Works (4)
Updated: July 5th, 2023 15:56
2007 journal article
Expression and regulation of the beta-subunit of ovine follicle-stimulating hormone relies heavily on a promoter sequence likely to bind smad-associated proteins
ENDOCRINOLOGY, 148(9), 4500–4508.
MeSH headings : Animals; Follicle Stimulating Hormone / genetics; Follicle Stimulating Hormone, beta Subunit / genetics; Gene Expression Regulation; Promoter Regions, Genetic; Sheep; Smad Proteins / genetics
open access via academic.oup.com (publisher PDF)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2005 journal article
Conditional induction of ovulation in mice
BIOLOGY OF REPRODUCTION, 73(4), 681–687.
author keywords: assisted reproductive technology; anterior pituitary; follicle-stimulating hormone; gene regulation; ovulation
MeSH headings : Animals; Cells, Cultured; Doxycycline / pharmacology; Female; Follicle Stimulating Hormone / blood; Follicle Stimulating Hormone / genetics; Follicle Stimulating Hormone, beta Subunit / genetics; Follicle Stimulating Hormone, beta Subunit / metabolism; Genetic Engineering / methods; Male; Mice; Mice, Transgenic; Ovary / drug effects; Ovary / physiology; Ovulation / drug effects; Ovulation / genetics; Ovulation / physiology; Ovulation Induction / methods; Superovulation / genetics
TL;DR:
In summary, gene switch technology and normal FSH regulation were combined to effectively enhance ovulation in mice and the same strategy can be used with any genetic switch to increase ovulation (or any highly conserved physiology) in any mammal.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2005 journal article
Differential regulation of follicle stimulating hormone by activin A and TGFB1 in murine gonadotropes
Reproductive Biology and Endocrinology, 3.
Source: NC State University Libraries
Added: August 6, 2018
2005 journal article
Transforming growth factor beta-activated kinase 1 is a key mediator of ovine follicle-stimulating hormone beta-subunit expression
ENDOCRINOLOGY, 146(11), 4814–4824.
Contributors: N. Safwat n, J. Ninomiya-Tsuji n , n & W. Miller n
MeSH headings : Activins / pharmacology; Animals; Cell Line; Enzyme Activation / physiology; Follicle Stimulating Hormone, beta Subunit / antagonists & inhibitors; Follicle Stimulating Hormone, beta Subunit / biosynthesis; Follicle Stimulating Hormone, beta Subunit / genetics; Follicle Stimulating Hormone, beta Subunit / metabolism; Humans; Inhibin-beta Subunits / pharmacology; Kinetics; Lactones / pharmacology; Luciferases / genetics; MAP Kinase Kinase Kinases / metabolism; Phosphorylation; Recombinant Fusion Proteins / biosynthesis; Recombinant Proteins / pharmacology; Resorcinols / pharmacology; Sheep; Transfection; p38 Mitogen-Activated Protein Kinases / metabolism
TL;DR:
This study used 4.7 kb of the ovine FSHβ-promoter linked to luciferase (oFSHβLuc) plus a well-characterized activin-responsive construct, p3TPLuc, to investigate the hypothesis that Smad3, TGFβ-activated kinase 1 (TAK1), or both cause activationin-mediated induction of FSH.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: August 6, 2018
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