expressivity of the scallopedE3 (sdE3) mutation of Drosophila melanogaster is background dependent and is the result of at least one major modifier segregating between two standard lab wild-type strains and demonstrates that the epistatic interaction between sdE3 and an optomotor blind mutation is backgrounddependent. (via Semantic Scholar)
UN Sustainable Development Goal Categories
13. Climate Action (Web of Science)
15. Life on Land (Web of Science)
Source: Web Of Science
Added: August 6, 2018

2009 journal article

Pharmacogenetic association study of 30 genes with phenobarbital drug response in epileptic dogs

Pharmacogenetics and Genomics, 19(12), 911–922.

By: E. Kennerly*, Y. Idaghdour*, N. Olby n, K. Munana n & G. Gibson*

Contributors: E. Kennerly*, Y. Idaghdour*, N. Olby n, K. Munana n & G. Gibson*

author keywords: canine epilepsy; drug response; epoxide hydrolase; GABRA2; KCNQ3; pharmacogenetics; phenobarbital; SCN2A2
MeSH headings : Animals; Anticonvulsants / metabolism; Anticonvulsants / therapeutic use; Case-Control Studies; Dog Diseases / drug therapy; Dogs; Drug Resistance; Epilepsy / drug therapy; Epilepsy / veterinary; Pharmacogenetics; Phenobarbital / metabolism; Phenobarbital / therapeutic use; Polymorphism, Single Nucleotide
TL;DR: Further replication and assessment of breed specificity is required before these markers can be considered as predictive of responsiveness to phenobarbital in dogs, but on functional grounds may tag strong candidate genes. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018

2005 journal article

Microarray analysis of differentially expressed genes of primary tumors in the canine central nervous system


By: S. Thomson n, E. Kennerly n, N. Olby n, . Mickelson*, D. Hoffmann*, P. Dickinson*, G. Gibson n, M. Breen n

author keywords: cDNA microarray; canine choroid plexus tumor; ependymoma; glial tumor; meningioma
MeSH headings : Animals; Astrocytoma / genetics; Astrocytoma / veterinary; Brain Neoplasms / genetics; Brain Neoplasms / veterinary; Dog Diseases / genetics; Dogs; Ependymoma / genetics; Ependymoma / veterinary; Female; Gene Expression Regulation, Neoplastic / genetics; Glioblastoma / genetics; Glioblastoma / veterinary; Male; Meningeal Neoplasms / genetics; Meningeal Neoplasms / veterinary; Meningioma / genetics; Meningioma / veterinary; Oligodendroglioma / genetics; Oligodendroglioma / veterinary; Oligonucleotide Array Sequence Analysis / veterinary; Papilloma / genetics; Papilloma / veterinary
TL;DR: This report represents the first global gene expression analysis of different types of canine brain tumors by cDNA microarrays and might aid in the identification of potential candidate genes involved in tumor formation and progression. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

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