@article{merlo_sheats_elce_hunter_breuhaus_2009, title={Outbreak of Lawsonia intracellularis on a Standardbred breeding farm in North Carolina}, volume={21}, ISSN={["2042-3292"]}, DOI={10.2746/095777309X400333}, abstractNote={Lawsonia intracellularis is a cause of protein-losing enteropathy in weanling foals commonly causing signs including diarrhoea, oedema and unthrifty appearance. It has previously been reported as sporadic cases throughout the USA, Canada and Europe. Only recently have outbreaks on a single farm location been reported. The cases reported here are an example of multiple foals on a single farm testing serologically positive for L. intracellularis. These foals ranged in severity from asymptomatic to severely hypoproteinaemic and septic; however, none of the foals ever displayed diarrhoea, which is the most common presenting sign of this disease process.}, number={4}, journal={EQUINE VETERINARY EDUCATION}, author={Merlo, J. L. and Sheats, M. K. and Elce, Y. and Hunter, S. and Breuhaus, B. A.}, year={2009}, month={Apr}, pages={179–182} } @article{fogle_gerard_elce_little_morton_correa_blikslager_2008, title={Analysis of Sodium Carboxymethylcellulose Administration and Related Factors Associated with Postoperative Colic and Survival in Horses with Small Intestinal Disease}, volume={37}, ISSN={0161-3499 1532-950X}, url={http://dx.doi.org/10.1111/j.1532-950X.2008.00420.x}, DOI={10.1111/j.1532-950X.2008.00420.x}, abstractNote={Objective— To analyze the effect of the intraoperative use of sodium carboxymethylcellulose (CBMC) and related perioperative factors on postoperative colic and survival in horses that had abdominal surgery for colic. Study Design— Retrospective study. Animals— Horses (n=203) that had surgery for small intestinal disease; 33 horses had intraoperative administration of CBMC. Methods— Information was obtained from medical records for 170 horses that had surgery for colic before use of CBMC and 33 horses that had intraoperative CBMC. Kaplan–Meier survival curves were used to estimate median survival time and a Cox proportional hazards model was used to estimate the hazard ratio for the effect of CBMC and other perioperative variables on survival. Results— Seventy-five percent of horses administered CBMC survived to 180 days, whereas 75% of untreated horses survived 8 days (median survival time=18 days). Horses not administered CBMC were twice as likely to die compared with horses administered CBMC. Horses that had postoperative ileus (POI) were 1.4 times more likely to die than horses without ileus. Similarly, horses with signs of colic after surgery were 1.3 times more likely to die than horses without postoperative signs of colic. Conclusions— CBMC administration is seemingly protective against death and prolongs survival when used intraoperatively in horses with small intestine disease, particularly horses with postoperative colic or POI. Both POI and colic increased risk of death after surgery. Clinical Relevance— Intraoperative administration of CBMC in horses that have surgery for small intestinal disease may improve survival, possibly by reducing early adhesion formation.}, number={6}, journal={Veterinary Surgery}, publisher={Wiley}, author={Fogle, Callie A. and Gerard, Mathew P. and Elce, Yvonne A. and Little, Dianne and Morton, Alison J. and Correa, Maria T. and Blikslager, Anthony T.}, year={2008}, month={Aug}, pages={558–563} } @article{thamm_ehrhart_charles_elce_2008, title={Cyclooxygenase-2 Expression in Equine Tumors}, volume={45}, ISSN={["0300-9858"]}, DOI={10.1354/vp.45-6-825}, abstractNote={The enzyme cyclooxygenase-2 (COX-2) is expressed in some tumor and stromal tissues, and catalyzes production of prostaglandins with growth stimulatory, antiapoptotic, proangiogenic, and immunosuppressive properties. Pharmacologic inhibition of COX-2 is associated with antitumor activity in various human and canine malignancies. The purpose of this study was to assess COX-2 expression in a series of equine sarcoids, melanomas, and squamous-cell carcinomas (SCC). COX-2 expression was assessed in formalin-fixed paraffin-embedded tissues from 14 sarcoids, 11 melanomas, and 37 SCC that represent various anatomic sites by using standard immunohistochemical methods. COX-2 was expressed in 2 of 14 sarcoids, 7 of 11 melanomas, and 32 of 37 SCC, 56% of which demonstrated moderate-to-strong immunoreactivity. There were no differences in expression between anatomic sites. In conclusion, most equine SCC and many melanomas appear to express COX-2 and thus could respond to COX-2 inhibitor therapy.