Dipak Barua

Works (4)

Updated: July 5th, 2023 15:56

2008 article

Computational Models of Tandem Src Homology 2 Domain Interactions and Application to Phosphoinositide 3-Kinase

Barua, D., Faeder, J. R., & Haugh, J. M. (2008, January 21). Journal of Biological Chemistry, Vol. 283, pp. 7338–7345.

By: D. Barua n, J. Faeder * & J. Haugh n 

MeSH headings : Animals; Humans; Kinetics; Models, Biological; Phosphatidylinositol 3-Kinases / chemistry; Phosphatidylinositol 3-Kinases / metabolism; Receptor, Platelet-Derived Growth Factor beta / chemistry; Receptor, Platelet-Derived Growth Factor beta / metabolism; Surface Plasmon Resonance / methods; src Homology Domains / physiology
topics (OpenAlex): Chronic Lymphocytic Leukemia Research; Protein Tyrosine Phosphatases; Glycosylation and Glycoproteins Research
TL;DR: To analyze the interactions between tandem SH2 domains and bisphosphorylated peptides, detailed kinetic models were formulated and applied to the phosphoinositide 3-kinase p85 regulatory subunit/platelet- derived growth factor β-receptor system and found homodimerization of full-length p85 was found to be an alternative mechanism for high avidity binding to phosphorylated platelet-derived growth factor receptors. (via Semantic Scholar)
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Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2007 article

Structure-Based Kinetic Models of Modular Signaling Protein Function: Focus on Shp2

Barua, D., Faeder, J. R., & Haugh, J. M. (2007, January 5). Biophysical Journal, Vol. 92, pp. 2290–2300.

By: D. Barua n, J. Faeder * & J. Haugh n 

MeSH headings : Computer Simulation; Enzyme Activation; Intracellular Signaling Peptides and Proteins / chemistry; Intracellular Signaling Peptides and Proteins / metabolism; Kinetics; Models, Biological; Models, Chemical; Models, Molecular; Phosphorylation; Protein Conformation; Protein Structure, Tertiary; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Protein Tyrosine Phosphatases / chemistry; Protein Tyrosine Phosphatases / metabolism; Protein Tyrosine Phosphatases / ultrastructure; SH2 Domain-Containing Protein Tyrosine Phosphatases; Structure-Activity Relationship
topics (OpenAlex): Protein Tyrosine Phosphatases; Galectins and Cancer Biology; Protein Kinase Regulation and GTPase Signaling
TL;DR: To the knowledge, this is the first kinetic model to fully consider the modular, multifunctional structure of a signaling protein, and the computational approach should be generally applicable to other complex intermolecular interactions. (via Semantic Scholar)
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Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2006 article

Supercritical-carbon dioxide-assisted cyclic deposition of metal oxide and metal thin films

Barua, D., Gougousi, T., Young, E. D., & Parsons, G. N. (2006, February 27). Applied Physics Letters, Vol. 88.

By: D. Barua n, T. Gougousi n, E. Young n & G. Parsons n 

Contributors: D. Barua n, T. Gougousi n, E. Young n & G. Parsons n 

topics (OpenAlex): Semiconductor materials and devices; Catalytic Processes in Materials Science; Mesoporous Materials and Catalysis
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2005 article

Metal Oxide Thin Films Deposited from Metal Organic Precursors in Supercritical CO2 Solutions

Gougousi, T., Barua, D., Young, E. D., & Parsons, G. N. (2005, September 2). Chemistry of Materials, Vol. 17, pp. 5093–5100.

By: T. Gougousi  n, D. Barua n, E. Young n & G. Parsons n 

Contributors: T. Gougousi  n, D. Barua n, E. Young n & G. Parsons n 

topics (OpenAlex): Semiconductor materials and devices; Catalytic Processes in Materials Science; Electronic and Structural Properties of Oxides
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6. Clean Water and Sanitation (OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

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