}, number={6}, journal={VETERINARY PATHOLOGY}, author={Thamm, D. H. and Ehrhart, E. J., III and Charles, J. B. and Elce, Y. A.}, year={2008}, month={Nov}, pages={825–828} } @article{elce_orsini_blikslager_2007, title={Expression of cyclooxygenase-1 and -2 in naturally occurring squamous cell carcinomas in horses}, volume={68}, ISSN={0002-9645}, url={http://dx.doi.org/10.2460/ajvr.68.1.76}, DOI={10.2460/ajvr.68.1.76}, abstractNote={Abstract Objective —To assess expression of cyclooxygenase (COX)-1 and -2 in naturally occurring squamous cell carcinomas (SCCs) and the analogous normal tissues in horses. Sample Population —Tissue samples collected from 3 conjunctival, 2 vulvar, 4 preputial, and 5 penile SCCs during surgical excision in 14 horses and from corresponding body regions (conjunctiva [n = 5 horses], vulva [2], prepuce [3], and penis [3]) in 5 horses euthanized for reasons unrelated to neoplasia. Procedures —Tissue samples were snap frozen in liquid nitrogen and stored at −80°C until analysis. Protein was extracted from the frozen tissues, and western blot analyses were performed. Nonneoplastic and abnormal tissues from each body region were run on the same blot, and blots were run in triplicate. Molecular-weight markers and COX-1 and 2 ovine standards (positive control samples) were run concurrently on the gels; negative control samples were not used. Results —All tissues, including the nonneoplastic and SCC tissues, expressed both COX-1 and -2 proteins. Conclusions and Clinical Relevance —Results indicated that the expression of COX proteins in both nonneoplastic and SCC-affected tissues in horses is markedly different from that in other species. The reason for the potential benefit of COX-2 inhibitors in horses and other species is unknown. Further research needs to be performed to evaluate the efficacy of COX-2 inhibitors as cancer treatments in horses. Investigation of the mechanisms of tumor development in horses should be performed to increase understanding of this disease and ascertain how the mechanisms differ from those in other animals.}, number={1}, journal={American Journal of Veterinary Research}, publisher={American Veterinary Medical Association (AVMA)}, author={Elce, Yvonne A. and Orsini, James A. and Blikslager, Anthony T.}, year={2007}, month={Jan}, pages={76–80} } @article{davis_posner_elce_2007, title={Gabapentin for the treatment of neuropathic pain in a pregnant horse}, volume={231}, ISSN={["1943-569X"]}, DOI={10.2460/javma.231.5.755}, abstractNote={Abstract Case Description —A 24-year-old 732-kg (1,610-lb) pregnant Belgian draft horse mare developed neuropathy and signs of intractable pain following colic surgery. Clinical Findings —Following recovery from colic surgery to treat compression of the small and large intestines because of a large fetus, the mare was noticed to have signs of femoral neuropathy involving the left hind limb. Within 36 hours after recovery, the mare developed signs of severe pain that were unresponsive to conventional treatment. No gastrointestinal tract or muscular abnormalities were found, and the discomfort was attributed to neuropathic pain. Treatment and Outcome —The mare was treated with gabapentin (2.5 mg/kg [1.1 mg/lb], PO, q 12 h). Shortly after this treatment was initiated, the mare appeared comfortable and no longer had signs of pain. Treatment was continued for 6 days, during which the dosage was progressively decreased, and the mare was discharged. The mare subsequently delivered a healthy foal. Clinical Relevance —Gabapentin appeared to be a safe, effective, and economical treatment for neuropathic pain in this horse.}, number={5}, journal={JAVMA-JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION}, author={Davis, Jennifer L. and Posner, Lysa P. and Elce, Yvonne}, year={2007}, month={Sep}, pages={755–758} } @article{garvican_elce_woolard_blikslager_2007, title={Preputial melanoma with systemic metastasis in a pony gelding and disseminated metastatic melanoma in a Thoroughbred gelding}, volume={19}, ISSN={["2042-3292"]}, url={http://www.scopus.com/inward/record.url?eid=2-s2.0-34447558345&partnerID=MN8TOARS}, DOI={10.2746/095777307x207646}, number={6}, journal={EQUINE VETERINARY EDUCATION}, author={Garvican, E. R. and Elce, Y. A. and Woolard, K. and Blikslager, A. T.}, year={2007}, month={Jul}, pages={312–315} } @article{poulsen_elce_frederico_remick_capucille_2006, title={Atresia coli in an alpaca cria}, volume={158}, ISSN={["0042-4900"]}, DOI={10.1136/vr.158.17.598}, abstractNote={Veterinary RecordVolume 158, Issue 17 p. 598-599 Short Communication Atresia coli in an alpaca cria K. P. Poulsen DVM, K. P. Poulsen DVM Department of Population Health and Pathobiology, North Carolina State University College of Veterinary Medicine, 4700 Hillsborough Street, Raleigh, NC, 27606 USA Dr Poulsen’s present address is Department of Medical Sciences, University of Wisconsin-Madison School of Veterinary Medicine, 2015 Linden Drive, Madison, WI 53706, USASearch for more papers by this authorY. A. Elce DVM, DipACVS, Y. A. Elce DVM, DipACVS Department of Population Health and Pathobiology, North Carolina State University College of Veterinary Medicine, 4700 Hillsborough Street, Raleigh, NC, 27606 USASearch for more papers by this authorL. M. Frederico DVM, L. M. Frederico DVM Department of Population Health and Pathobiology, North Carolina State University College of Veterinary Medicine, 4700 Hillsborough Street, Raleigh, NC, 27606 USASearch for more papers by this authorA. K. Remick DVM, A. K. Remick DVM Department of Clinical Sciences, North Carolina State University College of Veterinary Medicine, 4700 Hillsborough Street, Raleigh, NC, 27606 USASearch for more papers by this authorD. J. Capucille DVM, MS, DipAVBP, D. J. Capucille DVM, MS, DipAVBP Department of Clinical Sciences, North Carolina State University College of Veterinary Medicine, 4700 Hillsborough Street, Raleigh, NC, 27606 USASearch for more papers by this author K. P. Poulsen DVM, K. P. Poulsen DVM Department of Population Health and Pathobiology, North Carolina State University College of Veterinary Medicine, 4700 Hillsborough Street, Raleigh, NC, 27606 USA Dr Poulsen’s present address is Department of Medical Sciences, University of Wisconsin-Madison School of Veterinary Medicine, 2015 Linden Drive, Madison, WI 53706, USASearch for more papers by this authorY. A. Elce DVM, DipACVS, Y. A. Elce DVM, DipACVS Department of Population Health and Pathobiology, North Carolina State University College of Veterinary Medicine, 4700 Hillsborough Street, Raleigh, NC, 27606 USASearch for more papers by this authorL. M. Frederico DVM, L. M. Frederico DVM Department of Population Health and Pathobiology, North Carolina State University College of Veterinary Medicine, 4700 Hillsborough Street, Raleigh, NC, 27606 USASearch for more papers by this authorA. K. Remick DVM, A. K. Remick DVM Department of Clinical Sciences, North Carolina State University College of Veterinary Medicine, 4700 Hillsborough Street, Raleigh, NC, 27606 USASearch for more papers by this authorD. J. Capucille DVM, MS, DipAVBP, D. J. Capucille DVM, MS, DipAVBP Department of Clinical Sciences, North Carolina State University College of Veterinary Medicine, 4700 Hillsborough Street, Raleigh, NC, 27606 USASearch for more papers by this author First published: 29 April 2006 https://doi.org/10.1136/vr.158.17.598Citations: 6 AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookTwitterLinkedInRedditWechat No abstract is available for this article.Citing Literature Volume158, Issue17April 2006Pages 598-599 RelatedInformation}, number={17}, journal={VETERINARY RECORD}, author={Poulsen, KP and Elce, YA and Frederico, LM and Remick, AK and Capucille, DJ}, year={2006}, month={Apr}, pages={598–599} } @article{elce_southwood_nutt_nunamaker_2006, title={Ex vivo comparison of a novel tapered-sleeve and traditional full-limb transfixation pin cast for distal radial fracture stabilization in the horse}, volume={19}, number={2}, journal={Veterinary and Comparative Orthopaedics and Traumatology}, author={Elce, Y. A. and Southwood, L. L. and Nutt, J. N. and Nunamaker, D. M.}, year={2006}, pages={93–97} } @article{elce_2006, title={Infections in the equine abdomen and pelvis: Perirectal abscesses, umbilical infections, and peritonitis}, volume={22}, ISSN={["1558-4224"]}, DOI={10.1016/j.cveq.2006.04.002}, abstractNote={This article addresses the pathophysiology, diagnosis, management, and prognosis of several different infections within the equine abdomen and pelvic region. The latest advances in the diagnosis and treatment of perirectal abscesses, umbilical infections, and local and diffuse peritonitis are discussed. Emphasis is placed on recent advances in diagnostics and therapeutics with reference to human literature that may be useful in equine practice.}, number={2}, journal={VETERINARY CLINICS OF NORTH AMERICA-EQUINE PRACTICE}, author={Elce, Yvonne A.}, year={2006}, month={Aug}, pages={419-+} } @article{elce_kraus_orsini_2005, title={Mesh hernioplasty for repair of incisional hernias of the ventral body wall in large horses}, volume={17}, number={5}, journal={Equine Veterinary Education}, author={Elce, Y. A. and Kraus, B. M. and Orsini, J. A.}, year={2005}, pages={252–256} }